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A traditional Chinese medicine composition for alleviating chemical liver injury, its preparation method and traditional Chinese medicine preparation
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A technology of chemical liver injury and traditional Chinese medicine preparations, applied in the direction of drug combinations, pharmaceutical formulas, medical preparations containing active ingredients, etc., can solve the problems of aggravating liver oxidative damage and achieve the effect of protecting the liver
Active Publication Date: 2018-03-23
JIANGSU KANION PHARMA CO LTD
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Alcohol has no significant effect on the activity of superoxide dismutase (SOD) in the liver and mitochondria, but it can inhibit the activity of glutathione peroxidase (GPX1) in the liver and mitochondria, resulting in the depletion of reduced glutathione (GSH), oxidative damage to the liver
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preparation example Construction
[0032] The preparation method of described turmeric extract is more preferably:
[0033] Take turmeric and grind it, extract 2 times with 10 times the amount of 50% ethanol, each time for 2.5 hours, the extraction temperature is 60°C, combine the extracts, filter, concentrate until the mass ratio of turmeric and dry paste is 10:1, and obtain turmeric extract thing.
[0034] According to pharmacological analysis: kudzu root clears heat and detoxifies, ganoderma lucidum enhances immunity, centella asiatica promotes blood circulation and removes blood stasis, rhodiola invigorates qi and invigorates the spleen, combined with turmeric to promote qi and break blood stasis, licorice harmonizes all medicines, together play a role in clearing damp heat, detoxifying Alcohol poisoning, soothes the liver and gallbladder, and has the effects of stagnation. Therefore, after the above-mentioned several substances are compounded and interact with each other, they have a good alleviating effe...
Embodiment 1
[0061] The preparation of embodiment 1 Chinese medicine composition
[0062] Mix 20 grams of kudzu root, 20 grams of ganoderma lucidum, 10 grams of centella asiatica, 10 grams of rhodiola rosea and 10 grams of licorice, add 700 grams of water, and extract once at 90 ° C for 0.6 hours; reduce pressure at 60 ° C Concentrate to a density of 1.0 g / ml, and spray dry to obtain the material; the inlet temperature of the hot air during the spray drying is 150°C, and the outlet temperature is 70°C.
[0063] The material is mixed with 1 gram of turmeric extract to obtain a traditional Chinese medicine composition for alleviating chemical liver damage.
Embodiment 2
[0064] The preparation of embodiment 2 Chinese medicine composition
[0065] Mix 60 grams of kudzu root, 60 grams of ganoderma lucidum, 50 grams of centella asiatica, 50 grams of rhodiola rosea and 30 grams of licorice, add 2500 grams of water, extract once at 95°C for 1.5 hours; reduce pressure at 60°C Concentrate to a density of 1.2g / ml, and spray dry to obtain the material; the hot air inlet temperature during the spray drying is 160°C, and the outlet temperature is 80°C.
[0066] The material is mixed with 10 grams of turmeric extract to obtain a traditional Chinese medicine composition for alleviating chemical liver damage.
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Abstract
The invention provides a traditional Chinese medicine composition for relieving chemical liver damage, which is made of the following components in parts by weight: 2-6 parts by weight of Pueraria root, 2-6 parts by weight of Ganoderma lucidum, 1-5 parts by weight of Centella asiatica, Hongjing Tian 1-5 parts by weight, licorice 1-3 parts by weight, turmeric extract 0.1-1 parts by weight. Among them, kudzu root clears heat and detoxifies, Ganoderma lucidum enhances immunity, Centella asiatica promotes blood circulation and removes blood stasis, Rhodiola nourishes qi and invigorates the spleen, together with turmeric to promote qi and break blood stasis, licorice harmonizes all medicines, together play a role in clearing dampness and heat, detoxifying alcohol, soothing liver and gallbladder, The effect of stagnation. Therefore, after the above-mentioned several substances are compounded and interact with each other, they have a good alleviating effect on chemical liver injury, thereby protecting the liver. The invention also provides a preparation method of the composition, a traditional Chinese medicine preparation made of the composition and auxiliary materials and an application of the composition in preparing a health care product with a protective effect on chemically damaged liver.
Description
technical field [0001] The invention relates to the field of health care products, in particular to a traditional Chinese medicine composition for alleviating chemical liver damage, a preparation method thereof and a traditional Chinese medicine preparation. Background technique [0002] Liver injury is a pathological change in the liver caused by factors such as viruses, drugs, poisons, alcohol, and hypoxia. The mechanism of liver injury is complex, which can be divided into chemical and immune. The chemical mechanism is mainly due to plasma membrane damage, free radical damage, mitochondrial dysfunction, metabolic disorder and other factors leading to liver function damage. Chemical liver injury can be caused by the effects of alcohol, chemical poisons in the environment, and certain drugs. [0003] At present, most of the clinical chemical liver injury is caused by alcohol, and the resulting alcoholic liver disease has also become the focus of social attention, includin...
Claims
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Application Information
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