57 results about "Olea europaea leaf extract" patented technology

This invention discloses a method for preparing olea leaf extract rich in high-purity oleuropein. The method comprises: extracting olea leaves with polar solvent, centrifuging to obtain the supernatant and the precipitate, performing composite membrane separation to obtain concentrated solution passing through the nanofiltration membrane, adsorbing with an adsorption medium, eluting the adsorption medium to obtain the eluate, vacuum-concentrating, and freeze-drying or spray-drying in vacuum to obtain olea leaf extract rich in high-purity oleuropein (more than 50%). The method adopts composite membrane separation and medium adsorption techniques to replace traditional solvent extraction technique, thus can increase oleuropein purity, save energy and eliminate pollution. The polar solvent can effectively extract oleuropein, and the nonpolar solvent can effectively remove liposoluble substances, thus is advantageous for increasing oleuropein yield and purity.

A process for preparing the extract of olive leaf includes such steps as low-temp drying in dark condition, pulverizing, extracting in ethanol or methanol by reflux, immersing, seeping, or ultrasonic wave, filtering, vacuum concentrating, vacuum drying to obtain coarse extract, pulverizing, sieving, dissolving in water, filtering, membrane separation, and purifying by ion exchange.

The invention discloses a method for preparing high-purity hydroxytyrosol by using high-speed counter-current chromatography and high performance liquid chromatography in a combined manner. The method comprises the following steps of performing enzymolysis on an olive leaf extract; extracting with ethyl acetate and concentrating into hydroxytyrosol ointment of which hydroxytyrosol content is 5%-20%; mixing solvents such as petroleum ether, ethyl acetate, methanol and water proportionally; using the mixture as a high-speed counter-current solvent system under the condition that an upper phase is a fixed phase while a lower phase is a mobile phase; dissolving the hydroxytyrosol ointment in the lower phase to obtain a test article; fully filling multilayered coil separating columns of a high-speed counter-current chromatographic instrument in the fixed phase; injecting the mobile phase at revolving speed of 500-1800 r / min and at flowing speed of 1-5mL / min; and detecting by using an ultraviolet detector of which the wave length is 210-280 nanometers. Normal phase centrifugal rotation is implemented in a whole centrifugal process for 30-300 minutes. When the mobile phase begins to flow out of chromatographic columns, distillate is collected, and after the distillate is detected by HPLC (high performance liquid chromatography), the hydroxytyrosol of which the purity is 60-90% can be prepared. The method is easy to operate and low in pollution; and the purity of the separated hydroxytyrosol is high.

The invention discloses a novel method for rapidly preparing hydroxytyrosol and belongs to the technical field of extraction and separation of active ingredients of natural products. According to the novel method, the olive leaf extract containing oleuropein serves as a raw material, and hydroxytyrosol is prepared by rapid hydrolysis under alkaline conditions. The method comprises the following steps: weighing a certain amount of olive leaf extract, mixing with an alkaline solution, reacting under a certain temperature and time, cooling to room temperature, adding a little amount of acid to neutralize until the pH is equal to 7, centrifuging, collecting the supernatant fluid, adding a proper amount of ethyl acetate for extracting, performing rotary evaporation to remove ethyl acetate, sequentially allowing the obtained concentrated solution to pass through macroporous resin and sephadex resin, and finally carrying out spray freeze-drying or vacuum freeze-drying to obtain high-purity hydroxytyrosol. The purity can be up to over 90 percent. The novel method is easy to operate, short in time, high in efficiency, high in quality and suitable for industrialization.

