Traditional Chinese medicine gastrointestinal developing agent for B ultrasound and preparation method thereof

A technology of contrast agent and traditional Chinese medicine, used in echo/ultrasonic imaging agents, etc., can solve the problems of strong gastric acid reaction, inability to use, no therapeutic effect, etc., and achieve the effects of simple preparation process, short inspection time, and no allergic reaction.

Inactive Publication Date: 2015-01-28
薛燕
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, for B-ultrasound gastrointestinal imaging aids, the prior art has recorded an imaging aid prepared by mixing 80% of octopus fine powder and 20% of bletilla striata 100-mesh fine powder, which has astringent and acid-stopping effects on gastrointestinal diseases , but the disadvantage is that the strong echo light spot produced by the patient after taking the contrast agent is insufficient, the reflection effect is not good, and the layer of the stomach wall is not displayed clearly; after the patient takes the contrast agent, the gastric acid reaction is strong, and there is pain and discomfort. It is beneficial for contrast-enhanced ultrasound of the gastrointestinal tract, and this contrast agent cannot be used for patients with gastric bleeding
The prescription uses bitter barrels, which taste extremely bitter, so sucrose is used to improve the taste, and sucrose easily produces bubbles when it enters the gastric juice, which affects the imaging effect. In addition, the product of this invention has no therapeutic effect

Method used

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Examples

Experimental program
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Effect test

preparation example Construction

[0043] The present invention further provides a method for preparing the above-mentioned traditional Chinese medicine gastrointestinal contrast aid for B-ultrasound, the dosage form of the traditional Chinese medicine contrast aid is granule, which comprises the following steps:

[0044] Step 1: Mix the raw medicinal materials according to the stated ratio, add ethanol with an alcohol concentration of 80% to 90% that is 3 to 5 times that of the mixture, heat to boiling and reflux for 2 to 4 hours, filter, and use percolation to remove Slowly percolate at a speed of 1-2ml per minute, collect the percolation liquid, then concentrate under reduced pressure at a vacuum of 0.06-0.09Mpa to a paste with a relative density of 1.00-1.10 at 50-60°C, spray dry, spray dry The air inlet temperature of the machine is 160-175°C, and the outlet air temperature is 80-85°C, and then crushed into powder to make dry cream powder;

[0045] Step 2: adding 0.3-0.5 times of sucrose powder and 0.2-0.4...

Embodiment 1

[0052] Embodiment 1: Granules

[0053] Take 320g white snail lion shell, 240g sea white stone, 340g phoenix tree, 110g water hyacinth fruit, 140g thorn rose, 180g Tangli branch and leaf, 120g multi-spike stone fruit, 70g green sheep ginseng, 180g cold berry root, 60g Agrimony, Horse tooth seven 70g, Tianshui antsweed 160g, golden thread bag 80g, black root 210g, snake white scorpion 120g, tangut green orchid 70g and yellow violet 60g.

[0054] Its preparation method comprises the following steps:

[0055] Step 1: Mix the raw medicinal materials according to the stated ratio, add ethanol with an alcohol concentration 3 times that of the mixture and 80% ethanol, heat to boiling and reflux for 2 hours, filter, and use percolation method at a rate of 2ml per minute to slowly Percolation, collect the percolation liquid, then concentrate under reduced pressure at 0.09Mpa to a paste with a relative density of 1.10 at 60°C, spray dry, the air inlet temperature of the spray dryer is 1...

Embodiment 2

[0057] Embodiment 2: syrup

[0058] Take 340g of white snail shell, 210g of sea white stone, 320g of phoenix seed, 140g of water hyacinth, 120g of thorn rose, 160g of Tangli branch and leaf, 140g of multi-spike stone fruit, 80g of green sheep ginseng, 160g of cold berry root, 70g of Agrimony, 80g horse tooth seven, 180g tianshui antweed, 60g gold thread bag, 230g black root, 140g snake white scorpion, 60g tangut green blue and 80g chrysanthemum violet.

[0059] Its preparation method comprises the following steps:

[0060] The first step is to press the fruit of chrysanthemum, green sheep ginseng, cold berry root, agrimony, horse tooth seven, Tianshui antweed, golden thread bag, black bark root, snake white scorpion, tangut green orchid and yellow violet Mix the ratios, add ethanol with an alcohol concentration 3 times that of the mixture and be 95% ethanol, heat and reflux for extraction 4 times, and extract for 3 hours each time, combine the extracts, and use a tube centrif...

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Abstract

The invention provides a traditional Chinese medicine gastrointestinal developing agent for B ultrasound and a preparation method thereof. The traditional Chinese medicine comprises the following raw herbal materials: spiral shell, balanophyllia sp, phoenix tree seeds, sterculia nobilis, dahurian rose flower, birchleaf pear branchlet and leaf, fruits of lithocarpus polystachyus, auricledleaf swallowwort root, buerger raspberry root, herba agrimoniae, fimbriate calanthe pseudobulb, autumn cudweed herb, tylophora yunnanensis, forestry greenstar root, ampelopsis brevipedunculata, Tangut dragonhead herb with root and flatstiped corydalis herb. The traditional Chinese medicine gastrointestinal developing agent has the benefits that the traditional Chinese medicine gastrointestinal developing additive for B ultrasound is safe, painless and free of allergic reaction during use, is short in examination time, high in imaging rate, convenient to use and low in cost, and is an ideal novel developing agent, a strong basis is provided for the clinical diagnosis, and the preparation process is simple and practical.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine engineering, in particular to a traditional Chinese medicine gastrointestinal imaging aid for B-ultrasound and a preparation method thereof. Background technique [0002] Ultrasound image diagnosis is one of the important diagnostic methods in medicine. Ultrasound has three major effects on matter: one is mechanical action, because the ultrasonic energy is huge, it often makes the material particles vibrate at high frequency mechanically, thus producing crushing, agglomeration, and stirring effects. The second is the thermal effect. When the ultrasonic wave acts on the substance, its energy is absorbed by the substance, thus increasing the temperature of the substance. The third is cavitation. When the ultrasonic wave acts on the liquid, the area with weak internal stress in the liquid (such as microscopic bubbles, etc.) becomes sparse due to the huge change in the sound pres...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K49/22
Inventor 薛燕李晓东
Owner 薛燕
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