Pharmaceutical composition for treating duck virus hepatitis and preparation method thereof

A technology of duck viral hepatitis and composition, which is applied in the direction of antiviral agents, pharmaceutical formulas, medical preparations containing active ingredients, etc., can solve the problems of high price, difficult disease control, easy recurrence, etc., and enhance immunity and disease resistance, remarkable preventive and therapeutic effects, and low drug residues

Inactive Publication Date: 2016-08-03
李佃场
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

High-immunity yolk antibodies have the disadvantage of being difficult to preserve. Sometimes repeated injections of high-immunity yolk antibodies are difficult to control the disease. Moreover, most of the production of yolk antibodies does not use duck eggs produced by ducks without specific pathogenic microorganisms, resulting in Pathogenic microorganisms are transmitted to ducks through egg yolk antibodies. Even if duck eggs produced by ducks without specific pathogenic microorganisms are used, since egg yolk itself is a kind

Method used

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preparation example Construction

[0056] The dosage form of the pharmaceutical composition is powder injection, and its preparation method comprises the following steps:

[0057] In the first step, the raw medicinal materials are mixed in proportion, put into an ultrafine pulverizer and pulverized into a mixture composed of micron-sized particles with a volume average particle size of 0.1-10 μm and nano-sized particles with a volume-average particle size of less than 0.1 μm Powder, the powder yield of the mixed powder is at least 95%;

[0058] In the second step, add ethanol with an alcohol concentration of 85% to 95% relative to the mass of the mixed powder that is 3 to 5 times the mass of the mixed powder obtained in the first step, stir and dissolve to obtain an ethanol solution, and put the ethanol solution in Stand still for 24-36 hours under the condition of 5°C-10°C, use the percolation method to slowly percolate at a rate of 1-2ml per minute, collect the percolation liquid, concentrate and dry, and put...

Embodiment 1

[0066] Embodiment 1 pharmaceutical composition 1

[0067] The embodiment of the present invention provides a pharmaceutical composition for treating duck viral hepatitis, which is made of the following raw materials in parts by weight: 22 parts by weight of Folium Folium, 1 part by weight of Toosendan, 30 parts by weight of Red Head Grass, 24 parts by weight of root, 32 parts by weight of halogen alkali, 26 parts by weight of forsythia, 20 parts by weight of rock green orchid, 30 parts by weight of Chinese cabbage, 24 parts by weight of American ginseng, 34 parts by weight of licorice, 40 parts by weight of lotus seed heart, 15 parts by weight of purple pearl Parts by weight, 22 parts by weight of versicolor versicolor, 32 parts by weight of chrysanthemum, 20 parts by weight of dandelion, 32 parts by weight of fisheye grass, 24 parts by weight of trichosanthes, 31 parts by weight of apocynum leaves, 35 parts by weight of cassia seed, 16 parts by weight of spring and ghost Need...

Embodiment 2

[0072] Embodiment 2 pharmaceutical composition 2

[0073]The embodiment of the present invention provides a pharmaceutical composition for treating duck viral hepatitis, which is made of the following raw materials in parts by weight: 22 parts by weight of Folium Folium, 1 part by weight of Toosendan, 30 parts by weight of Red Head Grass, 24 parts by weight of root, 32 parts by weight of halogen alkali, 26 parts by weight of forsythia, 20 parts by weight of rock green orchid, 30 parts by weight of Chinese cabbage, 24 parts by weight of American ginseng, 34 parts by weight of licorice, 40 parts by weight of lotus seed heart, 15 parts by weight of purple pearl Parts by weight, 22 parts by weight of versicolor versicolor, 32 parts by weight of chrysanthemum, 20 parts by weight of dandelion, 32 parts by weight of fisheye grass, 24 parts by weight of trichosanthes, 31 parts by weight of apocynum leaves, 35 parts by weight of cassia seed, 16 parts by weight of spring japonica, ghost ...

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Abstract

The invention discloses a pharmaceutical composition for treating duck virus hepatitis and a preparation method thereof. The pharmaceutical composition is prepared from folium isatidis, fructus toosendan, herb of malay blumea, roots of rhodomyrtus tomentosa, brine alkali, fructus forsythia, herb of rupestrine dragonhead, diaphragma juglandis, Indian rorippa herb, radix panacis quinquefolii, licorice roots, plumula nelumbinis, amur barberry roots, bigleaf beautyberry roots, coriolus versicolor, pine leaves, all-grass of poisonous buttercrp herb, herbal swertiae mileensis, flos chrysanthemi, herbal taraxaci, herb of bentham dichrocephala, radix trichosanthis, folium apocyni veneti, semen cassiae, homlockleaved moonwort and herb of spanishneedles. The pharmaceutical composition has the advantages that antibacterial and anti-inflammation effects are achieved, the prevention and treatment effect on ducklings suffering from duck virus hepatitis is remarkable, yin and yang can be balanced, the cure rate is high, the treatment course is short, the quantity of medicine residues is small, and meanwhile the immunity and disease resistance of the ducklings can be enhanced.

Description

technical field [0001] The invention relates to the field of veterinary medicine, in particular to a pharmaceutical composition for treating duck viral hepatitis and a preparation method thereof. Background technique [0002] Duck viral hepatitis is mainly an acute infectious disease caused by duck hepatitis virus. It has a short course of disease, high incidence, rapid spread and high mortality. Duck hepatitis virus (DHV) has three serotypes: I, II, and III. Types I and III are enteroviruses of the picornaviridae family, and type II is an astrovirus. There is no cross-immunity between the serotypes. , Most of the pathogens popular in my country are type I duck hepatitis virus. The disease occurs throughout the year, but it often occurs in spring or winter. It mainly affects ducklings within 3 weeks of age through digestive tract and respiratory tract infections. The mortality rate of ducklings within one week of age is as high as 95%, the mortality rate of ducklings at the...

Claims

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Application Information

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IPC IPC(8): A61K36/85A61P31/14A61K33/14
CPCA61K36/315A61K33/14A61K36/07A61K36/11A61K36/15A61K36/24A61K36/258A61K36/28A61K36/287A61K36/288A61K36/29A61K36/31A61K36/428A61K36/482A61K36/484A61K36/51A61K36/52A61K36/53A61K36/58A61K36/61A61K36/62A61K36/634A61K36/71A61K36/85A61K2236/15A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61K2236/55A61K2300/00
Inventor 李佃场
Owner 李佃场
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