The invention belongs to the field of cosmetics and discloses a hair conditioner comprising olive oil and derivatives of the olive oil and a preparation method of the hair conditioner. The hair conditioner comprises the following raw material components in percentage by mass: 1 to 3 percent of olivamidopropyl trimethylammonium chloride, 1 to 10 percent of olive (OLEAEUROPAEA) fruit oil, 1 to 5 percent of sorbitan olivate, 1 to 5 percent of polydimethyl siloxane, 1 to 8 percent of PEG-7 olivate, 0.1 to 1 percent of plant sterol ester, 1 to 10 percent of an olive leaf extract, 0.1 to 1 percent of a preservative, 0.05 to 1 percent of essence, 0.01 to 0.5 percent of pH regulator and the balance of deionized water. Over 90 percent of components in the formula are naturally sourced components, the product is natural, mild and almost nonirritant, can be used for a long time, can be used for nursing dry and damaged hair and can be used for daily care.

The invention provides multi-effect moisturizing cream. The multi-effect moisturizing cream is prepared from the following components in parts by weight: 0.01 to 3 parts of butterflybush flower extract, 0.01 to 2 parts of vaccinium myrtillus fruit extract, 0.01 to 2 parts of xanthan gum, 0.01 to 2 parts of citric acid, 0.01 to 2 parts of gluconolactone, 0.01 to 2 parts of calcium gluconate, 0.01 to 5 parts of hylocereus undatus fruit extract, 0.01 to 5 parts of phenoxyethanol, 0.01 to 5 parts of sodium pyrosulfite, 0.01 to 3 parts of leucojum aestivum bulb extract, 0.01 to 3 parts of olive leaf extract, 0.1 to 3 parts of nicotinamide, 0.01 to 2 parts of punica granatum fruit extract, 0.01 to 2 parts of dipalmitoyl hydroxyproline, and 0.001 to 0.5 part of eryngium maritimum callus culture filtrate. By virtue of the compounding of ingredients in the formula, the moisturizing cream provided by the invention has multiple efficacies such as moisturizing, blue light resistance, restoration,wrinkle resistance, whitening, speckle removal and the like.

A composition for treating herpes and cold sores. The composition may be topically applied, ingested into the body, or injected into the body. The composition may be applied quickly and discretely in order to sooth and treat herpes and cold sores. The composition utilizes a highly effective combination of compounds, including olea europaea leaf extract and olea europaea fruit oil, to achieve this end.

The invention discloses anti-inflammatory soothing emulsion. Natural active ingredients such as a mangosteen extract, tea saponin, a purslane herb extract and an olive leaf extract are added into theemulsion, so that the emulsion not only is safe and mild, but also can efficiently exert an anti-inflammatory soothing effect, wherein the mangosteen extract can assist in enhancing skin antioxidant capacity, relieving inflammation and inhibiting allergic reaction of skin; the tea saponin has obvious bacteriostatic and antibacterial effects, and helps to ease skin and reduce itching feeling of skin; the purslane herb extract can scavenge free radicals and further assist in easing the skin; and the olive leaf extract has good anti-inflammatory and bacteriostatic effects. The active ingredientsact synergistically to play a better role in inhibiting bacteria, diminishing inflammation and improving anti-oxidation of organisms, and can ease skin, increase skin comfort, promote skin repairing and maintain skin health.

The invention discloses a moisturizing cream containing natural olive oil and derivatives of olive oil, and a preparation method of the moisturizing cream, falling into cosmetic field. The cream comprises1-12% of olive oil, 1-10% of decyl olivate, 1-10% of ethylhexyl olivate, 1-3% of cetearyl olivate, 1-3% of sorbitan olivate, 1-5% of PEG-7 olivate, 0.1-10% of olive leaf extract, 0.1-0.5% of allantoin, 0.05-0.5% of dipotassium glycyrrhizinate, 0.05-1% of preservative, 0.05-0.5% of essence, 0.1-2% of thickener, 0.05-1% of pH regulator, and the balance of deionized water. The moisturizing creamadopts natural ingredients, is mild and has no irritation, can be used in long term to moisturize and care skin, is used for daily caring and has good effects for both dry and sensitive skin.

