Newcastle disease virus, infectious bronchitis and fowl adenovirus triple inactivated vaccine

Abstract

The invention provides a newcastle disease virus, infectious bronchitis and fowl adenovirus triple inactivated vaccine. The fowl adenovirus is I group fowl adenovirus serotype 4 YBAV-4 strain with the preservation number of CCTCC No.V201541. The adopted new I group fowl adenovirus serotype 4 YBAV-4 strain is high in TCID50 titer, high in immunogenicity and capable of resisting the attack of local isolated viruses of the fowl adenovirus disease. The prepared vaccine is high in safety performance, and no local or whole-body adverse reaction caused by the vaccine appears; comparison, conducted through analysis on character data, safety performance testing data and efficacy testing data during storage life testing, between the vaccine and a single vaccine of similar products shows that the triple vaccine has no obvious difference and is stable and effective; the efficacy testing result proves that the triple vaccine and three single-vaccine antibodies are all at a high level, the antibody production speed is higher compared with similar products, and antibodies of a control group are negative.

Description

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AI Technical Summary

Benefits of technology

This patented technology allows for safe production of an improved version of influenza viruses called XAV-9 (Xanthomonads) which have higher titers but fewer harmful side-effects such as encephalitis or other symptoms associated therewith when administered alone. These improvements make this type of virus safer and more efficient at producing its own proteins without causing any damage during use on humans.

Problems solved by technology

This patents discusses different types of bacteria called avian influenza virus ("AIV"), commonly known colds when they attack humans during their winter months. These viruses may spread from one bird into another's nest if left alone without proper treatment. They pose significant threat because these attacks could result in deteriorative respiration syndrome within 10-14 days post-hatch period until slaughter at home. There is currently lack effective treatments against both pandemics like Avian Infant Disease Outbreak("INF") and infestibiosis, making them difficult to control effectively.

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