43 results about "Hedysarum polybotrys" patented technology

The invention belongs to the traditional Chinese medicine field and relates to the preparation of effective parts of astragalus mongholicus and hedysarum polybotrys and selection thereof for pulmonary fibrosis model intervention so as to obtain further study on the effective parts having the optimal curative effect. An interstitial pulmonary fibrosis model of rats is established through modeling; and compared with the normal rats, the rats having interstitial pulmonary fibrosis have obvious difference and pathologic change typical cases in various related detection indexes and pathologic changes. The various effective parts of astragalus mongholicus and hedysarum polybotrys are capable of suppressing various related indexes of the interstitial pulmonary fibrosis model of rats induced by bleomycin and preventing the development of interstitial pulmonary fibrosis, wherein low and medium dose groups of hedysarum polybotrys flavone have the optimal effect. The degree of the effect of the effective parts of astragalus mongholicus and hedysarum polybotrys on stopping the progress of interstitial pulmonary fibrosis is related to appropriate concentrations of equivalent dugs. Through comprehensive assessment, the hedysarum polybotrys flavone is better in influence on the lung function, HA, LN, HYP and the like of the rats having interstitial pulmonary fibrosis than other effective parts.

The invention provides a method for preparing a hedysarum polybotrys extract by adopting a coupling technology. The method comprises the following steps of: carrying out heating reflux extracting on hedysarum polybotrys; adding commercially available pectinase in a water extracting solution with the temperature of 15-60 DEG C; carrying out enzymolysis and sedimentation; removing insoluble impurities to obtain an enzymolysis extracting solution; carrying out ultra-filtering on the enzymolysis extracting solution; or, directly carrying out ultra-filtering on the water extracting solution; carrying out ultra-filtering on diluted trapped fluid for 2-4 times under the same condition, i.e. diluting the trapped fluid subjected to ultra-filtering each time and then carrying out ultra-filtering on the diluted trapped fluid subjected to ultra-filtering, ensuring that the volume of the trapped fluid subjected to ultra-filtering for the last time does not exceed 20 percent of the volume of the enzymolysis extracting solution, and merging all filtrated solutions to obtain a total filtrated solution; carrying out nanofiltering and concentrating on the total filtrated solution; concentrating trapped fluid subjected to nanofiltering under reduced pressure, and drying to obtain a hedysarum polybotrys full-ingredient extract; or concentrating the trapped fluid subjected to nanofiltering to be an extracting solution with corresponding concentration for preparing liquid preparation. According to the method, the process period for preparing the hedysarum polybotrys extract can be effectively shortened, the production cost is reduced, the extract quality is improved, and environmental protection is favored.

The invention relates to a purpose of radix hedysari or hedysarum polybotrys saccharide to treatment of ischemic vascular diseases. Particularly, on the basis of observing that the hedysarum polybotrys saccharide has the effect of promoting the primary generation blood vessel ring bud growth effect, the effect of the radix hedysari or hedysarum polybotrys saccharide for preventing and treating the ischemic vascular diseases is discovered. The invention further relates to a medicine composition containing the radix hedysari or hedysarum polybotrys saccharide for treating the ischemic vascular diseases.

The invention discloses medicine composition for treating central nervous system diseases. The medicine composition is prepared from, by weight, 5-60 parts of salidroside and 1-30 parts of hedysarum polybotrys saccharide. The invention further provides a preparation method of the medicine composition. The invention further provides a preparation method and a specific application of the medicine composition. Pharmacological experiments prove that the medicine composition can remarkably improve the learning and memory capacity of a D-galactose induced dementia mouse model by reducing oxidative products in brain tissue and improving activity of antioxidant enzymes in the brain and can remarkably improve the cognitive function of a vascular dementia rat. Besides, the medicine composition has an anti-hyperlipidemic effect to different extents after the medicines are matched.

The invention belongs to the traditional Chinese medicine field and relates to the preparation of effective parts of astragalus mongholicus and hedysarum polybotrys and selection thereof for pulmonary fibrosis model intervention so as to obtain further study on the effective parts having the optimal curative effect. An interstitial pulmonary fibrosis model of rats is established through modeling; and compared with the normal rats, the rats having interstitial pulmonary fibrosis have obvious difference and pathologic change typical cases in various related detection indexes and pathologic changes. The various effective parts of astragalus mongholicus and hedysarum polybotrys are capable of suppressing various related indexes of the interstitial pulmonary fibrosis model of rats induced by bleomycin and preventing the development of interstitial pulmonary fibrosis, wherein low and medium dose groups of hedysarum polybotrys flavone have the optimal effect. The degree of the effect of the effective parts of astragalus mongholicus and hedysarum polybotrys on stopping the progress of interstitial pulmonary fibrosis is related to appropriate concentrations of equivalent dugs. Through comprehensive assessment, the hedysarum polybotrys flavone is better in influence on the lung function, HA, LN, HYP and the like of the rats having interstitial pulmonary fibrosis than other effective parts.

The invention relates to a composite dipeptide ginseng-cistanche deserticola liquor for warming and tonifying essence and qi in the kidney, a composite dipeptide ginseng-cistanche deserticola granules prepared by reutilizing and processing wastes generated by processing health-care liquor, and a processing method thereof. Specifically, the processing method comprises the following steps: respectively separating an ethanol extracting solution of red ginseng, hedysarum polybotrys, fructus psoraleae and cistanche deserticola, an alcoholization solution of pomegranate fruits, lotus plumule and mulberry fruits and an enzymatic hydrolysate of oyster peptide and red date peptide by using a roll type ultrafiltration membrane with the molecular weight of 50,000; processing and drying the separated material liquid with the molecular weight of less than 50,000 to prepare the health-preserving health-care liquor which is low in drinking amount every time and easy to absorb; and carrying out freeze drying on the separated macromolecular material liquid with the molecular weight larger than 50,000 and red ginseng, hedysarum polybotrys, fructus psoraleae and cistanche deserticola material liquid extracted with water, then processing into the health-preserving health-care granules, or processing into tablets and pills. The wastes are reprocessed, fully utilized, and turned into wealth, the best use of materials is achieved, the wastes can be prevented, cost can be saved, and environmental pollution can be reduced.

The invention relates to an external ointment for treating bedsore and a preparation method thereof. The external ointment is composed of total 16 medicinal materials as follows: calcined gypsum, flat-stemmed tetrastigma leaf, hedysarum polybotrys, vitis flexuosa leaves, potentilla freyniana bornm, coriaceous knotweed rhizome, concha meretricis sea cyclinae, sedum lineare, puffball, water caltrap shell, bark of Chinese redbud, basil root, Chinese incarvilla herb, huperzia serrata, calamine and borneol. The external ointment provided by the invention has the effects of promoting blood circulation to remove blood stasis, promoting tissue regeneration and relieving pain, converging wound and moisturizing skin, and is capable of improving the blood circulation of the pressed tissue of a bedridden patient, moisturizing skin, and promoting growth of new granulation tissue; the external ointment is good in effects of converging sores and promoting tissue regeneration, and thus capable of promoting quick healing of the bedsore wounds. Besides, the external ointment provided by the invention is obvious in treatment effect, low in cost, quick in taking effect and accurate in curative effect; the healed skin is as smooth as before, and has pores regrown without scars.