Traditional Chinese medicine for preventing postpartum hemorrhage and preparation method of traditional Chinese medicine

Abstract

The invention provides traditional Chinese medicine for preventing postpartum hemorrhage and a preparation method of the traditional Chinese medicine. The traditional Chinese medicine comprises rhizoma angiopleris officinalis, physochlaina macrophylla, lethariella zahlbruckneria, hedysarum polybotrys, flemingia philippinensis, velutinous indigo root, Ficus harlandii Benth., auricularia polytricha, Ludwigia hyssopifolia, hair weed, Angelica niyida Wolff, myrtle, limonite, Elsholtzia cillata Hyland, wheatgrass, coelogyne fimbriata and Lepisorus pseudonudus. The traditional Chinese medicine has exact curative effect on preventing postpartum hemorrhage and is small in toxic and side effects.

Description

technical field

[0001] The invention relates to a medical preparation containing components derived from plants, animals or minerals, in particular to a traditional Chinese medicine for preventing postpartum hemorrhage and a preparation method thereof. Background technique

[0002] Postpartum hemorrhage is heavy bleeding that is difficult to stop after childbirth. This is a very serious, but uncommon complication. It is not life-threatening if treated promptly. Bleeding can occur if the uterus is too loose or if it fails to contract due to a long and exhausting labor, or if the birth wound is too large. An overdilated uterus may be due to multiple births, large fetuses, polyhydramnios, maternal weakness such as anemia, fright, or excessive fatigue. Malformation of the placenta also prevents the uterus from contracting symmetrically.

[0003] Globally, postpartum hemorrhage is still the most common cause of maternal death, and effective control of postpartum hemorrhage ca...

Examples

preparation example Construction

[0043] The present invention also provides the preparation method of above-mentioned Chinese medicine, when the dosage form of described Chinese medicine is capsule, its preparation method comprises the following steps:

[0044] The first step is to mix the various raw materials of the traditional Chinese medicine in proportion, add ethanol with an alcohol concentration of 85-95% relative to the mass of the mixture, heat and reflux for 1-3 hours, extract, and filter to obtain the first extract Adding the obtained dregs by filtration with ethanol with an alcohol concentration of 85-95% relative to the quality of the dregs 1-2 times, heating and refluxing for 1-3 hours, extracting, and filtering to obtain a second extract; The liquid and the second extract are combined, concentrated under reduced pressure to remove the ethanol solvent, and dried to obtain a dry paste;

[0045] In the second step, the dry paste obtained in the first step is placed in an ultrafine pulverizer for 1...

Embodiment 1

[0052] Embodiment 1: Capsules

[0053] Take Dingxinsan 200g, Huashan ginseng 60g, golden ribbon 280g, red qi 230g, Qianjinba 230g, snow ginseng 180g, water paulownia 150g, fungus 160g, grass dragon 190g, guoshanlong 280g, hair 270g, hemp mother 190g , Myrtle 160g, Yuyuliang 220g, Banbiansu 200g, Agropyron 120g, Fritillaria 280g and Changwawei 250g.

[0054] Its preparation method comprises the following steps:

[0055] The first step is to mix the raw materials of the traditional Chinese medicine in proportion, add ethanol with an alcohol concentration of 95% that is 4 times the mass of the mixture, heat and reflux for 3 hours, extract, and filter to obtain the first extract; filter the obtained dregs Then add ethanol with an alcohol concentration of 95% relative to the quality of the dregs, heat and reflux for 3 hours, extract, and filter to obtain the second extract; combine the first extract and the second extract, and concentrate under reduced pressure to remove Ethanol ...

Embodiment 2

[0058] Embodiment 2: glucose injection

[0059] Take Dingxinsan 260g, Huashan ginseng 80g, golden ribbon 260g, red qi 190g, Qianjinba 220g, snow ginseng 240g, water paulownia 180g, fungus 210g, grass dragon 160g, Guoshanlong 240g, hair 220g, hemp mother 170g , Myrtle 190g, Yuyuliang 180g, Banbiansu 170g, Agropyron 90g, Fritillaria 240g and Changwawei 170g.

