Applications of Xinnaoxin capsule in preparation of medicines treating Parkinson's disease
A technology of capsules and drugs, applied in the field of medicine, to achieve the effect of increasing positive expression, improving motor symptoms, and increasing content
Inactive Publication Date: 2015-01-07
三普药业有限公司
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- Abstract
- Description
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- Application Information
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Problems solved by technology
At present, the commonly used drugs in clinical treatment are levodopa and Madopa, etc., but their applications are limited due to their adverse reactions such as "switch effect".
[0003]Xinnaoxin Capsule is a product of Sanpu Pharmaceutical Co., Ltd., approved by Z20025866. No report
Method used
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Embodiment 1
[0013] The Xinnaoxin capsule is prepared by mixing 3 parts by weight of rhodiola rosea, 5 parts of wolfberry and 3 parts of seabuckthorn.
Embodiment 2
[0015] The Xinnaoxin capsule is prepared by mixing 4 parts by weight of rhodiola rosea, 10 parts of wolfberry and 6 parts of seabuckthorn.
Embodiment 3
[0017] The Xinnaoxin capsule is prepared by mixing 5 parts by weight of rhodiola rosea, 12 parts of wolfberry and 8 parts of seabuckthorn.
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Applications of a Xinnaoxin capsule in preparation of medicines treating Parkinson's disease are disclosed. The applications prove that: the Xinnaoxin capsule obviously improves behaviors of mouse with the Parkinson's disease, obviously increases the contents of DA and HVA in model mice corpus striatum and obviously enhances TH positive expression in the substantia nigra. Each dosage group of the Xinnaoxin capsule obviously improves movement symptoms of the mouse with the Parkinson's disease and effectively increases the contents of dopamine and metabolites of the dopamine in the brain corpus striatum.
Description
technical field [0001] The invention belongs to the field of medicine, and in particular relates to the application of Xinnaoxin capsules in the preparation of medicines for treating Parkinson's disease. Background technique [0002] Parkinson's disease (PD) is the second most common degenerative disease of the central nervous system in humans, and it frequently occurs after the age of 50. The three major clinical manifestations of Parkinson's disease include resting tremor, bradykinesia, muscle rigidity, and posture and gait disturbance. The prevalence of PD in my country is 0.5% among those aged 30 to 60, 1% over 60 years old, and over 5% among people over 80 years old, which has a great impact on the healthy life of the elderly. As the world's population ages, research on the disease has received increasing attention. At present, the commonly used drugs in clinical treatment are levodopa and Madopa, etc., but their application is limited due to their adverse reactions s...
Claims
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IPC IPC(8): A61K36/815A61K9/48A61P25/16
CPCA61K36/41A61K9/48A61K36/185A61K36/815A61K2300/00
Inventor 史公权邹存生马俊仓
Owner 三普药业有限公司
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