60results about How to "Overcome toxicity" patented technology

The invention provides methods and compositions for performing a stringent wash step in a hybridization assay between at least one molecule and a target. The invention may, for example, eliminate the use of, or reduce the dependence on formamide in the stringent wash step. Compositions for use in the invention include an aqueous composition comprising at least one polar aprotic solvent in an amount effective to denature non-complementary sequences in a hybridization product.

The invention discloses an endotoxin adsorbent using a molecular cluster as a functional group and a preparation method thereof, and belongs to the fields of bioseparation and biomedical engineering. By taking agarose gel as a vector, the endotoxin adsorbent is subjected to epoxy activation to be directly coupled with a molecular sieve frame epsilon-polylysine or polyaspartic acid, then the coupled mixture is ingrafted with micromolecular lysine or lycine by virtue of a condensation reaction to prepare the adsorbent. The adsorbent prepared by the method has higher removal rate to endotoxin in serum of a human, but adsorbs less serum protein. Meanwhile, the preparation process of the adsorbent has the advantages of mild conditions, fewer synthesis steps and relatively low material cost.

The invention provides a selenium-rich natural hygienic dairy product, wherein the newly screened bacterial is utilized to ferment the inorganic selenium, so as to transform into safe, highly effective feed addictive containing biologically active selenium. Milk with high selenium content can be produced through feeding the cows in milk with the additive.

The invention relates to a method for preparing black zirconia ceramics at low temperature, and belongs to the technical field of high-temperature structural material preparation. Said method uses homogeneous precipitation method to synthesize nanometer coloring agent and co-precipitation method to synthesize nanometer zirconia powder, and adopts Fe-Co-Ni-Mn as colorant. Do not add any sintering aids to the zirconia powder, only add a small amount of coloring agent, and sinter at 1150-1350°C to obtain black zirconia ceramics with excellent performance and bright color. Because the invention adopts the homogeneous precipitation colorant powder, monodisperse nano particles with uniform particle size, narrow size distribution and high purity are obtained, so that the colorant is easy to color. Co-precipitation is used to synthesize zirconia powder to obtain nanoparticles with small particle size, large surface area and high activity, which can reduce the temperature of solid-phase reaction, greatly reduce the sintering temperature, and solve the problem of high-temperature decomposition and volatilization of black colorant oxides. At the same time, the present invention adopts Fe-Co-Ni-Mn as the coloring agent, which avoids the toxic effect of Cr on the human body.