[0060] Prepare as follows:

[0061] In the first step, the raw medicinal materials are mixed in proportion, put into an ultrafine pulverizer and pulverized into a mixed powder composed of micron-sized particles with a volume average particle size of 5 μm and nano-sized particles with a volume average particle size of less than 0.1 μm , the powder yield of the mixed powder is at least 95%;

[0062] In the second step, in the mixed powder obtained in the first step, add ethanol with an alcohol concentration of 85% relative to the quality of the mixed powder that is 3 times the mass of the mixed powder, stir and dissolve to...

technical field

[0001] The invention relates to a medical preparation containing components derived from plants, animals or minerals, in particular to a traditional Chinese medicine for preventing postpartum hemorrhage and a preparation method thereof. Background technique

[0002] Postpartum hemorrhage is heavy bleeding that is difficult to stop after childbirth. This is a very serious, but uncommon complication. It is not life-threatening if treated promptly. Bleeding can occur if the uterus is too loose or if it fails to contract due to a long and exhausting labor, or if the birth wound is too large. An overdilated uterus may be due to multiple births, large fetuses, polyhydramnios, maternal weakness such as anemia, fright, or excessive fatigue. Malformation of the placenta also prevents the uterus from contracting symmetrically.

[0003] Globally, postpartum hemorrhage is still the most common cause of maternal death, and effective control of postpartum hemorrhage ca...

Examples

preparation example Construction

[0043] The present invention also provides the preparation method of above-mentioned Chinese medicine, when the dosage form of described Chinese medicine is capsule, its preparation method comprises the following steps:

[0044] The first step is to mix the various raw materials of the traditional Chinese medicine in proportion, add ethanol with an alcohol concentration of 85-95% relative to the mass of the mixture, heat and reflux for 1-3 hours, extract, and filter to obtain the first extract Adding the obtained dregs by filtration with ethanol with an alcohol concentration of 85-95% relative to the quality of the dregs 1-2 times, heating and refluxing for 1-3 hours, extracting, and filtering to obtain a second extract; The liquid and the second extract are combined, concentrated under reduced pressure to remove the ethanol solvent, and dried to obtain a dry paste;

[0045] In the second step, the dry paste obtained in the first step is placed in an ultrafine pulverizer for 1...

Embodiment 1

[0052] Embodiment 1: Capsules

[0053] Take Dingxinsan 200g, Huashan ginseng 60g, golden ribbon 280g, red qi 230g, Qianjinba 230g, snow ginseng 180g, water paulownia 150g, fungus 160g, grass dragon 190g, guoshanlong 280g, hair 270g, hemp mother 190g , Myrtle 160g, Yuyuliang 220g, Banbiansu 200g, Agropyron 120g, Fritillaria 280g and Changwawei 250g.

[0054] Its preparation method comprises the following steps:

[0055] The first step is to mix the raw materials of the traditional Chinese medicine in proportion, add ethanol with an alcohol concentration of 95% that is 4 times the mass of the mixture, heat and reflux for 3 hours, extract, and filter to obtain the first extract; filter the obtained dregs Then add ethanol with an alcohol concentration of 95% relative to the quality of the dregs, heat and reflux for 3 hours, extract, and filter to obtain the second extract; combine the first extract and the second extract, and concentrate under reduced pressure to remove Ethanol ...

Embodiment 2

[0058] Embodiment 2: glucose injection

[0059] Take Dingxinsan 260g, Huashan ginseng 80g, golden ribbon 260g, red qi 190g, Qianjinba 220g, snow ginseng 240g, water paulownia 180g, fungus 210g, grass dragon 160g, Guoshanlong 240g, hair 220g, hemp mother 170g , Myrtle 190g, Yuyuliang 180g, Banbiansu 170g, Agropyron 90g, Fritillaria 240g and Changwawei 170g.

[0060] Prepare as follows:

[0061] In the first step, the raw medicinal materials are mixed in proportion, put into an ultrafine pulverizer and pulverized into a mixed powder composed of micron-sized particles with a volume average particle size of 5 μm and nano-sized particles with a volume average particle size of less than 0.1 μm , the powder yield of the mixed powder is at least 95%;

[0062] In the second step, in the mixed powder obtained in the first step, add ethanol with an alcohol concentration of 85% relative to the quality of the mixed powder that is 3 times the mass of the mixed powder, stir and dissolve to...

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