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50results about How to "Prevent overproduction" patented technology

Compositions and methods for treatment of neurological disorders and neurodegenerative diseases

It has been discovered that the stimulation of beta-adrenergic receptors, which activate cAMP formation, give rise to increased APP and GFAP synthesis in astrocytes. Hence, the in vitro or in vivo exposure of neuronal cells to certain compositions comprising beta-adrenergic receptor ligands or agonists, including, e.g., norepinephrine, isoproterenol and the like, increases APP mRNA transcription and consequent APP overproduction. These increases are blocked by beta-adrenergic receptor antagonists, such as propranolol. The in vitro or in vivo treatment of these cells with 8Br-cAMP, prostaglandin E2 (PG E2), forskolin, and nicotine ditartrate also increased APP synthesis, including an increase in mRNA and holoprotein levels, as well as an increase in the expression of glial fibrillary acidic protein (GFAP). Compositions and methods are disclosed of regulating APP overexpression and mediating reactive astrogliosis through cAMP signaling or the activation of beta-adrenergic receptors. It has further been found that the increase in APP synthesis caused by 8Br-cAMP, PG E2, or forskolin is inhibited by immunosuppressants, immunophilin ligands, or anti-inflammatory agents, such as cyclosporin A, and FK-506 (tacrolimus), as well as ion-channel modulators, including ion chelating agents such as EGTA, or calcium / calmodulin kinase inhibitors, such as KN93. The present invention has broad implications in the alleviation, treatment, or prevention of neurological disorders and neurodegenerative diseases, including Alzheimer's Disease.
Owner:MASSACHUSETTS INST OF TECH

Device for rapidly responding to required ammonia amount changes in urea-hydrolysis ammonia preparation and implementation method of device

InactiveCN104556146APrevent overproductionAvoid the problem of slow response speed of hydrolysis ammonia productionSimultaneous control of multiple variablesAmmonia preparation/separationControl valvesHydrolysis
The invention discloses a device for rapidly responding to required ammonia amount changes in urea-hydrolysis ammonia preparation and an implementation method of the device, and mainly aims to solve the problem of low response speed in urea-hydrolysis ammonia preparation in the prior art. The device comprises a hydrolyzer, an ammonia gas flow control valve, a urine flow control valve, a urine input pipe, an ammonia gas output pipe, a signal analysis display alarming controller, a first signal converter and a second signal converter, wherein one end of the urine input pipe and one end of the ammonia gas output pipe are both communicated with the hydrolyzer; a signal output end of the signal analysis display alarming controller is connected with a signal input end of the first signal converter and the signal input end of the second signal converter respectively by signal wires; the signal output end of the first signal converter is connected with the ammonia gas flow control valve; the signal output end of the second signal converter is connected with the urine flow control valve. According to the scheme, the device disclosed by the invention has the advantage of realizing the aim of randomly controlling the yield of ammonia gas according to the amount of required ammonia and achieving high response speed in the urea-hydrolysis ammonia preparation.
Owner:成都天化化工工程技术有限公司

Novel high-speed blender

PendingCN107773071AIncrease powerMeet the needs of breaking the wallKitchen equipmentBall bearingDrive shaft
The invention discloses a novel wall breaking machine, which comprises a motor and a plastic cup. The motor is installed in a base, an upper cover is arranged on the upper side of the motor, and a touch screen switch is arranged on the front side of the upper cover. The touch screen switch controls the motor, and the motor is connected to Mushroom head sensor, the mushroom head sensor is installed in the center of the coaster, and the coaster is installed on the upper cover; the bottom of the plastic cup is provided with a fixed plate, the middle of the fixed plate is installed with a knife set, the center of the knife set is equipped with a drive shaft, the knife set A deep groove ball bearing is arranged on the lower side of the bottom of the drive shaft, and the transmission shaft passes through the deep groove ball bearing and is fixedly connected with the deep groove ball bearing. The mushroom head sensor is inserted into the bottom of the transmission shaft; the plastic cup is buckled on the coaster. The power of the motor is 30KW. The capacity of the plastic cup is 1.2L. The invention has greater power and can meet the wall-breaking needs of most foods; the use of small-capacity plastic cups avoids waste; effectively solves the problem that the traditional wall-breaking machine cannot be stuck, and has high transmission efficiency.
Owner:陈方

