Lactobacillus acidophilus and application thereof

A technology of Lactobacillus acidophilus and live bacteria preparations, applied in the field of microorganisms, can solve the problems of not being able to achieve gastrointestinal stress, and achieve high resistance to gastrointestinal stress

Inactive Publication Date: 2016-03-23
NORTHEAST AGRICULTURAL UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Although the Lactobacillus acidophilus KLDSAD1 and AD2 obtained from the study have good gastric acid tolerance, they still cannot achieve high gastrointestinal stress ability under h...

Method used

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  • Lactobacillus acidophilus and application thereof
  • Lactobacillus acidophilus and application thereof
  • Lactobacillus acidophilus and application thereof

Examples

Experimental program
Comparison scheme
Effect test

experiment example 5

[0071] The above-screened Lactobacillus acidophilus is used to prepare a pharmaceutical preparation. Cultivate the above-mentioned Lactobacillus acidophilus MRS medium; take 50ml of the Lactobacillus acidophilus cultured for 14 hours, centrifuge to get the sludge, and then dissolve it in 1ml of sterile PBS to obtain the sludge; stir the sludge evenly, and then follow the routine A clinically acceptable dosage form is prepared by adding suitable auxiliary materials. Dosage forms include various dosage forms such as capsules, tablets, and powders.

[0072]

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Abstract

The invention relates to lactobacillus acidophilus with high gastrointestinal tract stress resistance, wherein the preservation number of the lactobacillus acidophilus is CGMCC No.10436. The screened lactobacillus acidophilus has high gastrointestinal tract stress resistance, and can be applied to fields of food industry, medicine and the like, and thus a theoretical basis is laid for the further research on the gastrointestinal tract stress resisting mechanism of the lactobacillus acidophilus.

Description

technical field [0001] The invention relates to a strain of Lactobacillus acidophilus with high resistance to gastrointestinal stress, belonging to the technical field of microorganisms. Background technique [0002] The ExpertCommittee defines probiotics as "live microorganisms that, when ingested in a certain amount, can have health benefits, and this benefit exceeds the general inherent nutrition", which shows that: probiotics must be alive and exist in a high amount at the same time, The usual daily dose is 10 9 cell mass. Most strains of probiotics are of the genera Lactobacillus and Bifidobacterium, and these lactic acid bacteria have been used since they have a long documented history of producing fermented dairy products. [0003] When probiotics enter the body, they need to tolerate the acidic environment of the gastrointestinal tract and the bile salt environment of the gastrointestinal tract. Therefore, how to withstand gastric acid, intestinal acid and bile is ...

Claims

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Application Information

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IPC IPC(8): C12N1/20A23C9/127A61K35/747A61P1/14C12R1/23
Inventor 霍贵成徐敏蒙月月
Owner NORTHEAST AGRICULTURAL UNIVERSITY
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