The invention relates to a method for separating high-purity oleuropein by utilizing counter-current chromatography. According to the method, an ethanol solution is adopted to extract an olive leaf extract, and then the olive leaf extract is separated by using the counter-current chromatography as a separating means. The method comprises the steps that n-butyl alcohol, ethyl acetate, methanol and water are prepared into solvent systems of a flow phase and a fixed phase; the separation column of a counter-current chromatograph is fully filled with the fixed phase, and the flow phase is pumped to achieve two-phase balance; after sample feeding of a sample feeding valve, the flow phase is eluted; a target component is collected according to a detector's graph and combining HPLC detection; an oleuropein monomer compound is obtained after fractions containing the oleuropein are mixed and solvents are recovered. By adopting the method, the oleuropein compound having the purity 90% or above can be obtained. The method is simple, convenient and fast, a separating effect is good, the preparation amount is large, sample loss is small, the separating cost is low, the product purity is high, and the whole separating method is suitable for industrial production.

The invention relates to a method for separating high-purity oleuropein by combining macroporous resin and preparative liquid chromatography. By adopting the method, an oleuropein compound having the purity of 90% or above can be obtained. The separation cost of the method is low, the preparation process is safe, the oleuropein having the purity of 90% or above can be rapidly separated and prepared from an olive leaf extract by combining the macroporous resin and the preparative liquid chromatography, and the whole separating method is suitable for industrialized production.

The invention relates to a facial mask congealed fat containing dendrobium officinale polysaccharide and a preparation method thereof. The facial mask congealed fat is prepared from dendrobium officinale polysaccharide silk protein, seaweed extract, aloe extract, chlorophyll, cucumis sativus extract, ganoderma lucidum extract, fiddlehead root extract, olive leaf extract, fennel seed extract, camellia oil extract, ginkgo leaf extract, poplar flower extract, beta-glucan, sodium cocoyl isethionate, shea butter, triglyceride, dendrobium officinale essence, disodium lauryl sulfosuccinate, sodium coco-sulfate, wheat starch, paraffin, titanium dioxide and a proper amount of distilled water according to a specified weight proportion. The facial mask congealed fat which has the advantages of high softness and toughness, and effects of moisturizing and protecting skin can be prepared under the condition of no adding of a modifier, the polysaccharide prepared from dendrobium officinale, so that the effects of moisturizing and protecting skin, and relieving the skin are achieved.

The invention discloses a soluble microneedle for removing acne. The microneedle comprises the following effective components in parts by weight: sodium shale oil sulfonate, an oregano leaf extract product, a thyme extract product, a bark extract product of Cinnamomum zeylanicum, a leaf extract product of olive, a leaf extract product of rosemary, a leaf extract product of Mentha piperita, a flower extract product of lavender, an extract product of Hydrastis canadensis, and an extract product of citron pericarp. The product is advantageous in that various anti-acne medicaments are highly selected and optimally combined, dosage as well as toxic and side effects of each medicament are minimized, and safety scope and usage scope are enlarged; the product can improve metabolism of skin and surrounding microenvironment of skin, acne is removed fundamentally, scars are removed without relapse, and the product is easy to produce, transport and store with reduced cost.

The invention discloses a preparation method of water-soluble olive polyphenol with bacteriostatic and preserved activity on meat products, and the preparation method comprises the following steps of; screening fresh olive leaves, drying, and crushing into powder less than 0.5 cm; extracting in twice at 50-100 DEG C for the boiling time of 10-60 minutes, wherein the solid-to-liquid ratio of dried olive leaves and different extraction solvents is 1:(6-30); filtering, merging extracting solutions, decompressing, concentrating, and then carrying out vacuum freeze drying to prepare different extracts, wherein the water content of the solid powder is less than 10%; then carrying out resin purification and solvent extraction, adding 1-5 percent by weight of water-soluble beta-cyclodextrin to the extracts, and carrying out vacuum drying to prepare 60%-90% olive polyphenol powder. The olive leaf extract prepared through the method disclosed by the invention has the inhibition zone average value of 1.5-3.50 cm on Staphylococcus aureus and the inhibition zone average value of 1.20-3.20 cm on escherichia coli under the concentration of 1%-20%, can be used for treating the fresh meat and the braised pork by achieving the mass ratio of the olive extract and the meat products to 0.1%-5%, can be used for prolonging the shelf life of preservation in air for 3-5 days at 0-15 DEG C and prolonging the shelf life of preservation under vacuum packaging for 10-30 days at 0-15 DEG C.