Fast moving consumer goods fleeing monitoring method and device based on identification analysis and medium

The invention discloses a fast moving consumer goods fleeing monitoring method and device based on identification analysis and a medium, belongs to the technical field of data processing methods specially suitable for business, and is used for solving the technical problems that an existing monitoring method is relatively tedious, large in workload and low in distinguishing efficiency. Comprising the following steps: allocating an identification prefix for an accessed enterprise and determining a two-dimensional identification code of each fast moving consumer goods; registering the business data of the business system and the two-dimensional identification code to an enterprise node of an identification analysis system; splicing the related data corresponding to the fast moving consumer goods, and constructing a knowledge graph of the fast moving consumer goods according to the basic information obtained by splicing and the two-dimensional identification code; scanning the two-dimensional identification code of the fast moving consumer goods to obtain user registration information, and obtaining basic information of the fast moving consumer goods from the knowledge graph; and submitting actual sales information of the fast moving consumer goods when it is determined that the fast moving consumer goods have a channel conflict behavior according to the sales information in the basic information and the fast moving consumer goods purchase address in the user registration information, so that an enterprise side and a consumption side can perform channel conflict monitoring.
Owner:浪潮工业互联网股份有限公司

A distributing system and distributing process of imitation natural stone ceramic tiles

A natural stone imitating ceramic tile material distributing system comprises a material distributing device, a material fixing box, an ejection device and a movable cutting device. The material fixing box is a material box with a left surface plate and a right surface plate which can be demounted and mounted. The width of the left surface plate and the width of the right surface plate are consistent with the width of an inner containing cavity of the material fixing box, and the left surface plate and the right surface plate are clamped to the left side and the right side of the material fixing box correspondingly. The left surface plate can slide in the material fixing box left and right. The ejection device is mounted on the left outer side of the material fixing box. The movable cutting device is arranged on the right outer side of the material fixing box. The natural stone imitating ceramic tile material distributing system is used for volume production and is high in production efficiency, and grain arranged by the system is finer, smoother and more vivid. In addition, the invention provides a material distributing procedure of a natural stone imitating green tile manufactured through the natural stone imitating ceramic tile material distributing system. The procedure is simple, and the natural stone imitating grain of the green tile is richer in effect and finer.
Owner:FOSHAN DONGPENG CERAMIC +2

Quantitative separation device for iron tailing sand raw materials

The invention discloses a quantitative separation device for iron tailing sand raw materials. The quantitative separation device comprises a shell, a separation cavity, a first motor, a driving roller, a first connecting roller, a screening belt, a second connecting roller, a linkage roller, a movable seat, a shell, a first spring, an end cover, a brake cable, a third connecting roller, a connecting rope, a groove, a sliding block, a first sliding groove, an input funnel, a second spring, a first valve plate, a pulley, a connecting block, a second sliding groove, a guide groove and the like. The quantitative separation device has the advantages of being reasonable and simple in structure, low in production cost, convenient to install and complete in function; a stirring device is arranged,a rotating disc can be driven to rotate through a second motor, and the rotating disc rotates to drive a movable plate and a stirring rod to move left and right through a fixed shaft and a connectinggroove body to stir the raw materials, so that the screening efficiency is improved; and a pulley mechanism is composed of the pulley, the connecting rope and the like, so that the moving range of the first valve plate is enlarged, and the quantitative control range and the control sensitivity are guaranteed.
Owner:HEBEI INSTITUTE OF ARCHITECTURE AND CIVIL ENGINEERING
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