383results about How to "Overcoming drug resistance" patented technology

An additive for fowl's feed is prepared from more Chinese-medicinal materials, and can serve to improve immunity, promote appetite and absorption, and relieve inflammation. Its advantages are high effect and low cost.

The invention relates to a bactericidal composition. The bactericidal composition comprises the following active ingredients: A, benziothiazolinone; and B, a methoxyl acrylic ester type bactericide such as kresoxim-methyl, ZJ0712, azoxystrobin, trifloxystrobin, enestroburin and SYP-1620, wherein the mass ratio of the A to the B is 50:1 to 1:50, preferably 10:1 to 1:20, and the balance is auxiliary materials which are allowed and acceptable in pesticide. The composition can be prepared into any formulation suitable for agricultural use by known methods, and the preferable formulations are wettable power, suspension, water dispersible granules and aqueous emulsion. After the combination of the benziothiazolinone and the methoxyl acrylic ester type bactericides, the synergism is obviously achieved, and the bactericidal composition can be mainly used for preventing and controlling deceases of plants such as vegetables, fruit trees, rice and wheat.

The invention relates to a pesticide production and preparation technology, in particular to a sugarcane insecticide. The invention provides a sugarcane insecticide containing a neonicotinoid insecticide, which is prepared into granules or water dispersible granules by mixing the following components in percentage by weight: 0.1-10% of neonicotinoid insecticide, 0.2-15% of organophosphorus insecticide and the balance of assistants, wherein the neonicotinoid insecticide is one of or mixture of any two of thiamethoxam, imidacloprid and thiacloprid; and the organophosphorus insecticide is one or mixture of phoxim and diazinon. When the sugarcane insecticide of the invention is used for preventing and treating sugarcane pests, the sugarcane insecticide has contact poisoning and stomach poisoning functions, has a good systemic conduction function and has a good function of controlling underground and aboveground pests of sugarcane; the sugarcane insecticide which has broad-spectrum insecticidal effects has good effects on preventing and treating sugarcane borers, underground insects, thrips, woolly aphids and the like; the sugarcane insecticide which has a long lasting period can be applied once to effectively eliminate the harm of sugarcane borers in the seedling stage, underground insects, thrips and the like; and the sugarcane insecticide has smaller lethality to natural enemies. The sugarcane insecticide of the invention is used as an important substitute for highly toxic pesticides, has the advantages of low toxicity, high efficiency, safety to people and livestock and is environmental friendly.

The invention discloses a microbial inoculum for preventing the black shank and a preparation method thereof. The classification of production strain of the microbial inoculum is named as bacillus licheniformis GP13, and the preservation number is CGMCCNo.1699. The formulations of the solid medium and the liquid medium of the microbial inoculum are as follows: (1) the formulation of the medium of test tube slant is as follows: 3g of beef extract, 5g of soy peptone, 5g of glucose, 17g to 20g of agar and 1,000ml of distilled water are needed, and the pH is 6.8 to 7.2; (2) the formulation of the medium of liquid fermentation is as follows: 20g of soy peptone, 5g of sucrose, 2g of yeast extract paste, 1g of monopotassium phosphate, 0.02g of ferrous sulfate, 0.02g of zinc sulfate, 0.02g of manganese sulfate, 0.02g of magnesium sulfate, 1,000ml of water, 0.1 percent of peanut oil and 0.01 percent of an antifoaming agent, and the pH is 7.0 to 7.2. The result of the test proves that the invention has good application prospect for preventing the black shack.

The invention discloses a pesticide compound containing penoxsulam and cyhalofop-butyl, and the application thereof; the compound comprises commonly used additive, penoxsulam and cyhalofop-butyl; the weight part ratio of the penoxsulam to the cyhalofop-butyl is 1:1 to 1:20; and the weight percentage of the total weight of the penoxsulam and the cyhalofop-butyl in the pesticide compound is 5 to 80percent. The invention is used for preventing and removing annual grassy weeds in a paddy field. The prevention effect of the invention has significant synergic or adding effect than the single dose,and the invention reduces the used dose of the pesticide, reduces the medication cost, prolongs the service life of the preparation and reduces the adverse impact of the pesticide on the ecological environment.

