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Nano Xiao'er Qifeng San and preparation method thereof

A kind of navel wind powder for children, nanotechnology, applied in the direction of medical formula, medical preparations containing active ingredients, plant raw materials, etc., can solve the problems of insufficient stability, strong purging effect, poor safety, etc., and achieve improvement Bioavailability, weakening of laxative effect, and effect of saving medicinal material resources

Active Publication Date: 2015-04-01
HAINAN HULUWA PHARMA GRP CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The disadvantages of the infant navel wind powder obtained by this preparation method are: low drug efficacy, high toxicity, too strong purging effect, and not mild enough for children; more importantly, the stability is not good enough during long-term storage , it is possible to produce soluble mercury or free mercury, which is not safe

Method used

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  • Nano Xiao'er Qifeng San and preparation method thereof
  • Nano Xiao'er Qifeng San and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] Scorpion 600g Pig Tooth Soap 1200g Rhubarb 1200g

[0038] Angelica 180g Naumous sand (burnt) 60g Croton cream 60g

[0039] Cinnabar 3300g Artificial Bezoar 30g

[0040] (1) The four medicinal materials of scorpion, pig tooth soap, angelica, and croton cream were nano-pulverized with a nano pulverizer, and the pulverization time was 1 hour, and the particle size was 200nm, and set aside.

[0041] (2) Remove the iron filings from the cinnabar, put it in a ball mill crushing tank, add water 5 times the weight of the medicinal material at the same time, and carry out wet pulverization of the cinnabar for 60 minutes under the condition of 320rpm to obtain a suspension, take it out, and put the suspension Transfer to a sand-type suction filter for suction filtration, then transfer to a centrifuge for dehydration for 30 minutes, take it out, put it on cotton cloth or absorbent paper, transfer it to a hot air circulation box and dry it at 40°C.

[0042] (3) Put the rhubarb in...

Embodiment 2

[0045] Scorpion 600g Pig Tooth Soap 1200g Rhubarb 1200g

[0046] Angelica 180g Naumous sand (burnt) 60g Croton cream 60g

[0047] Cinnabar 3300g Artificial Bezoar 30g

[0048] (1) The four flavors of scorpion, pig tooth soap, angelica, and croton cream were nano-pulverized with a nano-pulverizer, and the crushing time was 1 hour, and the particle size was 200nm, and they were set aside.

[0049] (2) Remove the iron filings from the cinnabar, put it in a ball mill crushing tank, add water 3 times the weight of the medicinal material at the same time, and carry out wet pulverization of the cinnabar under the condition of 320rpm to obtain a suspension, take it out, and mix the suspension Transfer to a sand-type suction filter for suction filtration, then transfer to a centrifuge for dehydration for 50 minutes, take it out, put it on cotton cloth or absorbent paper, and transfer it to a hot air circulation box to dry at 40°C.

[0050] (3) Put the rhubarb in a pressure cooker, ad...

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Abstract

The invention discloses nano Xiao'er Qifeng San and a preparation method thereof. The nano Xiao'er Qifeng San is prepared from 500-800 parts of scorpion, 1,000-1,500 parts of fructus gleditsiae, 1,000-1,500 parts of rhubarb, 150-200 parts of angelica sinensis, 50-100 parts of mix-fried sal ammoniac, 50-100 parts of defatted croton seed powder, 3,000-3,500 parts of cinnabar and 20-50 parts of calculus bovis factitious. According to the method, Xiao'er Qifeng San is prepared with the nano technology, the content of free mercury in cinnabar can be reduced through ball milling and grinding in water, toxicity of rhubarb cooked by yellow wine is small, the medicine efficacy is high, further, the quality is stable, and the bioavailability is high; and besides, the preparation method is simple, does not require any special equipment and is applicable to industrial production.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine preparations, in particular to a nanometer baby navel wind powder and a preparation method thereof. Background technique [0002] The whole prescription of Xiaoer Navel Wind San is composed of scorpion, pig tooth soap, rhubarb, angelica, Naosha (burned), croton, cinnabar, and artificial bezoar. Has heat-clearing and wind-dispelling, suppresses convulsion and expectorant. It is used for newborn infants who are easily startled when sleeping or lying down caused by internal heat of fetal fire, restless crying, hot body and flushed face, cough with profuse phlegm, constipation, convulsions and convulsions. [0003] The Xiaoer Navel Wind Powder in the prior art is prepared by the following method: water flying or crushing cinnabar into fine powder; crushing scorpion, pig tooth soap, rhubarb, angelica and croton into fine powder; Fine, compound with the above-mentioned powder for grinding, ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/708A61K9/14A61P25/20A61P25/08A61P29/00A61P11/14A61P11/10A61P1/10A61K35/413A61K35/646A61K33/28A61K33/20
CPCA61K9/14A61K33/20A61K33/28A61K35/413A61K35/646A61K36/232A61K36/47A61K36/483A61K36/708A61K2300/00
Inventor 刘景萍刘全国陈克领林文君
Owner HAINAN HULUWA PHARMA GRP CO LTD
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