Probiotic composition, preparation and use for treating Parkinson's disease REM sleep behavior disorder

A probiotic preparation, a technology for Parkinson's disease, which can be used in drug combinations, medical preparations containing active ingredients, bacteria, etc., can solve the problems of increasing family care pressure, even hallucinations, and aggravating RBD, and achieve good clinical application prospects and Market prospect, reduced dosage, good protective effect
CN111297915BActive Publication Date: 2021-11-23BEIJING FRIENDSHIP HOSPITAL CAPITAL MEDICAL UNIV
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
BEIJING FRIENDSHIP HOSPITAL CAPITAL MEDICAL UNIV
Publication Date
2021-11-23

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Abstract

The invention discloses a probiotic composition for treating rapid eye movement sleep behavior disorder in patients with Parkinson's disease. Made; the number of viable Bacillus licheniformis not less than 10.0×10 8 CFU / g; the number of viable Bifidobacterium longum is not less than 4.0×10 8 CFU / g; the number of viable Lactobacillus acidophilus is not less than 1.0×10 8 CFU / g; the viable count of Enterococcus faecalis is not less than 0.5×10 8 CFU / g. The components of the present invention work synergistically to treat and improve the RBD symptoms and motor symptoms of PD patients, and solve the problem that the existing medicines cannot treat the motor symptoms and non-motor symptoms of PD patients at the same time, and the treatment effect has good sustainability and stability. . The invention effectively reduces the dosage of levodopa for PD patients, prevents patients from developing drug resistance to levodopa prematurely, and has a better protective effect on patients.
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Description

Technical field

[0001] The present invention relates to a probiotic composition, specifically a probiotic composition for the treatment of fast intraoperative sleep behavioral disorders and motion disorders in patients with Parkinson's disease and preparations obtained by the composition. Background technique

[0002] Parkinson's Disease (PD) is a disease in slow pathology, static tremor, and muscle strength, main pathological characteristics is the loss of mid-brain black dopamine neurons and the residual neuronal cytoplasm The body (mainly for the wrong folded α-synaptic nuclear protein) is formed. The clinical manifestations include many non-exercise symptoms, such as constipation, fast-time sleep behavioral obstacles, RBD, olfactory reduction, cognitive impairment, depression, and more.

[0003] Pd is a chronic progressive disease. At present, there are currently such as the treatment of the symptoms of Parkinson 's disease, mainly include the level of the neuronal synaptic g...

Claims

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