The invention provides a quaternary ammonium salt grafted guanidine salt bactericide and a preparation method thereof. The preparation method comprises the following steps of: firstly, carrying out polycondensation reaction on polyamine and an inorganic acid guanidine salt under the inertia atmosphere to obtain a polyguanidine salt; mixing long chain alkyl tertiary amine with industrial hydrochloric acid and then reacting the mixture with epichlorohydrin in a hydrophilic organic solvent to obtain a homogenous solution, and removing epichlorohydrin and alcohol solvent remaining in the reaction to obtain a quaternary ammonium salt; and grafting the polyguanidine salt with the quaternary ammonium salt in the hydrophilic organic solvent and a pure water solution to obtain the quaternary ammonium salt grafted guanidine salt bactericide. According to the invention, the main chain of the bactericide is provide with a guanidyl positive ion, and a quaternary ammonium positive ion and tertiary amine are introduced in the side chain of the bactericide, so that the density of the positive charge is enlarged, the bactericidal performance is greatly improved, and simultaneously, the bactericide more easily penetrates through microorganism so that cellular contents overflow, bacteria die and are firmly adsorbed, and durable bactericidal property is better. The bactericide disclosed by the invention can be applied to antimicrobial paper, antimicrobial fiber, and antimicrobial paint industries, daily chemicals industry, washing and sterilization treatment of foodstuff, fruits and vegetables, sterilization and disinfection of wastewater in hospitals and the like.

The invention belongs to the field of medicines, relates to anti-tumor medicines, and in particular relates to anti-tumor medicines in double-aryl urea structures based on indazole, indole, azaindazole or azaindole. The structural formulae of the anti-tumor medicines are shown in formula (Ia) and formula (Ib), wherein Z is N atom or C atom; W is O; M is O, S, N or CH; n is 1 or 2; Y and R are halogen atoms, H, R1, CF3, OCF3, OH, OR2, OCOR3, NH2, NHR4, NR52, NHCOR6, carboxyl group, ester group, cyano group, mercapto group, alkyl sulphanyl, sulfuryl, sulfoxide, sulfonic group, sulfamate, sulfonamide, ketonic group, aldehyde group, nitro group or nitroso group. Pharmacodynamic experiments prove that the medicines have good anti-tumor effects on human lung cancer, human kidney cancer, human colon cancer, human liver cancer, human gastric cancer, human breast cancer, melanoma and the like.

The invention relates to a bactericide composition containing oligosaccharide and copper. The composition is characterized by being prepared from main active ingredients such as oligosaccharide and a copper preparation and pesticide auxiliaries and comprising the following components in percentage by weight: 1-45% of oligosaccharide, 1-50% of copper preparation and the balance of pesticide auxiliaries, wherein the oligosaccharide is one of amino-oligosaccharin (chitosan oligosaccharide), oligogalacturonide acid (pectic oligosaccharide, oligosaccharin) and sodium alginate oligosaccharide; the copper preparation is an inorganic copper or organic copper bactericide; and the dosage form of the bactericide composition can be water agents, emulsion in water, wettable powder, water dispersible granules, suspensions, granules, paste or microcapsule sustained-release agents. The composition has the following beneficial effects: the drug resistance of crops is overcome and delayed; the disease resistance of the crops is improved; the composition can generate synergy together with chemical bactericides; and the composition is safe in application and is safe to the environment and people.

The invention relates to a phage for degrading a Pseudomonas aeruginosa biofilm. The phage is characterized in that: the phage is named C12, the collection number is CGMCC No. 4249, the collection unit is China General Microbiological Culture Collection Center located at No. 3, No. 1 Yard, Beichen West Road, Chaoyang District, Beijing City, and the collection date is October 26, 2010. The invention provides a method for amplifying, separating and preserving the phage for degrading Pseudomonas aeruginosa. The capacity of degrading the Pseudomonas aeruginosa biofilm by the phage is also determined, finally the pure phage C12 with high titer and high biofilm degradation capacity is obtained, and the degradation amount of the pure phage C12 reaches 85.3 percent; the phage can degrade biofilms and crack viable bacteria in the biofilms; the clinical application of the phage can be realized; treatment problems of medicine resistance and biofilms of the Pseudomonas aeruginosa are solved; and the method is a feasible biological method.

The invention relates to an in-tank antiseptic antimildew agent composition integrated with a dry film for paint. The composition is prepared from a water-based paint in-tank antiseptic bactericide, a dry film antimildew agent, a solvent, an aid, a stabilizing agent and water. The in-tank antiseptic antimildew agent composition integrated with a dry film for paint has the advantages of reasonable formula, advanced process, good corrosion and mildew prevention effects, good stability, and the like. When the in-tank antiseptic antimildew agent composition integrated with a dry film for paint is used for paint, salt cluster phenomena can be avoided, an in-tank antiseptic effect can pass a microorganism challenge test, and the dry film mildew-growing grade is a zero grade.

