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Preparation method and application of Chinese herbal immunostimulant for flatfish

An immune enhancer and Chinese herbal medicine technology, applied in the field of feed additives, can solve the problems of drug residues in aquatic products, affect the quality of aquatic products, and drug resistance of pathogenic bacteria, so as to improve digestion and absorption, efficiently regulate intestinal health, and maintain immune status. Effect

Inactive Publication Date: 2014-12-24
唐山联强畜牧药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Due to the limitation of the current disease control level, the prevention and control of flounder and flounder diseases is still dominated by chemical drugs. Frequent drug use causes pathogenic bacteria to develop drug resistance or mutation, making it difficult to control the disease, and then produces drug residues in aquatic products, which seriously affects the quality of aquatic products.

Method used

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  • Preparation method and application of Chinese herbal immunostimulant for flatfish

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] A Chinese herbal medicine immune enhancer for flounder and flounder, the specific preparation steps are as follows:

[0021] (1) Weighing: Accurately weigh Chinese herbal medicines according to the following formula: 12 parts of Hericium erinaceus, 12 parts of Artemisia annua, 8 parts of Codonopsis pilosula, 10 parts of honeysuckle, 3 parts of Poria cocos, 10 parts of Prunella vulgaris, 6 parts of licorice, and 5 parts of astragalus , 6 parts of Atractylodes macrocephala, 10 parts of forsythia, 6 parts of Fangfeng, 7 parts of hawthorn, 3 parts of Baibu;

[0022] (2) Preparation of compound Chinese herbal medicine: crush the weighed Chinese herbal medicine to 40-60 meshes, mix evenly, and prepare the compound Chinese herbal medicine;

[0023] (3) Ultrasonic-assisted extraction: add water with a mass ratio of 5 times to the compound Chinese herbal medicine powder, under the action of ultrasonic assist, reflux extraction at 100°C for 20-30min, ultrasonic power 400w, freque...

Embodiment 2

[0030] A Chinese herbal medicine immune enhancer for flounder and flounder, the specific preparation steps are as follows:

[0031] (1) Weighing: Accurately weigh Chinese herbal medicines according to the following formula: 18 parts of Hericium erinaceus, 8 parts of Artemisia annua, 12 parts of Codonopsis pilosula, 6 parts of honeysuckle, 5 parts of Poria cocos, 6 parts of Prunella vulgaris, 8 parts of licorice, and 3 parts of astragalus , 10 parts of Atractylodes macrocephala, 6 parts of forsythia, 10 parts of Fangfeng, 5 parts of hawthorn, 5 parts of Baibu;

[0032](2) Preparation of compound Chinese herbal medicine: crush the weighed Chinese herbal medicine to 40-60 meshes, mix evenly, and prepare the compound Chinese herbal medicine;

[0033] (3) Ultrasonic-assisted extraction: Add water with a mass ratio of 10 times to the compound Chinese herbal medicine powder, under the action of ultrasonic assist, reflux extraction at 100°C for 20-30min, ultrasonic power 400w, frequen...

Embodiment 3

[0040] A Chinese herbal medicine immune enhancer for flounder and flounder, the specific preparation steps are as follows:

[0041] (1) Weighing: Accurately weigh Chinese herbal medicines according to the following formula: 15 parts of Hericium erinaceus, 10 parts of Artemisia annua, 10 parts of Codonopsis pilosula, 8 parts of honeysuckle, 4 parts of Poria cocos, 8 parts of Prunella vulgaris, 7 parts of licorice, and 4 parts of astragalus , 8 parts of Atractylodes macrocephala, 8 parts of forsythia, 8 parts of Fangfeng, 6 parts of hawthorn, 4 parts of Baibu;

[0042] (2) Preparation of compound Chinese herbal medicine: crush the weighed Chinese herbal medicine to 40-60 meshes, mix evenly, and prepare the compound Chinese herbal medicine;

[0043] (3) Ultrasonic-assisted extraction: add water with a mass ratio of 7.5 times to the compound Chinese herbal medicine powder, under the action of ultrasonic assist, reflux extraction at 100°C for 20-30min, ultrasonic power 400w, freque...

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Abstract

The invention discloses a preparation method and application of a Chinese herbal immunostimulant for flatfish. The fermented Chinese herbal immunostimulant for the flatfish has multiple effects of prevention, health, treatment, immune regulation and the like, and is an ideal, green, environment-friendly, safe and novel feed additive for substituting antibiotics. The fermented Chinese herbal feed additive is prepared from hericium erinaceus, artemisia capillaris, codonopsis pilosula, honeysuckle, poria cocos, selfheal, liquorice, astragalus membranaceus, bighead atractylodes rhizome, fructus forsythiae, ledebouriella seseloides wolff., hawthorn, radix stemonae and other compound Chinese herbs by a process of ultrasound-assisted Chinese herb extraction and two-step fermentation of multi-strain aerobic fermentation and multi-strain anaerobic fermentation. The fermented Chinese herbal immunostimulant for the flatfish has dual advantages of Chinese herbs and probiotics, and can efficiently condition intestinal health of the flatfish, treat both symptoms and root causes, strength the foundation and invigorate Qi, maintain the intestinal microecological balance and an optimal immune state, improve digestion and absorption of nutrients, improve the body immunity of the flatfish, increase the farming income and reduce farming risks; as a substituent for the antibiotics, the fermented Chinese herbal immunostimulant has no adverse effect on the flatfish and is safe to use and free of drug residue, drug resistance and other problems; therefore, the fermented Chinese herbal immunostimulant has a broad market prospect.

Description

technical field [0001] The invention relates to a preparation method of a Chinese herbal medicine immune enhancer for flounder and flounder, belonging to the field of feed additives. Background technique [0002] Aquatic products are increasingly occupying an important share in people's daily diet. In order to meet the growing demand for aquatic products, it has become the focus of aquaculture to solve the physiological dysfunction and frequent diseases caused by the continuous expansion of aquaculture scale and the shortening of growth cycle. It is also the key to the development of the aquatic feed industry. In this context, antibiotic feed additives are popular and widely used in the feed industry, which has promoted the development of aquaculture industry to a certain extent, but the problems of high residue, high pollution and drug resistance caused by antibiotics are becoming more and more serious. serious. In the current society, food safety accidents occur frequent...

Claims

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Application Information

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IPC IPC(8): A23K1/18A23K1/14A23K1/16A61K36/904A61P37/04
CPCY02A40/818Y02P60/87
Inventor 董书阁侯文燕董静静段智岗侯文杰代书强
Owner 唐山联强畜牧药业有限公司
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