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A kind of suture suitable for intradermal and preparation method thereof

A technology of sutures and quality parts, which is applied in the field of medical sutures, can solve the problems of reducing friction, reducing tensile strength and elongation, and affecting the effect of sutures, so as to improve tensile strength and elongation and reduce friction Effect

Inactive Publication Date: 2017-08-25
SUZHOU JONATHAN NEW MATERIALS TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, while the existing intradermal sutures reduce friction, the tensile strength and elongation are also reduced, which affects the suture effect and is not enough to meet the requirements of clinical treatment.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] A suture thread suitable for intradermal use, consisting of the following components by mass: 45 parts of polypropylene, 17 parts of butanediol, 9 parts of glycerin, 5 parts of maleic anhydride, 2 parts of ammonium dihydrogen phosphate, polylactic acid 13 parts, 2 parts of polyglycolide, 4 parts of 2,6-tertiary butyl-4-methylphenol.

[0017] Preparation:

[0018] (1) According to the above mass parts, put polypropylene in a reaction kettle, melt it at 160°C, then add butanediol, glycerin, maleic anhydride, ammonium dihydrogen phosphate, polylactic acid, polyglycolide and 2, 6-tertiary butyl-4-methylphenol, sonicated for 10 minutes at 80°C to obtain a mixture;

[0019] (2) Send the mixture obtained in step (1) into a twin-screw extruder for granulation, cool, dry, and cut to obtain masterbatches. The temperature of the twin-screw extruder is 210°C, and the screw speed is 700r / min ;

[0020] (3) Heat the masterbatch obtained in step (2) to 120°C, pass through a spinner...

Embodiment 2

[0022] A suture thread suitable for intradermal use, consisting of the following components by mass: 63 parts of polypropylene, 29 parts of butanediol, 18 parts of glycerin, 21 parts of maleic anhydride, 11 parts of ammonium dihydrogen phosphate, polylactic acid 27 parts, polyglycolide 10 parts, 2,6-tertiary butyl-4-methylphenol 18 parts.

[0023] Preparation:

[0024] (1) According to the above mass parts, put polypropylene in the reaction kettle and melt it at 210°C, then add butanediol, glycerin, maleic anhydride, ammonium dihydrogen phosphate, polylactic acid, polyglycolide and 2, 6-tertiary butyl-4-methylphenol, sonicated at 100°C for 20 minutes to obtain a mixture;

[0025] (2) Send the mixture obtained in step (1) into a twin-screw extruder for granulation, cool, dry, and cut to obtain masterbatches. The temperature of the twin-screw extruder is 260°C, and the screw speed is 1000r / min ;

[0026] (3) Heat the masterbatch obtained in step (2) to 150°C, pass through a s...

Embodiment 3

[0028] A suture thread suitable for intradermal use, consisting of the following components by mass: 48 parts of polypropylene, 21 parts of butanediol, 11 parts of glycerin, 7 parts of maleic anhydride, 4 parts of ammonium dihydrogen phosphate, polylactic acid 15 parts, 4 parts of polyglycolide, 5 parts of 2,6-tertiary butyl-4-methylphenol.

[0029] Preparation:

[0030] (1) According to the above mass parts, put polypropylene in the reaction kettle, melt it at 170°C, then add butanediol, glycerin, maleic anhydride, ammonium dihydrogen phosphate, polylactic acid, polyglycolide and 2, 6-tertiary butyl-4-methylphenol, sonicated at 85°C for 12 minutes to obtain a mixture;

[0031] (2) Send the mixture obtained in step (1) into a twin-screw extruder for granulation, cool, dry, and cut to obtain masterbatches. The temperature of the twin-screw extruder is 220°C, and the screw speed is 800r / min ;

[0032] (3) Heat the master batch obtained in step (2) to 130°C, pass through a spi...

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Abstract

The invention discloses a suture suitable for intradermal and a preparation method thereof. The suture is composed of the following components in parts by mass: 45-63 parts of polypropylene, 17-29 parts of butanediol, and 9-18 parts of glycerin 5-21 parts of maleic anhydride, 2-11 parts of ammonium dihydrogen phosphate, 13-27 parts of polylactic acid, 2-10 parts of polyglycolide, 2,6-tertiary butyl-4-methylphenol 4 ‑18 servings. The suture thread prepared by the invention improves tensile strength and elongation, reduces frictional force, is suitable for intradermal suture, and can be widely used in clinical treatment.

Description

technical field [0001] The invention belongs to the field of medical sutures, and in particular relates to a suture suitable for intradermal use and a preparation method thereof. Background technique [0002] Surgical suture refers to the special thread used for ligation hemostasis, suture hemostasis and tissue suture in surgical operation or trauma treatment. It can generally be divided into two categories: absorbable thread and non-absorbable thread. According to the material and the degree of absorption, it is divided into: catgut, chemical synthetic thread (PGA), and pure natural collagen suture. [0003] The requirements for surgical sutures are as follows: 1. It can maintain sufficient strength during the wound healing process, and it should also be able to stretch to adapt to the wound edema, and retract to the original length as the wound retracts; 2. After the wound is healed, its It can also be degraded and absorbed by itself without leaving foreign matter; 3 does...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61L17/10A61L17/00A61L17/12
Inventor 吕少波李卓才李苏杨
Owner SUZHOU JONATHAN NEW MATERIALS TECH
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