The invention discloses a double-targeting polypeptide-antibody-drug conjugate, and a prepared method and antineoplastic application thereof. The double-targeting polypeptide-antibody-drug conjugate structurally includes four components of (A), tumor specificity targeting polypeptide; (B), an antineoplastic drug; (C), a mitochondria target functional group; and (D), hydrazone bonds used for connecting the polypeptide and the antineoplastic drug. The tumor specificity targeting polypeptide is connected with the antineoplastic drug by a connecting arm comprising the hydrazone bonds; the antineoplastic drug is connected with the mitochondria target functional group by chemical bonds; and the tumor specificity targeting polypeptide is suitable for targeting the conjugate to a tumour cell and marker protein LAPTM4B carried on the surface of the tumour cell is used as a specificity target. A molecular target is combined with an organelle target, selective uptake of the drug in the tumour cell can be increased, an acting site of a DOX drug can be transferred form cell nucleus to mitochondria, and therefore the condition that the tumour cell is killed by drug resistance is avoided.

The invention relates to a traditional Chinese medicine (TCM) oral liquid used for treating animal respiratory tract infection, which includes folium eriobotryae, aster, radix stemonae, fritillaria thunbergii, perilla leaves, bitter almond, ephedra herb, rhizoma pinellinae praeparata, tuckahoe, dried orange peel, asparagus, mustard seeds, radix glehniae, tussilago farfara, bitter orange, semen trichosanthis, radrx peucedani, liquorice and balloon flowers. The medicament is suitable for treating avian respiratory tract infection, such as infectious bronchitis, infectious laryngotracheitis and the like. The formulation of the medicament is combined with the special physiological structures that birds have short genital tract and can not digest lignified fibers to prepare the medicament into oral liquid which can rapidly disperse in feeding water, and then sicken beasts and birds take medicaments by drinking. The TCM oral liquid is convenient, easy to absorb and can achieve the purpose of rapid effect.

The invention provides botanical natural fungicide for fungus. Raw material in the fungicide comprises galic essential oil, plant essential oil mixture, organic solvent, surface active agent and water. The fungicide takes the galic essential oil as the main fungicide, comprises more than two types of other plant essential oil as synergistic agent, and can improve the fungus killing efficiency. The fungicide can still achieve the purpose of preventing and controlling fungal disease in the condition that the use level is reduced through the combination of different chemical compositions of the plant essential oil, and can also prevent the probability that one or more types of chemical compounds produce drug fastness. The fungicide has complex chemical compositions and function groups formed by various chemical compositions, and not only improves the action efficiency and increases the synergic action modes, but also increases the penetrability of the chemical compositions and improves action durability of the combination. The chemical compositions are from natural medicinal plants, innoxious to people and animals, and safe to the environment.

The invention provides a compound expressed by a general formula I, or its pharmaceutically acceptable salt, and an analyzed enantiomer and a purified diastereomer, wherein R<1>is H or C1-12 alkyl groups; R<2> is H, -C(O)R<1a>, -C(O)OR<1a> or -S(O)2R<1b>, wherein R<1a> is H or C1-6 alkyl groups, R<1b> is selected from H or C1-6 alkyl groups halogenated hydrocarbon, phenyl or aryl group; R<3> is selected from C1-4 alkyl groups substituted amino, halogen, hydroxyl, sulfydryl, guanidyl, nitryl or cyano group; and R<4> is -(CH2)nCO2H, -(CH2)nP(O)(OH)2, -(CH2)nCO2R<1a> and -(CH2)nP(O)(OR<1a>)2, wherein R<1a> is H or C1-6 alkyl groups, n is an integer between 0 and 4, or a salt of the above groups. The invention also provides a preparation method of the cyclohexene compound expressed by the general formula I, and an application of the cyclohexene compound taken as an influenza virus neuraminidase inhibitor for preparing the medicines to prevent or treat the influenza diseases.

