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Preparation process and quality control method of cassia twig poria cocos preparation

A technology of Guizhi Fuling Pills and Poria cocos, which is applied in measuring devices, medical formulas, medical preparations containing active ingredients, etc., can solve the problems of low degree of mechanization, long disintegration time limit, and long process

Inactive Publication Date: 2015-08-05
陈世忠
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Due to the general manufacturing process adopted, there are problems such as low degree of mechanization, high labor intensity, long process, difficult control of hygienic indicators, long disintegration time limit, difficult control of pellet weight difference, and many tailings, which seriously affect to the clinical application of the preparation

Method used

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  • Preparation process and quality control method of cassia twig poria cocos preparation
  • Preparation process and quality control method of cassia twig poria cocos preparation
  • Preparation process and quality control method of cassia twig poria cocos preparation

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] Embodiment 1. The preparation of Guizhi Fuling pill

[0034] 1. Prescription: Guizhi 60g, Poria cocos 60g, peony 60g, Moutan bark 60g, peach kernel 60g

[0035] 2. Preparation method: the above five flavors, cassia twig, poria cocos and peony cortex are crushed into fine powder, sieved, mixed evenly, and set aside; peony and peach kernels are mixed and ground into very fine powder, sieved, set aside; mix the above powders evenly , add 5% starch slurry for wet granulation, dry in an oven at 50°C, granulate, add 10% lactose and 0.3% magnesium stearate by total weight, mix evenly, press into 1000 pills, coat with film, and get ready.

[0036] 3. Properties: This product is a pink film-coated pill, the core of which is light brown and white, with a specific gas and sweet taste.

[0037] 4. Specification: 0.3g / pill.

[0038] 5. Three batches of samples were prepared according to the above production process. The production process and physical and chemical properties are a...

Embodiment 2

[0042] Embodiment 2. Preparation of Guizhi Fuling Pills

[0043] 1. Prescription: Guizhi 60g, Poria cocos 60g, peony 60g, Moutan bark 60g, peach kernel 60g

[0044] 2. Preparation method: the above five flavors, cinnamon twigs, poria cocos, and peony cortex are crushed into the finest powder, sieved, mixed, and set aside; peony and peach kernels are mixed and ground into the finest powder, sieved, set aside; mix the above powders evenly , add 5% dextrin solution for wet granulation, dry in an oven at 50°C, granulate, add 10% sodium carboxymethyl starch and 0.3% magnesium stearate by total weight, mix evenly, press into 1000 pills, coat with film, Instantly.

[0045] 3. Properties: This product is a pink film-coated pill, the core of which is light brown and white, with a specific gas and sweet taste.

[0046] 4. Specification: 0.3g / pill.

[0047] 5. Three batches of samples were prepared according to the above production process. The production process and physical and chem...

Embodiment 3

[0052] Embodiment 3. Preparation of Guizhi Fuling Pills

[0053] 1. Prescription: Guizhi 60g, Poria cocos 60g, peony 60g, Moutan bark 60g, peach kernel 60g

[0054] 2. Preparation method: the above five flavors, cinnamon sticks, poria cocos, peony cortex, and peony are pulverized into superfine powders, sieved, mixed, and set aside; peach kernels are pulverized into fine powder, sieved, set aside; mix the above powders evenly, add 5 Wet granulation of % starch slurry, drying in an oven at 50°C, granulation, adding 12% sucrose and 0.5% magnesium stearate by total weight, mixing evenly, pressing into 1000 pellets, coating with film, to obtain.

[0055] 3. Properties: This product is a pink film-coated pill, the core of which is light brown and white, with a specific gas and sweet taste.

[0056] 4. Specification: 0.3g / pill.

[0057] 5. Three batches of samples were prepared according to the above production process. The production process and physical and chemical properties a...

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Abstract

The invention provides a preparation process and a quality control method of a cassia twig poria cocos preparation. The preparation method has the advantages of less production steps, short production period, high production mechanical degree, stable quality of the preparation, high content of effective components, rapid disintegration, high bioavailability, small dose oral administration, convenience in oral administration and the like. The invention also provides a quality control method of cinnamaldehyde, cinnamic acid, paeonol, paeoniflorin and amygdalin in a cassia twig poria cocos pill.

Description

technical field [0001] The invention relates to a preparation process and quality control method of cinnamon twig and poria cocos preparation. Background technique [0002] Guizhi Fuling Pills was first recorded in the famous prescription of "Synopsis of the Golden Chamber" written by Zhang Zhongjing in the Han Dynasty. And dysmenorrhea and amenorrhea caused by congestion, crux lumps, is a famous prescription for promoting blood circulation and removing blood stasis. Guizhi Fuling pills are composed of cinnamon twigs, poria cocos, peony, peach kernels and paeonol. Eliminate blood stasis, break disease accumulation, remove blood stasis and generate new energy; combined into a prescription, it can attack the toughness without hurting the body, and eliminate blood stasis without hurting the yin. In recent years, it has been widely used in the treatment of gynecological common diseases or frequently-occurring diseases such as gynecological uterine fibroids, ovarian cysts, endo...

Claims

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Application Information

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IPC IPC(8): A61K36/736A61P15/00A61P35/00A61P15/06A61P15/08G01N30/36
Inventor 陈世忠金洁
Owner 陈世忠
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