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Composition and preparation method for treating swine mycoplasma and porcine pleuropneumonia

A technology for porcine pleuropneumonia and Mycoplasma suis is applied in the directions of drug combinations, medical raw materials derived from arthropods, medical preparations containing active ingredients, etc. Simple, good treatment effect, easy to generalize effect

Active Publication Date: 2018-10-02
DALIAN NATIONALITIES UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Chinese patent CN104208328A patent application provides a kind of traditional Chinese medicine composition for preventing and treating porcine infectious pleurisy, but the inventor finds in practice that the effect of the medicine preparation is not ideal, and there are problems such as slow treatment and low cure rate, and often disappear after stopping the medicine. Recurrence, therefore how to effectively treat porcine pleurisy has always been a big problem puzzling those skilled in the art
[0004] At present, the above two diseases are mainly treated by vaccines and antibiotics. Vaccines require chest inoculation, which is not easy to popularize. Once antibiotics or chemically synthesized drugs are used for a long time, pathogenic bacteria will continue to develop drug resistance, making the disease more and more difficult to control. and treatment, and the problem of drug residues has not been ignored
[0005] So far, the research on using traditional Chinese medicine to prevent and treat swine asthma is not deep enough, and there are no relevant reports on the pharmaceutical composition that can simultaneously play a certain therapeutic effect on swine pleurisy

Method used

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  • Composition and preparation method for treating swine mycoplasma and porcine pleuropneumonia
  • Composition and preparation method for treating swine mycoplasma and porcine pleuropneumonia
  • Composition and preparation method for treating swine mycoplasma and porcine pleuropneumonia

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] (1) Weigh 15g of herb, 18g of Fangfeng, 10g of licorice, 15g of almond, 30g of astragalus, 15g of aster, 15g of sunburnt flower, 10g of sunburned ephedra, 10g of cicada, 13g of forsythia, 25g of double flower, and crush them to 80-120 head;

[0032] (2) Add water 15 times the total mass of each traditional Chinese medicine to the pulverized aster, sunburned winter flower, sunburned ephedra, cicada, astragalus, and double flower, and cook at 90-100°C for 2 hours, and then use the total weight of each traditional Chinese medicine to boil for 2 hours. 5 times the mass of ethanol reflux extraction twice, the concentration of ethanol is 80vt%, the extraction temperature is 65 ° C, and the extract is filtered with filter paper for each extraction, and it is set aside;

[0033] (3) Add water 8 to 10 times the total mass of each traditional Chinese medicine to the crushed Atractylodes atractylodis, Fangfeng, licorice, almond and forsythia, boil for 2 hours at 90 to 100°C, and t...

Embodiment 2

[0036] (1) Weigh 15g of herb, 20g of Fangfeng, 10g of licorice; 10g of almond, 30g of astragalus, 15g of aster, 10g of sunburnt flower, 15g of sunburned ephedra, 10g of cicada, 10g of forsythia, 20g of double flower, and crush them to 80-120 head;

[0037] (2) Add water 15 times the total mass of each traditional Chinese medicine to the pulverized aster, sunburned winter flower, sunburned ephedra, cicada, astragalus, and double flower, and cook at 90-100°C for 3 hours, and then use the total weight of each traditional Chinese medicine to boil for 3 hours. 5 times the mass of ethanol reflux extraction twice, the concentration of ethanol is 80vt%, the extraction temperature is 60 ° C, and the extract is filtered with filter paper for each extraction, and it is set aside;

[0038] (3) Add water 10 times the total mass of each traditional Chinese medicine to the crushed Atractylodes atractylodis, Fangfeng, licorice, almond and forsythia respectively, cook at 90-100°C for 2 hours, ...

Embodiment 3

[0041] (1) Weigh 16 parts of Cangzhu, 18 parts of Fangfeng, 12 parts of Licorice; 13 parts of Almond, 33 parts of Astragalus, 16 parts of Aster, 12 parts of Sunburnt Flower, 13 parts of Sunburned Ephedra, 13 parts of Chan Yi, 12 parts of Forsythia, Double spend 28 copies. Crush to 80-120 mesh respectively;

[0042] (2) Add water 15 times the total mass of each traditional Chinese medicine to the pulverized aster, sunburned winter flower, sunburned ephedra, cicada, astragalus, and double flower, and cook at 90-100°C for 2 hours, and then use the total weight of each traditional Chinese medicine to boil for 2 hours. 5 times the mass of ethanol reflux extraction twice, the concentration of ethanol is 80vt%, the extraction temperature is 65 ° C, and the extract is filtered with filter paper for each extraction, and it is set aside;

[0043] (3) Add water 10 times the total mass of each traditional Chinese medicine to the crushed Atractylodes atractylodis, Fangfeng, licorice, almo...

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Abstract

The invention relates to the field of veterinary drugs, in particulrl to a composition for treating swine mycoplasmal pneumonia and porcine contagious pleuropneumonia and a preparation method thereof. The composition is prepared from, by weight, 15-20 parts of rhizoma atractylodis, 15-20 parts of radix saposhnikoviae, 10-13 parts of liquorice, 10-15 parts of apricot kernels, 30-35 parts of radix astragali, 15-20 parts of radix asteris, 10-15 parts of flos farfarae, 10-15 parts of herba ephedrae, 10-15 parts of periostracum cicada, 10-15 parts of fructus forsythiae and 20-30 parts of lonicera japonica. The composition has the effects of clearing heat, discharging fire, diminishing inflammation, resisting bacteria and the like, all the traditional Chinese medicines are proportioned reasonably to complement and coordinate mutually, the good treatment effect on the swine mycoplasmal pneumonia and the porcine contagious pleuropneumonia is achieved, the treatment course is short, the effects are rapid to achieve, and the cure rate is high; meanwhile, the preparation method of the composition is simple, safe, reliable, free of pollution and residues and easy to popularize.

Description

technical field [0001] The invention relates to the field of veterinary medicine, in particular to a composition for treating swine mycoplasma and porcine pleuropneumonia and a preparation method of the composition. Background technique [0002] Mycoplasma pneumonia of swine (Mycoplasmal pneumonia of swine) is a chronic, contact, respiratory infectious disease caused by Mycoplasma hyopneumoniae, also known as swine endemic pneumonia, commonly known as swine asthma. The infection rate and morbidity rate of this disease are all very high, and popularizes fast, and except causing pig's death, also can cause sick pig to carry bacteria for a long time and infect each other. Mycoplasma can be transmitted through the air medium, and its transmission route is difficult to be isolated and blocked. Therefore, mycoplasma pneumonia is recognized as one of the most difficult pig diseases to purify, and it has brought great harm to the global pig industry. [0003] Porcine pleurisy is an...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/736A61P11/00A61P31/04A61K35/64
Inventor 杜雄伟李叶邹民发王玉山梁军陈朝喜
Owner DALIAN NATIONALITIES UNIVERSITY
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