Composite antimicrobial liquid soap and preparation method thereof

Abstract

The invention relates to a preparation method of a composite antimicrobial liquid soap, which comprises the following steps: adding 0.2-0.6g of olive leaf extract into water at 22-28 DEG C, stirring uniformly, adding 20-30ml of glycerol, adding deionized water to 70-80ml, heating to 45-50 DEG C, oscillating at constant temperature for 8-12 hours, cooling to 22-28 DEG C, adding 20-30ml of 98-99.7 wt% ethanol and 0.05-0.1g of triclosan, stirring uniformly, and regulating the pH value to 6-8, thereby obtaining the composite antimicrobial liquid soap, wherein the mass content of the olive glycoside in the olive leaf extract is 30-40%. The invention also relates to a composite antimicrobial liquid soap. The composite antimicrobial liquid soap has the advantages of no toxicity, high antimicrobial property, favorable volatility, high stability and skin care.

Description

technical field [0001] The invention relates to a hand sanitizer, in particular to a composite antibacterial hand sanitizer and a preparation method thereof. Background technique [0002] Epidemiological and epidemiological studies have found that most infectious diseases can be mediated through hands as a transmission route. In addition, the hands of hospital medical staff are an important cause of nosocomial infections. Therefore, reasonable hand disinfection is the key to controlling nosocomial infections and infections. important method of disease transmission. [0003] In the past, people used soap as a hand washing product. Soap has the characteristics of poor usability and serious cross-contamination, which easily leads to secondary pollution. At present, soap is gradually being replaced by hand sanitizers in public places. Hand sanitizers have the function of cleaning and skin care, and adding specific ingredients in them can play a role in disinfection and sterili...

AI Technical Summary

Problems solved by technology

[0005] At present, most of the disinfectant hand sanitizers in hospitals, hotels and toilets use chemical disinfectant ingredients, such as chlorhexidine acetate, 75% ethanol, H 2 o 2 Or benzalkonium chloride, etc., which are highly irritating to the skin, especially for hospital medical staff who need to use it repeatedly for a long time, which will cause damage to the skin of the hands, such as chapped, peeling and dermatitis, and even induce diseases through skin absorption

At present, there are few hand sanitizers containing plant ingredients. The main reason is that most of the plant ingredients are active ingredients extracted by alcohol and organic solvents, which are not easily soluble in water and easy to form precipitates, which will affect the product properties of hand sanitizers. In addition, the active ingredients of non-edible plants often have certain toxicity, which is easy to induce allergies and other hazards

[0006] In summary, in the prior art, most of the pure Chinese herbal medicine extracts have poor solubility in water, and are generally made to be easier to precipitate, which has a greater impact on product properties, and the antibacterial ability of simple plant extracts is relatively poor, and generally can only achieve antibacterial properties. The effect of bacteria, it is difficult to achieve a short-term bactericidal effect

Synthetic antibacterial agents have strong bactericidal ability, but ethanol and other disinfectants such as chlorhexidine, iodophor, and benzalkonium bromide are too high in content, which can easily cause skin irritation and toxicity