The invention relates to a preparation method of a composite antimicrobial liquid soap, which comprises the following steps: adding 0.2-0.6g of olive leaf extract into water at 22-28 DEG C, stirring uniformly, adding 20-30ml of glycerol, adding deionized water to 70-80ml, heating to 45-50 DEG C, oscillating at constant temperature for 8-12 hours, cooling to 22-28 DEG C, adding 20-30ml of 98-99.7 wt% ethanol and 0.05-0.1g of triclosan, stirring uniformly, and regulating the pH value to 6-8, thereby obtaining the composite antimicrobial liquid soap, wherein the mass content of the olive glycoside in the olive leaf extract is 30-40%. The invention also relates to a composite antimicrobial liquid soap. The composite antimicrobial liquid soap has the advantages of no toxicity, high antimicrobial property, favorable volatility, high stability and skin care.

The invention discloses an anti-allergic mask containing an olive leaf extract. The anti-allergic mask is prepared from: (1) mask base cloth and (2) mask essence, wherein the mask essence is prepared from the following raw materials: (a) a water-soluble thickener, wherein the thickener enables the mask essence to have the viscosity of 1mPa.s-5000 mPa.s; (b) 0.1wt%-20wt% of humectant, wherein the humectant is prepared from polyalcohol and beta-glucan; (c) 0.1wt%-10wt% of anti-allergic composition, wherein the anti-allergic composition is prepared from 4-tert-butyl cyclohexanol and the olive leaves extract; (d) a water-containing carrier. The anti-allergic mask can relieve the neurosensory activity of a sensitive skin symptom and improve the immunity of the skin, and has double anti-allergic effects.

The invention discloses an anti-pollution cream and a preparation method thereof. The anti-pollution cream comprises polyglycerol-10 stearate, glyceryl stearate, PEG-100 stearate, cetearyl alcohol, cetyl palmitate, macadamia nut oil, caprylic / capric triglyceride, mineral oil, polydimethylsiloxane, squalane, tridecyl alcohol trimellitate, xanthan gum, nicotinamide, 1,3-butanediol, glycerin, carboxymethyl chitosan, maltooligosyl glucoside, hydrogenated starch hydrolysate, emulsifier, plant extract, phaeodactylum tricornutum extract, citric acid, sodium hydrogen sulfite, fructan, decylglucoside,olive leaf extract, jujube extract, sea haricots frond extract, cactus fruit extract, phenoxyethanol, ethylhexyl glycerol and pure water. The cream can improve the self-protection and repair capability of the skin, resist pollution and reduce the damage to the skin caused by air pollution.

The invention discloses ice cream-shaped scrub cream with an acne removing effect. An acne-removing composition is added into the scrub cream, and is prepared by compounding a plurality of plant extracts and has the effects of synergistic interaction, bacteriostasis, resisting inflammation, controlling grease secretion, relieving acne redness and swelling symptoms, assisting in acne skin healing and fading acne marks. The acne-removing composition comprises the following components in percentage by mass: 0.1-0.3% of totarol, 0.5-5.0% of a PEUMUS BOLDUS leaf extract, 0.1-1.0% of an OLEA EUROPAEA leaf extract and 1.0-3.0% of an EPILOBUM ANGUSTIFOLIUM flower / leaf / stem extract.