The invention discloses a piglet health protection fodder comprising the following components in parts by weight: 10-15 parts of traditional Chinese medicine additives, 5-10 parts of a fishy smell product, 10-20 parts of a chemical addition agent and 2,000-3,000 parts of fodder body powder. The invention also discloses a preparation method of the health protection fodder. The preparation method comprises the following steps: smashing the traditional Chinese medicine additives, preparing the fishy smell product, preparing the fodder body powder, adding the prepared traditional Chinese medicine additives, the fishy smell product and the chemical addition agent into the fodder body powder, and uniformly stirring to prepare fodder particles. The health protection fodder has the effects of clearing away heat and toxic materials, diminishing inflammation, sterilizing, enhancing immunity of the organism, tonifying spleen, promoting appetite, aiding digestion, facilitating absorption of good nutrition elements and promoting growth on piglets.

The invention belongs to the field of drugs, and relates to an antineoplastic drug, particularly an indazole / azaindazole-based diarylcarbamide / thiocarbamide-structure antineoplastic drug. The structural general formulae of the indazole / azaindazole-based diarylcarbamide / thiocarbamide-structure antineoplastic drug are disclosed as Formula (Ia) and (Ib), wherein Z is an N or C atom; W is an atom or group, such as O, S, NH, NOH, NCH or the like; M is O, S, N, CH or the like; n is 1 or 2; and Y and R are respectively halogen atom, H, R1, CF3, OCF3, OH, OR2, OCOR3, NH2, NHR4, NR52, NHCOR6, carboxy group, ester group, cyano-group, sulfhydryl group, alkylthio group, sulfuryl group, sulfoxide group, sulfo-group, sulfonate group, sulfamide group, ketone group, aldehyde group, nitro-group or nitroso-group. The pharmacological experiment proves that the drug has favorable antineoplastic effect on human lung cancer, human kidney cancer, human colon cancer, human liver cancer, human stomach cancer and human breast cancer.

The invention relates to a preparation method for a microbial organic soil bactericidal and insecticidal warming conditioning agent. Fermentation raw materials are domestic fungus cultivation residue substances, the fermentation raw materials are crushed and added with water, and thus the water content mass percent of the fermentation raw materials is 25-35%; decomposing inoculants are added at a mass ratio of1:1000, the mixture is mixed uniformly, the fermentation raw materials mixed with strains are added with tourmaline powder with a mass percent of 5%, rare earth negative ion powder with a mass percent of 2%, composite biological insecticides accounting for 1% of the finished product total mass and composite biological bactericides accounting for 1% of the finished product total mass, the mixture is mixed uniformly, then loose packing or granulation is carried out, drying is carried out and the water content is 10%; packaging is carried out, and a microbial organic soil bactericidal and insecticidal warming conditioning agent is prepared. The produced conditioning agent is advantageous in that the organic matter content is high, the ground temperature is raised, absorption of phosphor and potassium for crops can be raised, the conditioning agent has functions of preventing soil borne diseases, releasing phosphorus and potassium, fixing nitrogen and killing nematodes and green environmental protection is achieved.

The present invention relates to a plant acaricide applied to controlling the mite on the economic crops such as the fruit trees and the vegetables and a preparation method and a usage of the plant acaricide, which is made by adding the surfactant, the emulsifying agent, the penetration agent and the synergist into the effective part of walnut green hull of Juglans regia L.. The present invention is characterized in that the plant acaricide has high efficiency, low toxicity and fewer residues and is friendly to the environment.

A paper able to kill and suppress bacteria features that it contains the crystal whickser of zinc oxide as the bacteria killing and suppressing material. Its preparing process and its application in culture, medicine, cigarette, food, etc. and also disclosed.

The invention provides a plant-source natural fungicide for preventing and controlling botrytis cinerea, which comprises the following raw materials: garlic essential oil, a plant essential oil mixture, an organic solvent, a surfactant and water. The garlic essential oil servers as the main fungicide, and more than two other plant essential oils serve as synergists, thus the efficiency of killing the botrytis cinerea can be improved. Due the combination of different chemical components of the plant essential oils, even under the condition of reducing the use amount, the purpose of preventing and controlling the botrytis cinerea can still be achieved, and the resistance to the plant-source natural fungicide of one or more compounds can be prevented. The plant-source natural fungicide comprises complex chemical components and also comprises functional groups formed by several kinds of chemical components, thus the efficiency of fulfiling the function of the plant-source natural fungicide is enhanced, the synergistic forms are increased, the permeability of the chemical components is improved, and the compound can take effect on the crops for a long time. Because the chemical components of the plant-source natural fungicide are natural medical plants, the plant-source natural fungicide is not-toxic to humans and animals and is safe to environment.

