Synthesis method of pyraclostrobin

A technology of pyraclostrobin and a synthetic method, which is applied in the field of synthesis of pyraclostrobin, can solve the problems of few by-products, difficult separation, difficult purification of final products, etc., and achieve the effect of low production cost

Inactive Publication Date: 2015-05-06
ANHUI COSTAR BIOCHEM CO LTD
View PDF4 Cites 39 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The first condensation method is to prepare pyraclostrobin through the eight-step reaction of p-chlorophenylhydrazine hydrochloride synthesis, cyclization, oxidation, bromination, etherification, reduction, esterification and methylation. The yield is high, and the conditions are relatively mild; the post-condensation method is to prepare pyraclofenac by synthesis, cyclization, oxidation, reduction, esterification, methylation, bromination and conden

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Synthesis method of pyraclostrobin
  • Synthesis method of pyraclostrobin
  • Synthesis method of pyraclostrobin

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029]

Embodiment 2

[0031]

[0032]

Embodiment 3

[0034]

[0035]

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention aims at providing a synthesis method of pyraclostrobin. The method comprises the following steps: with chloroaniline and ortho-nitrotoluene as raw materials, synthesizing, cyclizing, oxidizing, bromizing, etherifying, reducing, esterifying and methylating chlorophenylhydrazine hydrochloride to prepare the pyraclostrobin. The purity of the pyraclostrobin synthesized through the method disclosed by the invention is 98.0% and more, the yield reaches 48%. And the process is low in cost, simple to operate and easy for industrial production.

Description

technical field [0001] The invention relates to the field of pesticide fungicides, in particular to a method for synthesizing pyraclostrobin. Background technique [0002] Pyraclostrobin, also known as pyraclostrobin, is a broad-spectrum fungicide of methyl methoxyacrylate with a pyrazole structure discovered by BASF in 1993, with molecular formula C 19 h 18 ClN 3 o 4 , whose structure is [0003] [0004] Pyraclostrobin has patent rights in the United States, Europe and other countries, and has also applied for a patent in my country, but its synthesis technology has not yet been disclosed. At present, the synthetic route of pyraclostrobin at home and abroad can be divided into the following two types: the first condensation method and the post-condensation method, both of which are based on o-nitrotoluene and p-chloroaniline as starting materials. The first condensation method is to prepare pyraclostrobin through the eight-step reaction of p-chlorophenylhydrazine h...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): C07D231/22
CPCC07D231/22
Inventor 谷顺明刘敏王红伟王晓亭
Owner ANHUI COSTAR BIOCHEM CO LTD
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products