The invention discloses sunset abelmoschus root-olive toothpaste which comprises, in weight percentage, 1.5% of sunset abelmoschus extract, 0.5% of olive leaf extract, 20-35% of moisturizers, 1.0-3.0% of binders, 15-30% of friction agents, 1.5-3.0% of foaming agents, 0.2-0.6% of sweetening agents, 0.02-0.07% of antioxidants and the balance deionized water, wherein the extract is crushed into 100 meshes. A preparation method of the sunset abelmoschus root-olive toothpaste includes the steps: (1) preparing the sunset abelmoschus extract; (2) preparing the olive leaf extract; (3) mixing raw materials. Compared with the prior art, the sunset abelmoschus root-olive toothpaste has the advantages that the sunset abelmoschus extract and the olive leaf extract are compounded, pure natural Chinese herbal medicine raw materials are used, functional components of the raw materials can be effectively improved, and the toothpaste has inflammation diminishing and pain easing functions, has remarkable curative effects on gingival bleeding, gingival pain and swelling and the like, does not contain any preservatives and is safe in long-term use and free from any toxic and side effects.

The invention discloses a pharmaceutical composition for resisting diabetes activity and a preparation method thereof. The composition is composed of an olea europaea leaf extract and a carrier, wherein the carrier is selected from starch, beta-cyclodextrin, a talcum powder, microcrystalline cellulose and magnesium stearate. In-vitro cell glucose consumption experiments prove that the composition increases the glucose consumption amount of model cells and has obvious hypoglycemic effect. In-vivo animal experiments prove that the composition has a significant role in lowering blood glucose on mesoxyalyurea induced hyperglycemic mice.

The invention provides a repairing and aging resistance compound containing multiple plant extracts, a preparation method and application. The repairing and aging resistance compound containing multiple plant extracts is prepared from, by mass, 1%-10% of a moisturizing agent, 3%-10% of a repairing and aging resistance agent, 0.1%-5% of a preservative and the balance deionized water. The olive leafextract and the centalla asiatica extract are cooperatively used and can achieve a synergistic effect, the epidermal barrier capacity is effectively improved, the damaged skin is effectively repaired, and aging resistance is effectively improved. It is proved through an experiment result that cooperative use of the two extracts can achieve the best use effect.

The invention discloses a facial mask with the skin grease balancing effect. The facial mask comprises diatom ooze fiber facial mask cloth and facial mask essence fluid. The facial mask essence fluidcomprises grease-control active matter, wherein the grease-control active matter is composed of royal jelly, hydrolyzed olea europaea leaf extract, and epilobium fleischeri extract. It is proved by tests that the obtained facial mask in the embodiment of the facial mask with the skin grease balancing effect has the good instant and long-acting grease-control effect.

The invention discloses a preparation method of olive leaf extract. The microwave-assisted solvent extraction method only needs a very short time, and the extraction efficiency is high. Moreover, due to the much shorter extraction time, the properties of high-temperature sensitive substances will not change after extraction. Smaller, the use of macroporous adsorption resin separation can enrich the active substances in the extract, improve the selectivity and stability of the extract, reduce the factors that affect the activity of the extract, and maintain the activity of the extract.

The invention belongs to the field of cosmetics, and relates to a composition with effects of controlling oil, tendering skin and shrinking pores as well as a preparation method and application of thecomposition. The composition comprises a honey extract, a fig extract and an olive leaf extract. According to the composition formed by compatibility of the honey extract, the fig extract and the olive leaf extract, all the components have a synergistic effect, water and oil of the skin are effectively balanced, cutin is mildly peeled off, and the skin is smoothed and fined. Meanwhile, the composition can enhance a skin barrier, promote active matter absorption and repair sensitive skin, and the skin can be moisturized and bright after the composition is used for a long time.

The invention discloses an infant soothing skin cream suitable for sensitive skin and a preparation method of the infant soothing skin cream. The skin cream comprises the following components in parts by weight: 15-25 parts of an olive leaf extract, 15-25 parts of a radix ophiopogonis root extract, 10-18 parts of a purple coneflower extract, 10-16 parts of a honeysuckle flower extract, 3-7 parts of a purslane extract, 5-9 parts of a dendrobium nobile stem extract, 5-11 parts of trehalose, 12-20 parts of skin moistening grease, 8-16 parts of an emulsifier, 2-6 parts of a preservative, 2-6 parts of a pH regulator and 22-38 parts of deionized water. The invention relates to the technical field of infant skin cream, and particularly provides infant soothing skin cream suitable for sensitive skin, which is mild and non-irritant, can soothe and protect the skin of infants and a preparation method of the infant soothing skin cream.

