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Granules containing krill oil and traditional Chinese medicine extract and capable of lowering blood lipid and preparation method of granules

An extract and blood lipid-lowering technology are applied in the field of blood-lowering granules and their preparation to achieve the effects of stable product quality and mature production process

Inactive Publication Date: 2016-03-02
XIAMEN GUILONG INVESTMENT MANAGEMENT
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, since elevated blood lipids itself has no symptoms, patients need to go to the hospital for tests to know, and the lesions (atherosclerotic diseases) it causes are also a long-term process, so they are easily overlooked

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0016] Example Preparation of blood lipid particles

[0017] Formula krill oil 0.5kg

[0018] Polygonum multiflorum 20kg

[0019] Alisma 15kg

[0020] Polygonatum 10kg

[0021] Salvia 10kg

[0022] Weigh according to the above formula, put the Polygonum multiflorum, Alisma orientalis, Polygonatum odoratum, and Salvia miltiorrhiza in an extraction tank, add water (12 times + 8 times) to decoct 2 times, each one hour, the extract is concentrated, dried, and an appropriate amount of dioxide Silicon and starch, crushed, granulated with ethanol, and dried. Dissolve the krill oil with 95% ethanol, spray it into the granules, mix well, let stand to absorb for 30 minutes, add an appropriate amount of magnesium stearate, mix well, and fill the granules into bags, 10g per bag.

[0023] Pharmacological test:

[0024] Experimental animals: ICR male mice, provided by the Drug Safety Evaluation Research Center of Nanjing University of Traditional Chinese Medicine;

[0025] Medicine: the granules of the...

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PUM

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Abstract

The invention discloses granules containing krill oil and traditional Chinese medicine extract and capable of lowering blood lipid. The granules are prepared from, by weight, 0.2-0.8 part of krill oil, 18-22 parts of prepared polygonum multiflorum, 12-18 parts of rhizoma alismatis, 8-12 parts of radix polygonati officinalis and 8-12 parts of salviae miltiorrhizae. A preparation method of the granules includes: weighing the prepared polygonum multiflorum, rhizoma alismatis, radix polygonati officinalis and salviae miltiorrhizae according to the weight, extracting, concentrating, drying, crushing and adding auxiliary materials to prepare particles, spraying a krill oil-ethanol solution into the particles according to the weight, well mixing, and filling into bags. The granules have the advantages that the application blank of a krill oil and traditional Chinese medicine compound composition capable of lowering the blood lipid is filled up, the advantages of traditional Chinese medicine decoctions are inherited, the granules capable of lowering the blood lipid is high in medicine loading capacity, mature in production process and stable in quality, and the preparation process is feasible in large-scale production.

Description

technical field [0001] The invention relates to the technical field of medicine and health care, in particular to a hypolipidemic granule containing krill oil and traditional Chinese medicine extract and a preparation method thereof. Background technique [0002] In recent years, the morbidity and mortality of cardiovascular and cerebrovascular diseases (such as coronary heart disease, myocardial infarction, ischemic stroke, etc.) based on atherosclerosis have been increasing year by year, and have become a threat to the health and life of our people. "Number One Killer". Studies have found that elevated blood lipids are the most important risk factor for atherosclerosis. According to statistics, the prevalence of hyperlipidemia in my country is as high as 18.6%. According to this estimate, there are 250 million patients with hyperlipidemia in my country. However, since elevated blood lipids itself has no symptoms, patients need to go to the hospital for tests to know, an...

Claims

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Application Information

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IPC IPC(8): A61K36/8969A61K9/16A61P3/06A61K35/612
Inventor 王殿广梁纪军
Owner XIAMEN GUILONG INVESTMENT MANAGEMENT
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