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Traditional Chinese medicine preparation for treating xerophthalmia

A traditional Chinese medicine preparation and technology for dry eye syndrome, applied in the field of traditional Chinese medicine preparations for the treatment of dry eye syndrome, can solve problems such as slowing down evaporation or loss, inconvenient storage, and epiphora, and achieves the effect of simple medication and less dosage

Inactive Publication Date: 2015-05-20
苏风军
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There are various causes of dry eye, and the pathogenesis has not been fully clarified. The treatment of dry eye is still in the stage of symptomatic treatment, and it is difficult to cure it.
At present, the most commonly used method to treat dry eye is local application of artificial tears to moisten the cornea and conjunctiva, increase the viscosity of tears, slow down its evaporation or drainage, etc., but the improvement effect on dry eye symptoms is very limited
Moreover, at present, many artificial tears contain preservatives. Although the content is very low, long-term use can lead to iatrogenic aggravation of ocular surface diseases; even artificial tears without preservatives also have disadvantages. Sexuality declines as patients have to carry it with them for 24-hour use
Moreover, many artificial tears need to be refrigerated, which is inconvenient to store
Although the lacrimal canalicular embolization is less painful and easy to operate, the disadvantages are that the occluder may cause irritation, the occluder is lost or slipped into the lacrimal duct, epiphora occurs after the punctum is closed, and irreversible damage after permanent occlusion
Submandibular gland transplantation has become a relatively mature surgical method for the treatment of dry eye in ophthalmology in recent years. Difficult to popularize
However, the current research on the treatment of dry eye in traditional Chinese medicine has the following problems: (1) The current research on the treatment of dry eye in traditional Chinese medicine is still mainly focused on summarizing the laws of syndrome differentiation and observing the curative effect of traditional Chinese medicine, lacking in theory, method, prescription, and medicine. systematic research
(2) Lack of unified curative effect evaluation standards, especially the curative effect judgment standards of traditional Chinese medicine itself, making it difficult to objectively evaluate curative effect
(3) At present, most clinical observations lack rigorous design, stay at the level of experience summarization, lack long-term follow-up observations with large samples, some clinical studies lack control groups, and observation indicators are mostly measured by subjective indicators such as improvement of clinical symptoms. Insufficient observation of long-term efficacy makes the research results lack strong convincing

Method used

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  • Traditional Chinese medicine preparation for treating xerophthalmia
  • Traditional Chinese medicine preparation for treating xerophthalmia
  • Traditional Chinese medicine preparation for treating xerophthalmia

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Example 1: Take 15g of Mimeng flower, 20g of dendrobium, 20g of medlar, 6g of chrysanthemum, 12g of scrophulariaceae, 12g of Ophiopogon japonicus, 20g of Schisandra chinensis, 12g of raw land, 15g of white peony, 15g of asparagus, 12g of dogwood, and 12g of fried yam.

[0033] Decoction in water, one dose per day, one month is a course of treatment. It is effective in treating dry eye syndrome.

Embodiment 2

[0034] Example 2: Take 10g of Mimeng flower, 15 of dendrobium, 15 of medlar, 3 of chrysanthemum, 10 of scrophulariaceae, 10g of Ophiopogon japonicus, 15-20g of Schisandra chinensis, 10-12g of raw land, 10-15g of white peony root, 10-15g of asparagus, Cornus officinalis 10-12g, fried yam 10-12g.

[0035] Decoction in water, one dose per day, one month is a course of treatment. It is effective in treating dry eye syndrome.

[0036] Clinical Trial Data

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PUM

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Abstract

The invention relates to a traditional Chinese medicine preparation for treating xerophthalmia. The traditional Chinese medicine preparation is prepared from the following ingredients by weight: 10-15g of pale butterflybush flower, 15-20g of stem of noble dendrobium, 15-20g of barbary wolfberry fruit, 3-6g of chrysanthemum, 10-12g of figwort root, 10-12g of dwarf lilyturf tuber, 15-20g of Chinese magnoliavine fruit, 10-12g of rehmannia root, 10-15g of white paeony root, 10-15g of cochinchnese asparagus root, 10-12g of common macrocarpium fruit and 10-12g of stir-fried rhizoma dioscoreae. A preparation method comprises the following steps: adding proper amount of water to soak the active pharmaceutical ingredients for half an hour, then decocting the active pharmaceutical ingredients with slow fire until 300ml of liquor is left, filtering out the liquor, then adding proper amount of water, decocting the active pharmaceutical ingredients with slow fire until 200ml of liquor is left, filtering out the liquor, mixing the two liquors, halving the liquor mixture and taking the halved liquor mixture once in the morning and once in the evening. The traditional Chinese medicine preparation is simple and convenient to take, is small in dosage and does not have obvious side effects.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, in particular to a traditional Chinese medicine preparation made of pure traditional Chinese medicines for treating dry eye. Background technique [0002] Dry eye is a chronic eye disease in which the redness and swelling of the eyes are not obvious, but the eyes are dry and uncomfortable. It belongs to the category of "white astringency syndrome" and "shenshui will dry up" in traditional Chinese medicine. "Scrutiny of Yao Han" refers to white astringency syndrome: "the disease is not swollen or red, but astringent and painful. It is the hidden fire of qi, the spleen and lung collaterals Damp and hot, often suffer from this in autumn." "On the Origin and Symptoms of Various Diseases·Mushu Hou" says: "When the fluid is exhausted, the eyes will be astringent." The five internal organs are fully harmonized, metaplasia is active, and the body fluid turns into divine water in the eyes, mo...

Claims

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Application Information

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IPC IPC(8): A61K36/8984A61P27/02
Inventor 不公告发明人
Owner 苏风军
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