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Method for preparing medicine composition for treating xerophthalmia

一种组合物、干眼症的技术，应用在中医药领域，能够解决疗效不甚理想、易复发、起不到根治作用等问题，达到延长泪膜破裂时间、增加泪液分泌量、疗效显著的效果

Inactive Publication Date: 2016-05-04
QINGDAO HUAZHICAO PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, artificial tears can only relieve local dryness and astringency symptoms, and cannot achieve a radical effect. It is very easy to relapse after stopping the drug, so the curative effect is not ideal.

Method used

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  • Method for preparing medicine composition for treating xerophthalmia
  • Method for preparing medicine composition for treating xerophthalmia

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] Weigh 250g of ginkgo leaves, 250g of ghost needle grass, 380g of emblica, 250g of mulberry leaves, and 100g of golden cherry seeds and combine them. Add water to be 8 times the weight of the medicinal materials, decoct for 1.5 hours, combine the decoctions, concentrate under reduced pressure at 0.08MPa and 70°C until the relative density is 1.15 at 70°C, add 95% (v / v) ethanol to make the alcohol content reach 75% (v / v), stirred, stood overnight, filtered, and the filtrate was concentrated under reduced pressure at 0.08MPa and 65°C to contain 3.5g / mL of the original drug, and 0.25% preservative potassium sorbate was added. Bottled.

Embodiment 2

[0019] Weigh 285g of ginkgo leaves, 210g of ghost needle grass, 350g of emblica, 220g of mulberry leaves, and 130g of golden cherry seeds and combine them, add water to decoct twice, add water for the first time to 10 times the weight of the medicinal materials, decoct for 2 hours, and decoct for the second time Add water to be 8 times the weight of the medicinal materials, decoct for 1.5 hours, combine the decoctions, concentrate under reduced pressure at 0.08MPa and 70°C until the relative density is 1.15 at 70°C, add 95% (v / v) ethanol to make the alcohol content reach 85% (v / v), stirred, left standing overnight, filtered, and the filtrate was concentrated under reduced pressure at 0.08MPa and 65°C to contain 3.5g / mL of the crude drug, and 0.25% by weight of preservative potassium sorbate was added. 20mL / bottle.

Embodiment 3

[0021] Weigh 220g of ginkgo leaves, 250g of ghost needle grass, 460g of emblica, 300g of mulberry leaves, and 80g of golden cherry seeds and combine them, add water to decoct twice, add water for the first time to 10 times the weight of the medicinal materials, decoct for 2 hours, and decoct for the second time Add water to be 8 times the weight of the medicinal materials, decoct for 1.5 hours, combine the decoctions, concentrate under reduced pressure at 0.08MPa and 70°C until the relative density is 1.20 at 70°C, add 95% (v / v) ethanol to make the alcohol content reach 80% (v / v), stirred, stood overnight, filtered, and the filtrate was concentrated under reduced pressure at 0.08MPa and 65°C to contain 3.5g / mL of the crude drug, and 0.25% preservative potassium sorbate was added. Bottled.

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PUM

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Abstract

The invention discloses a method for preparing a medicine composition for treating xerophthalmia. According to the method, folium ginkgo, spanishneedles herb, fruits of emblic leafflower, folium mori and cherokee rose fruits serve as raw materials for preparing the medicine composition. The medicine composition prepared through the method has the functions of nourishing yin for moistening dryness and nourishing blood for improving eyesight, divine water is produced, the eyes are moistened and nourished, and the eyeballs are lubricated.

Description

[0001] This application is a divisional case of the invention patent application proposed by the applicant Cui Yinfang (the name of the invention is: a pharmaceutical composition for the treatment of dry eye and its application, the application number is: 2014104125453, and the application date is: August 21, 2014) Application. technical field [0002] The invention belongs to the technical field of traditional Chinese medicine, and in particular relates to a method for preparing a pharmaceutical composition for treating dry eye. Background technique [0003] Dry eye, also known as xerophthalmia, refers to the lack or abnormal distribution of tears in front of the cornea, which leads to a decrease in tears and dryness of the eyeball surface. This can lead to abrasion, inflammation and even ulceration of the corneal surface, ultimately affecting vision. [0004] Western medicine believes that xerophthalmia is mainly related to factors such as excessive eye use, immune inflam...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/738A61P27/02
CPCA61K9/0048A61K9/0095A61K36/16A61K36/28A61K36/47A61K36/605A61K36/738A61K47/26A61K2236/331A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 姜良柱
Owner QINGDAO HUAZHICAO PHARMA CO LTD
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