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Pharmaceutical composition and preparation method thereof

A composition and medicine technology, applied in the field of pharmaceutical compositions and their preparation, can solve the problems of few pharmaceutical compositions, and achieve the effects of less side effects, good curative effect, and low preparation cost

Inactive Publication Date: 2015-01-14
SICHUAN TIANSHOU PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] But so far, there are few pharmaceutical compositions made from Desmodium

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] Take 10Kg of desmodium (Desmodium big-leaf) into the extraction tank, add water and decoct three times (add 12Kg of water for the first time, add 100Kg of water for the second time, add 100Kg of water for the third time, cook for 1 hour each time), and use a 100-mesh sieve filter.

[0029] The filtrate is sent to a three-effect energy-saving concentrator to be concentrated into a clear paste with a relative density of 1.22 (measured at 80-90°C), the concentration temperature is 50-90°C, and the vacuum degree is -0.01-0.06Mpa.

[0030] The clear paste is sieved through a 200-mesh sieve and sent to a spray drying granulator for spray drying at a drying temperature of 85-95°C and a drying time of 1.5 hours.

[0031] After drying, pulverize with a pulverizer, the mesh number of the pulverizer is 60 mesh, to obtain 1.85Kg of dry cream powder. Take samples for inspection.

[0032] The prepared dry cream powder and magnesium stearate (0.5% by weight of the dry cream powder) ...

Embodiment 2

[0035] The pharmaceutical composition prepared in Example 1 was subjected to a clinical curative effect experiment, and the clinical curative effect results of 300 cases were as follows: the cure rate was 23.3%, the effective rate was 43.3%, and the effective rate was 23.3%.

Embodiment 3

[0037] The pharmaceutical composition prepared in Example 1 was subjected to a cholelithiasis expulsion test, and it was found that it could prevent the precipitation of bile pigment components in bile and have a preventive effect on cholelithiasis.

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PUM

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Abstract

The invention discloses a pharmaceutical composition and a preparation method thereof. The pharmaceutical composition comprises a phenoloid, sterol, a flavonoid, amino acid, tannin, volatile oil, choline, sylvite, a glucoside compound and a lactone compound. The flavonoid comprises quercetin and kaempferide. Compared with the existing drug, the pharmaceutical composition is convenient for carrying, is a pure traditional Chinese medicine preparation, and has small side effects and taking safety.

Description

technical field [0001] The invention relates to a pharmaceutical composition and a preparation method thereof. Background technique [0002] Money grass, the name of traditional Chinese medicine. Harvested in summer and autumn. Remove impurities, dry in the sun, and cut into sections for raw use. [0003] But so far, there are few pharmaceutical compositions prepared from Desmodium. Contents of the invention [0004] One of the objectives of the present invention is to provide a pharmaceutical composition, which is convenient to carry, is a pure traditional Chinese medicine preparation, has few side effects and is safe to take. [0005] The technical solution is: a pharmaceutical composition comprising the following ingredients: [0006] Phenolic compounds, sterols, flavonoids, amino acids, tannins, volatile oils, choline, potassium salts, glycosides and lactones; the flavonoids include quercetin and kaempferol. [0007] Preferably, the weight sum of quercetin and ka...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/53A61P17/02A61P29/00A61P1/16A61P13/00
CPCA61K36/53A61K9/4858A61K31/352A61K45/06A61K2236/331A61K2236/39A61K2236/51
Inventor 淦吉银尹德明
Owner SICHUAN TIANSHOU PHARMA
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