The invention discloses a bacillus subtilis microbial agent for preventing and curing alternaria alternate. The production bacterial strain of the microbial agent is classified and named as the Bacillus subtilis B75 with the preservation number CGMCC No.1700. The bacterial strain is moved to the inclined culture medium of a test tube and cultured with a constant temperature 30 DEG.C+ / -1 DEG C for 1-2 days to obtain a test tube strainThe test tube strain is cultured by means of liquid shake-flask fermentation for 30-36 hours to obtain liquid fermenting microbial agent or solid microbial agent. The experiment indicates that the microbial agent as a good application prospect for preventing and curing the alternaria alternate.

The invention relates to a trapping medicine of termites and a termites trapping method thereof. The soil termites trapping medicine comprises the following components by weight percent: 40 to 50 percent of moli eucalyptus bark, 40 to 50 percent of macrophyll eucalyptus bark, 5 to 10 percent of soil termites active hormone, 1 to 3 percent of fipronil, and 1 to 3 percent of sulfluramid. The invention can avoid the drug resistance of the termites and enhance the trapping effect action obviously and has the advantages of strong trapping capability for the soil termites, uneasy mouldness, extensive source, low cost, no damage risk on crops and easy generalization. The soil termites trapping method comprises the following steps that: the medicine powder manufactured through the prescription is packed with coarse paper and is placed in a degradable plastic box to manufacture a soil termites trapping box. The trapping box is buried at the place the soil termites move frequently and the middle of the dense grouping holes when the grouping holes are formed and before the grouping is carried out. The invention has the effects of uneasy water leakage, low labor cost and ideal prevention and treatment effect.

The invention discloses a broiler feed, which comprises the following active ingredients in parts by weight: 20-30 parts of traditional Chinese medicine additives, 5-10 parts of a fishy product, 10-20 parts of a chemical additive, and 2,500-3,000 parts of feed body powder. The invention further discloses a preparation method of the feed. The preparation method comprises the following steps: grinding the traditional Chinese medicine additives, preparing the fish product and the feed body powder, adding the prepared traditional Chinese medicine additives, the fish product and the chemical additive into the feed body powder, and evenly stirring to obtain feed granules. The feed has the effects of clearing away heat and toxic materials, diminishing inflammation and sterilizing, strengthening the organic immunity, tonifying spleen and promoting appetite to aid digestion, facilitating the absorption of beneficial nutrition elements, and promoting the growth of broilers.

The invention provides a formula of a pesticide for preventing and treating sugarcane moth borer and a production method for the pesticide formula and belongs to the technical field of pesticides. The pesticide formula is characterized by consisting of the following raw materials in parts by mass: 30-50 parts of monosultap, 20-30 parts of chlorpyrifos, 1-3 parts of a wetting agent, 2-5 parts of a dispersion agent, 1-1.5 parts of an anti-blocking agent, 0.01-0.05 part of a defoaming agent, 0.5-1 part of suspending agent and 25-30 parts of filler. The production method of the pesticide product comprises the following steps of: stirring and mixing the raw materials, smashing the raw materials through air flow and then fully mixing the raw materials. The pesticide of the formula is uniformly sprayed on leave surfaces of sugarcanes after being diluted by 500-800 times of water, so that borer pests on the sugarcanes in a seedling stage and the sugarcane stalk borer pests in the later stage can be effectively controlled; the prevention and treatment effect is over 85 percent; furthermore, sugarcane cottony aphids can be also prevented. The main active components, namely the monosultap and the chlorpyrifos, of the product disclosed by the invention have different working modes and are high in complementarity, so that the synergism effect is obvious; the drug resistance of pests can be overcome, the prevention and treatment effect can be enhanced, the drug use frequency and the using amount of the pesticide are reduced, and the production cost is reduced.

The invention relates to a botanical fungicide used for controlling the powdery mildew and gray mold of fruit trees and vegetables, in particular to a compounded fungicide containing zincpolyanemine and ethylicin, and pertains to the technical field of pesticides. The active ingredients of the fungicide are the zincpolyanemine and ethylicin with the weight ratio of 1:2 to 5:1. In the preparation ingredients of the fungicide, the ethylicin and the zincpolyanemine totally account for 5 percent to 60 percent of the weight of the preparation agents, grass vinegar accounts for 5 to 20 percent of the gross weight of the fungicide, addition agents (surfactant, wetter) account for 5 to 10 percent of the gross weight of the fungicide, and the rest is fillers. The invention utilizes the synergy of the zincpolyanemine and ethylicin to make up for the own deficiency of single-dosage pesticide, thus overcoming the pesticide resistance of diseases and improving the pesticide application effect. Through practical test, the fungicide has remarkable control efficiency to the powdery mildew and gray mold of fruit trees and vegetables, with high efficiency, safety and environment protection.

