Micro-fluidic chip used for capturing and rotating micro-size particles and preparation method and application of micro-fluidic chip

A microfluidic chip, micro-scale technology, applied in chemical instruments and methods, laboratory containers, laboratory utensils, etc., can solve problems such as high requirements for electrical properties, inability to achieve effective rotation, etc., to achieve good universality. sexual effect

Inactive Publication Date: 2016-01-13
HARBIN INST OF TECH
View PDF8 Cites 20 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The present invention aims to solve the problem of the rotation control of existing micro-nano scale particles. The rotation strongly depends on the polarization relationship between the particle and the solution, so the requirements for the electrical properties of the particles are relatively high. , the problem of its effective rotation cannot be realized, and a microfluidic chip for capturing and rotating micro-scale particles and its preparation method and application are provided

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Micro-fluidic chip used for capturing and rotating micro-size particles and preparation method and application of micro-fluidic chip
  • Micro-fluidic chip used for capturing and rotating micro-size particles and preparation method and application of micro-fluidic chip
  • Micro-fluidic chip used for capturing and rotating micro-size particles and preparation method and application of micro-fluidic chip

Examples

Experimental program
Comparison scheme
Effect test

specific Embodiment approach 1

[0051] Specific implementation plan one: combine figure 1 Describe this embodiment in detail. This embodiment is a microfluidic chip for capturing and rotating microscale particles. The microfluidic chip for capturing and rotating microscale particles consists of a PDMS cover sheet 10 and an ITO glass substrate 3 ;

[0052] The central position of the ITO glass substrate 3 is provided with a square suspension electrode 1, an excitation electrode a2 is arranged behind the square suspension electrode 1, an excitation electrode b7 is arranged on the left side of the square suspension electrode 1, and an excitation electrode b7 is arranged in front of the square suspension electrode 1. Excitation electrode c8, the excitation electrode d4 is set on the right side of the square suspension electrode 1;

[0053] The said square suspension electrode 1, the excitation electrode a2, the excitation electrode b7, the excitation electrode c8 and the excitation electrode d4 are obtained by ...

specific Embodiment approach 2

[0060] Embodiment 2: The differences between this embodiment and Embodiment 1 are: the side length of the square suspension electrode 1 is 300 μm; the distance between the excitation electrode a2 and the excitation electrode c8 is 2 mm; The distance between the excitation electrode b7 and the excitation electrode d4 is 2mm. Others are the same as in the first embodiment.

specific Embodiment approach 3

[0061] Embodiment 3: The difference between this embodiment and Embodiment 1 or 2 is: the diameter of the circular inlet through hole 6 is 4 mm to 5 mm; the diameter of the circular outlet through hole 5 is 4mm-5mm; the diameter of the circular reaction chamber 9 is 5mm-10mm. Others are the same as in the first or second embodiment.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention discloses a micro-fluidic chip used for capturing and rotating micro-size particles and a preparation method and application of the micro-fluidic chip and relates to a micro-fluidic chip and a preparation method and application of the micro-fluidic chip. The problems that rotating and controlling of existing micro-nano-size particles depend on the polarization relation of the particles and a solution, and the requirement for electric attributes of the particles is high are solved. According to the chip, a square suspended electrode is arranged at the center of an ITO glass substrate, four excitation electrodes are arranged on the periphery of the square suspended electrode respectively, a particle runner is arranged on the surface of a PDMS cover sheet, a round reaction cavity is arranged in the center of the particle runner, a round inlet through hole is formed in one end of the particle runner, and a round outlet through hole is formed in the other end of the particle runner. The side, provided with the electrode, of the ITO glass substrate and the lower surface of the PDMS cover sheet are relatively sealed. The preparation method includes the steps that firstly, the electrode is machined; secondly, a PDMS channel is machined; thirdly, the chip is prepared. The application includes the first aspect of preparing the particles and the second aspect of rotating microrods.

Description

technical field [0001] The invention relates to a microfluidic chip, a preparation method and application thereof. Background technique [0002] Microfluidic system is a new technology that has emerged rapidly with the rapid development of micromachining technology in recent years, involving mechanics, mechanics, biology and chemistry. In order to achieve the goal of manipulating micro-nano-scale fluids and particle objects in fluids. Generally speaking, the basic tasks of microfluidic systems are mainly used to drive micro-nano-scale fluids and manipulate micro-nano-scale particles. [0003] The rotation manipulation of micro-nano-scale particles can be widely used in the description of particle size characteristics, the detection of surface properties, etc., and is of great significance for clarifying the electrical properties of single cells such as surface conductance and capacitance. The electric rotation operation of traditional micro-nanoparticles is to apply a volt...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Applications(China)
IPC IPC(8): B01L3/00
Inventor 任玉坤姜洪源吴玉潘陶冶郎琦贾延凯侯立凯
Owner HARBIN INST OF TECH
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap