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Applications of compound gymnadenia conopsea (l.) r. br pills in preparation of essential tremor treating drugs

A primary, hand ginseng technology, applied in the field of medicine, can solve problems such as reports or researches on compound hand ginseng pills that have not been found

Active Publication Date: 2016-02-10
SHANDONG JINHE DRUG RES DEV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] After patent and literature search, no report or research on the use of Compound Shoushen Pill or other preparations of its formula for the treatment of essential tremor was found

Method used

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  • Applications of compound gymnadenia conopsea (l.) r. br pills in preparation of essential tremor treating drugs

Examples

Experimental program
Comparison scheme
Effect test

experiment example

[0020] Experimental example, clinical research on the treatment of essential tremor (ET) with Fufang Shoushen Pill

[0021] 1. Case selection

[0022] Case selection was performed according to the "Guidelines for the Diagnosis and Treatment of Essential Tremor (2009)" issued by the Parkinson's Disease and Movement Disorders Group of the Neurology Branch of the Chinese Medical Association, and other types of tremor were excluded. A total of 100 patients were admitted and treated, including 53 males and 47 females, aged 29-71 years, with an average age of 51.1 years, and a disease course of 0.5-12 years, with an average disease course of 6.4 years.

[0023] 2. Efficacy Evaluation Criteria

[0024] 1. Curative effect evaluation index

[0025] Symptoms and signs: tremor amplitude and tremor level, etc.

[0026] 2. Efficacy Judgment Criteria

[0027] According to the tremor grading criteria proposed by the Essential Tremor Research Group of the National Institutes of Health in ...

Embodiment 1

[0047] Example 1, Application of Compound Shoushen Pills in the Preparation of Drugs for the Treatment of Essential Tremor

[0048] Its usage and dosage are 0.3 grams per pill, 3 pills each time, 3 times a day.

Embodiment 2

[0049] Example 2, Application of Compound Shoushen Pills in the Preparation of Drugs for the Treatment of Essential Tremor

[0050] Simultaneously combined application with Anshen Pill.

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Abstract

The present invention relates to applications of compound gymnadenia conopsea (l.) r. br pills in preparation of essential tremor treating drugs, and belongs to the field of medicine. According to the present invention, the technical prejudice in the application field in the prior art is overcome; and clinical research results show that symptoms of the essential tremor can be significantly improved and the essential tremor treating effect can be achieved by separately using the compound gymnadenia conopsea (l.) r. br pills or combining the compound gymnadenia conopsea (l.) r. br pills and other drugs, the effect of the single use of the compound gymnadenia conopsea (l.) r. br pills is equivalent to the effect of the conventional drug propranolol hydrochloride, and the effect of the combination of the compound gymnadenia conopsea (l.) r. br pills, the nerve calming pills and / or propranolol hydrochloride is superior to the effect of the conventional drug propranolol hydrochloride (P <0.05).

Description

technical field [0001] The invention relates to the application of compound hand ginseng pills in the preparation of medicines for treating essential tremors, which belongs to the field of medicine. Background technique [0002] Essential tremor (or essential tremor, referred to as ET) is a group of common nervous system diseases characterized by tremors in the hands, upper limbs and head that occur with movement, mainly affecting young adults and middle-aged and elderly people. Although essential tremor is closely related to Parkinson's disease and may even be an important risk factor for Parkinson's disease, essential tremor is clearly distinguished from Parkinson's disease, and the tremor in Parkinson's disease is called "rest" tremor , Essential tremor is "action" tremor, that is, essential tremor does not visibly tremble when it is quiet, but only manifests when it is in motion, or the tremor is particularly obvious when the hand moves to a certain posture, such as brus...

Claims

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Application Information

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IPC IPC(8): A61K36/898A61K9/20A61P25/14A61K35/56A61K31/138A61K31/427
Inventor 孙绪丁任松鹏赵延霞魏永义李晗
Owner SHANDONG JINHE DRUG RES DEV
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