The invention discloses a preparation method of an olive leaf extract. The preparation method comprises the following steps of: putting dried olive leaves into a polar solvent for extracting; recovering the solvent from an extracting solution, adding water and auxiliary materials, mixing uniformly, standing, filtering and combining filtrates; adsorbing a filtrate with macroporous resin, desorbingwith an ethanol-water mixed solution, and collecting a desorption solution; and recovering the solvent from the desorption solution, and drying to obtain the olive leaf extract. The method for preparing the olive leaf extract by adding auxiliary materials and purifying with the macroporous resin has the advantages of simple process, low cost and high content of oleuropein in the obtained olive leaf extract, and is suitable for large-scale production.

The invention discloses a plant composition with the effects of removing redness, resisting inflammation and relieving, and application. The composition comprises the following components: a, a bloodvessel repairing combination; and b. an olive leaf extract; the blood vessel repairing combination comprises a ruscus aculeatus root extract and escin.

The invention discloses a method for preparing hydroxytyrosol by combining enzymatic catalysis and high-temperature hydrolysis. The method comprises the following steps of performing enzymatic hydrolysis on oleuropein by cellulose which is rich in beta-glucosaccharase, wherein the using amount of cellulose is 10 to 60FPU / g of oleuropein; and directly controlling temperature to 80 to 100 DEG C without processing to continuously hydrolyze for 24 hours or more, and obtaining hydroxytyrosol solution, wherein the degradation rate of the obtained oleuropein is 95 percent or more, and the yield of the hydroxytyrosol is 80 percent or more. The hydroxytyrosol is prepared from an olive leaf extract by the method of combining enzymatic catalysis and high-temperature hydrolysis, reaction is performed through mild enzymatic catalysis, the using amount of enzyme is relatively small, cost is saved, the degradation rate of the obtained oleuropein is 95 percent or more, the yield of the hydroxytyrosol is 80 to 90 percent, and particularly the yield of the hydroxytyrosol is obviously improved, so that a foundation is laid for industrial production.

The invention discloses an olea europaea leaf extractive feed additive and application thereof. The olea europaea leaf extractive feed additive is prepared by the method comprising the following steps: preparing olea europaea leaves which are naturally dried in the shade as the raw materials; preparing an ethyl alcohol-water green organic mixing system with certain concentration as an extracting solvent; quickly extracting under a room temperature with ultrasonic assistance; filtering and drying to obtain olea europaea leaf extractive rich in active ingredients. The olea europaea leaf extractive prepared by the method is used as the feed additive and capable of promoting animal growth, improving the resistance to oxidative stress as well as improving immunity; the olea europaea leaf extractive feed additive is applicable to the field of nonreactive animal feed additives.

The present invention discloses hair care shampoo and a preparation method thereof. The hair care shampoo comprises the following components in parts by weight: 15-30 parts of sodium laureth sulfate,10-25 parts of sodium lauroamphoacetate, 2-8 parts of cocamidopropyl betaine, 1-5 parts of coconut oil diethanolamide, 1-3 parts of EDTA disodium, 2-4 parts of piroctone ethanolamide, 0.5-3 parts of nut seed oil, 1-3 parts of sodium chloride, 0.5-2 parts of sodium benzoate, 0.5-1 part of citric acid, 0.2-0.5 part of methylisothiazolinone, 0.5-1 part of wheat protein, 1-3 parts of an aloe vera leafextract, 1-2 parts of an olive leaf extract, 0.1-1 part of essence and 30-65 parts of water. The shampoo is mild in property, free of silicone oil, alcohol, pigment and nipagin ester preservatives, fine and smooth in foams, easy to wash, moderate in acidity and alkalinity, and capable of mildly cleaning scalp and hair, and at the same time protects the scalp health and enables the hair to be smooth and glossy.