The invention discloses a gastrointestinal contrast agent which is prepared by uniformly mixing 60-80 weight parts of barium sulfate and 10-20 weight parts of traditional Chinese medicine extract, wherein the traditional Chinese medicine extract is prepared from the following raw material components: honeysuckle, astragalus, liquorice, bighead atractylodes rhizome, Poria cocos, Angelica sinensis, Chinese yam, medlar, plantain herb, hawthorn, Codonopsis pilosula, Chinese-date, Ligusticum wallichii, Rehmannia Glutinosa, dried tangerine or orange peel and glossy privet fruit. The contrast agent is clear in image, obvious in contrast and stable in physical and chemical properties, has the treatment effects of eliminating dampness and heat, regulating the flow of vital energy and soothing middle-Jiao and warming the middle-Jiao and invigorating the circulation of blood, can provide a protective effect for the gastrointestinal tract, relieves the symptoms such as stomachache, gastric acid, hematemesis and emesis of patients, is obvious in acid inhibition effect, does not have any adverse reaction, has high safety and comfort level and is suitable for clinical gastrointestinal conventional and special examination and ultrasound contrast.