A kind of preparation method of jiubing extract

Abstract

The present invention discloses an ilex rotunda Thunb extract preparation method. The method steps are as follows: 1) pretreatment of a medicinal material, to be more specific, an ilex rotunda Thunb medicinal material is cleaned, selected, washed, baked at 60 DEG C for 3 to 5 hours, and pulverized to 50 to 100 mesh for standby use; 2) flash extraction, to be more specific, the pretreated medicinal material and an extraction solvent are mixed and put into a flash extraction tank, a speed governor is started to control the rotation speed in 4000-10000r / min, the extraction time is 1-20min, the number of extraction times is 1 to 5, and after the extraction is finished, a filtrate is collected after filtration; 3) membrane concentration, to be more specific, after crude filtration, fine filtration and microfiltration of an extract liquid, the extract liquid passes through a nanofiltration membrane with the cutoff molecular weight of 100 to 500 for concentration, and the operating pressure is 0.5-3MPa; and 4) spray drying, to be more specific, an ilex rotunda Thunb extract can be obtained by spray drying of a membrane concentrate liquid. The method is high in technical process efficiency, low in energy consumption, and suitable for industrial production.

Description

technical field

[0001] The invention relates to a method for extracting and concentrating jiubing, and belongs to the technical field of extraction and separation of medicinal active ingredients. Background technique

[0002] Jiubiying is the dry bark of Ilex holly, a synonym of Baimuxiang. It is a traditional Chinese herbal medicine in southern my country. It has the functions of purging fire and detoxification, cooling blood to stop bleeding, promoting qi and relieving pain, etc. It is often used to treat summer heat and fever. , sore throat, damp-heat diarrhea, abdominal pain, rheumatic arthralgia, etc. Preliminary studies have shown that the main active ingredients of Gyubing extract are triterpenoids and triterpenoid saponins such as syringin and pelicin, which have the effects of clearing away heat and detoxification, reducing swelling and relieving pain, and are effective against both aerobic and anaerobic bacteria. It has good antibacterial effect.

[0003] Traditio...

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