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Calcium supplementing preparation with functions of improving bones and joints

A technology for bone joints and preparations, applied in the field of new calcium supplementation preparations, can solve problems such as single, difficult to effectively prevent and improve degenerative bone diseases, and achieve the effects of increasing bone hardness, repairing cartilage, and improving joint structure

Inactive Publication Date: 2010-04-21
洛阳新春都生物制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, there are many health foods and medicines on the market for calcium supplementation for middle-aged and elderly people, but most of them are single calcium supplementation or calcium supplementation and trace element supplementation products, which are difficult to effectively prevent and improve various degenerative bone diseases

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] Embodiment 1 A calcium supplement (glucosamine nutritional capsule) that can improve bone and joint function is made from the following raw materials:

[0032] Medicinal calcium carbonate 20kg, glucosamine hydrochloride 8.5kg, olive juice freeze-dried powder 4kg, casein phosphopeptide 3kg, bone collagen 2.5kg, microcrystalline cellulose 2kg, mix and pulverize the above raw materials and pass through 80 mesh sieve , filled capsules, each containing 0.4g. Oral, three times a day, two capsules each time.

[0033] The safety experiment of the above calcium preparations was conducted by the Safety Toxicology Test Center of West China School of Public Health, Sichuan University, and the results are as follows:

[0034] ① Acute oral toxicity test: The acute oral MTD of Glucosamine Nutrition Capsules on SD rats is greater than 15g / kg.bw, which is classified as non-toxic.

[0035] ②Genotoxicity test: The results of Ames test, mouse bone marrow polychromatic erythrocyte micronu...

Embodiment 2

[0037] Example 2 A calcium supplement that can improve bone and joint function, made of the following raw materials:

[0038] Calcium citrate 20kg, calcium carbonate 20kg, glucosamine monomer 10kg, casein phosphopeptide 1kg, bone collagen 2kg, lycopene 1kg and medicinal starch 2kg, each raw material is mixed and ground, passed through a 100-mesh sieve, and pressed into tablets , 0.4g per tablet.

Embodiment 3

[0039] Example 3 A calcium supplement that can improve bone and joint function, made of the following raw materials:

[0040] Calcium gluconate 20kg, N-acetyl-D-glucosamine 20kg, casein phosphopeptide 0.5kg, bone collagen 1kg, natural astaxanthin 0.5kg and microcrystalline cellulose 2.5kg were made into pills by conventional methods.

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Abstract

The invention relates to a novel calcium supplementing preparation with functions of improving bones and joints, which is prepared from the following raw materials in parts by weight: 10-42 parts of calcium source components, 5-25 parts of amino sugar components, 0.1-5 parts of casein phosphopeptide, 0.5-5 parts of bone collagen protein, 0-8 parts of oxidation resistant components for human bodies and 0-3 parts of filling agents. The novel calcium supplementing preparation not only can supplement a calcium source to increase the bone hardness, but also can supplement bone collagen protein to increase the bone toughness for preventing calcium loss; the casein phosphopeptide is added to promote the calcium absorption, thereby solving the problem of the calcium absorption in the calcium supplementing process; and simultaneously, the oxidation resistant components and the components for promoting osteoblast proliferation are added to enable the bone reconstruction process formed by bone formation and bone absorption to balance again, thus the supplemented calcium can be reserved and firmly deposited on the bones. The related components in the novel calcium supplementing preparation can restore cartilages, improve the joint structure and interdict the deterioration of osteoarthritis.

Description

technical field [0001] The invention belongs to the field of health food, and in particular relates to a novel calcium supplement preparation capable of improving bone and joint functions. Background technique [0002] Osteoporosis is a systemic bone disease characterized by decreased bone mass and degeneration of bone tissue microstructure, resulting in increased bone fragility and increased risk of fracture. With the prolongation of people's life expectancy and the gradual increase in the incidence of social aging, the incidence of osteoporosis has jumped to the seventh place among the common diseases in the world, and it has become the leading cause of bone pain, fracture, disability and death due to fracture in middle-aged and elderly people. One of the main reasons. my country has entered an aging society, with a population of 130 million over 60 years old. The prevalence rate of osteoporosis in the Han population over 60 years old is 12.5%, among which hip fractures a...

Claims

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Application Information

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IPC IPC(8): A23L1/304A23L1/305A23L33/16A23L33/17A23L33/18
Inventor 孙建勋曹臣香赵文娟杨莲仝卓亚
Owner 洛阳新春都生物制药有限公司
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