Traditional Chinese medicine composition for treating senile dementia
A composition and technology of traditional Chinese medicine, applied in the field of traditional Chinese medicine composition for the treatment of senile dementia, can solve problems such as decreased judgment ability, difficulty in naming, and apathy
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Embodiment 1
[0021] Embodiment 1: medicine preparation
[0022] Raw materials: 10 grams of Salvia miltiorrhiza, 10 grams of angelica, 6 grams of ginseng, 6 grams of Shichangpu, 6 grams of Yizhiren, 6 grams of Chuanxiong, 10 grams of Astragalus, and 6 grams of Polygala.
[0023] Preparation steps:
[0024] 1) Weighing the bulk drug in said weight portion;
[0025] 2) Add 10 times the amount of 80% ethanol by weight, heat and reflux for extraction, repeat the above operation and extract once more, each time for 2 hours, combine the extracts, and filter to obtain the filtrate;
[0026] 3) Ethanol is recovered from the filtrate and concentrated to a thick paste;
[0027] 4) Dry the thick paste and crush it into fine powder;
[0028] 5) Divide the fine powder into capsules.
experiment example
[0029] Experimental example: drug efficacy test
[0030] Animals: 80 SPF grade KM mice, 18-22g, half male and half male.
[0031] Medicine: the traditional Chinese medicine composition of the present invention, the thick ointment fine powder of embodiment 1 is added distilled water to prepare suspension.
[0032] Control drug: piracetam tablets, made into fine powder, added with distilled water to make suspension.
[0033] experimental method:
[0034] The mice were randomly divided into 4 groups according to body weight: a control group, a model group, a Chinese medicine composition group of the present invention, and a piracetam group, with 20 mice in each group. Except for the control group intraperitoneally injected with the same amount of normal saline and gavage with the same amount of distilled water, the other groups were intraperitoneally injected with D-galactose 60mg / (kg. preparation), once a day for 60 days in a row. The Chinese medicine composition of the pres...
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