The invention discloses a production process for a bamboo charcoal polyester staple fibre. In the production process, regenerative PET (Polyethylene Terephthalate) material is used as the material, and the finished product is acquired by pre-treating, rotary drum drying, melt spinning, cooling and forming, winding, drafting, curling, oil applying, thermosetting and cutting-off in sequence, wherein the rotary drum drying comprises the steps of firstly drying the regenerative PET material for 5.5h-6.5h and then adding bamboo charcoal master batches with the final mass fraction of 6%-8% and including bamboo charcoal with the mass fraction of 22%-27%; and the total drying time is 9.5h-10.5h; both the screw rod and the spinning beam of a screw extruder in the melt spinning step are at the temperature from 278 DEG C to 282 DEG C; cooling forming is realized through circular air blow, the temperature of the circular air is 22 DEG C to 26 DEG C, and the air velocity of the circular air is 4.0m / s-5.0m / s; the total draft multiple is 3.1-3.3 times; and the thermosetting temperature is 162 DEG C to 168 DEG C, and the thermosetting time is 13 minutes to 17 minutes. The production process can save the cost and is helpful for environmental protection; the produced product has a better smooth and comfortable hand feeling and moisture-absorption air permeability than those of a normal polyester staple fibre.

The invention relates to the technical field of duck breeding, in particular to an anti-epidemic device for duck breeding. The anti-epidemic device comprises a box body, the inner side of the box bodyis fixedly connected with a feeding device, the feeding device comprises a first motor, the first motor is embedded on the inner side of the top end of the box body, and an eccentric wheel is fixedlyconnected to the tail end of a spindle of the first motor. The inner side of the top end surface of the box body is fixedly connected with a fixed plate bilaterally symmetrical, the inner side of thefixed plate is in sliding connection with a movable rod, one end of the movable rod is fixedly connected with a first spring, the other end of the first spring is fixedly connected with the box body,the top end of the movable rod is fixedly connected with a limit block, and the top end of the movable rod is fixedly connected with a check block. By means of the eccentric wheel, the movable rod, the limit block and the check block, a feed and medicine can be fed conveniently and mixed in a certain proportion, the immunity of ducks can be improved, and the probability of the ducks to get sick is reduced. The device is capable of achieving feeding simply and conveniently.

The present invention relates to the recipe and preparation process of botanical composite pesticide for preventing and killing pests of crop. The effective components of the botanical composite pesticide are Langdu toxin, tagettin and rutarin.

The invention discloses a method for manufacturing an environment-friendly insecticide with nerium indicum and radix euphorbiae lantu. The method includes manufacturing nerium indicum extracts, to be more specific, cleaning and airing fresh nerium indicum leaves, cutting the nerium indicum leaves to obtain fragments, drying the fragments in drying ovens, smashing the fragments, mixing the fragments and ethanol with one another to obtain mixtures, then processing the mixtures by the aid of microwave, then soaking the mixtures for 48h, then filtering the mixtures, extracting nerium indicum leaf extracts from the mixtures and carrying out water-bath distillation to recycle the ethanol; manufacturing radix euphorbiae lantu extracts, to be more specific, cleaning and airing fresh radix euphorbiae lantu, cutting the radix euphorbiae lantu to obtain fragments, drying the fragments in drying ovens at the temperatures of 60 DEG C, then smashing the fragments, mixing the fragments and ethanol with one another to obtain mixtures, then processing the mixtures by the aid of microwave, then soaking the mixtures for 50h, then filtering the mixtures, extracting the radix euphorbiae lantu extracts from the mixtures and carrying out water-bath distillation to recycle the ethanol; uniformly mixing the nerium indicum extracts and the radix euphorbiae lantu extracts with one another according to a proportion of 3:1 to obtain mixtures, and then adding antibiotics into the mixtures for preservation.

The invention relates to a plant acaricide for preventing and treating acarid on cash crops such as fruit tree and vegetable, and its preparation method and application. The acaricide is prepared from active components of Juglans regia leaf, surfactant, emulsifying agent, penetrant, and synergist; and has high efficiency, low toxicity, low residual, and no enviromental pollution.