Atipamezole hydrochloride-containing calming and pain easing tablet for pets, and preparation method thereof

Abstract

The invention belongs to the technical fields of antiparasitic agents for animals, and preparation methods thereof, and concretely relates to an atipamezole hydrochloride-containing calming and pain easing tablet for pets, and a preparation method thereof. The above preparation comprises an atipamezole hydrochloride raw drug, an adhesive, a wetting agent, a disintegrating agent, a filler and a sweetener. The atipamezole hydrochloride-containing tablet is prepared through a wet process, and is an off-white tablet. The atipamezole hydrochloride-containing tablet has good stability and good palatability, and can be used as an oral preparation for animals.

Description

technical field [0001] The invention belongs to the technical field of veterinary sedative and analgesic drugs and preparation methods, and in particular relates to a preparation method of atipamezole hydrochloride tablets. technical background [0002] Atipamezole hydrochloride, chemical name: 4-(2-ethyl-2-indan) imidazole hydrochloride. Atipamezole hydrochloride competitively inhibits alpha 2 adrenergic receptors, is an effective alpha 2 adrenergic receptor blocking drug, and it selectively and competitively inhibits alpha 2 adrenergic receptors effectively. Its pharmacological effect is to reduce sedation, lower blood pressure, increase heart rate and respiratory rate, and reduce the analgesic effect of α2 adrenergic receptor blocker. It is mainly used in anesthesia recovery after surgery on animals. Atipamezole hydrochloride is also in the stage of clinical evaluation research as a hypoglycemic and antihypertensive drug. At the same time, the drug has certain curative ...

AI Technical Summary

Problems solved by technology

At present, atipamezole hydrochloride is less produced at home and abroad, and there is a certain demand abroad