An aerosol precursor containing medicinal effective components in a snake bile-tendrilleaf fritillary bulb soft capsule and a method of dispersing the medicinal effective components into nanometer fog drops

A technology of snake gallbladder and medicinal ingredients, which is applied in the field of aerosol precursors, can solve the problems of harsh airtightness requirements of propellant storage tanks, poor drug atomization effect, and high cost of propellants, etc. Medicinal value, good suction feeling, effect of shortening the action time

CN104758564AInactive Publication Date: 2015-07-08CHINA TOBACCO YUNNAN IND
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Publication Date
2015-07-08
Estimated Expiration
Not applicable · inactive patent
Patent Text Reader

Abstract

The invention relates to an aerosol precursor containing medicinal effective components in a snake bile-tendrilleaf fritillary bulb soft capsule. The aerosol precursor comprises glycerol, propanediol, 1,3-butanediol, a fragrance compound and a snake bile-tendrilleaf fritillary bulb soft capsule extract in a mass ratio of (40-45):(20-25):(0-10):(0-10):(1-10). The invention also relates to a method of dispersing the medicinal effective components in the snake bile-tendrilleaf fritillary bulb soft capsule into nanometer fog drops, and relates to an aerosol containing the nanometer fog drops. The aerosol precursor comprises the medicinal effective components in the snake bile-tendrilleaf fritillary bulb soft capsule. The nanometer fog drops can be obtained by adding the aerosol precursor into an electronic cigarette smoking set containing an electric heating device and heating, thus benefiting absorption of the medicinal effective components for a human body.
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Description

Technical field

[0001] The present invention relates to an aerosol precursor, in particular to an aerosol precursor containing medicinal ingredients of Shedan Chuanbei soft capsule and a method for dispersing it into nanometer droplets. Background technique

[0002] The main ingredients of Snake Dan Chuanbei Soft Capsules are snake bile and Chuanbei mother. It is a soft capsule, the content is a light yellow oily suspension; it tastes slightly bitter and has the effects of clearing the lungs, relieving cough, and eliminating phlegm. Usually, the administration method of Shedan Chuanbei soft capsule is oral administration. On the one hand, the drug effect is slow; on the one hand, it will cause the irritation of the drug to the stomach; on the other hand, the first pass effect of the liver will be Decrease drug utilization.

[0003] Aerosol generally refers to a preparation that can produce mist droplets under heat or pressure. In the field of medical pharmacy, aerosols refer to ...

Examples

Embodiment 1

[0030] An aerosol precursor containing active ingredients of Snake Dan Chuanbei soft capsules, which contains glycerol, propylene glycol, 1,3-butanediol, flavor substances and Snake Dan Chuanbei soft capsule extract, and their mass ratio is Glycerol: Propylene Glycol: Snake Dan Chuanbei Soft Capsule Extract=40:20:1.

[0031] Wherein, the snake gall chuanbei soft capsule extract is obtained by a method including the following steps:

[0032] (1) Impurity removal: Dissolve the contents of the Snake Dan Chuanbei soft capsule in edible ethanol, filter to remove insoluble impurities, and obtain the ethanol solution of the Snake Dan Chuanbei soft capsule;

[0033] (2) Decolorization: Pass the ethanol solution of the Shedan Chuanbei soft capsule obtained in step (1) through the first macroporous resin chromatographic column, and elute it with an ethanol-water solution with a concentration of 40% by volume to remove the pigment components, and The solvent is removed by molecular distillatio...