Pharmaceutical composition for improving osteoarticular diseases, disintegrating tablet and preparation method thereof

Abstract

The invention provides a pharmaceutical composition for improving osteoarticular diseases, a disintegrating tablet and a preparation method thereof. The pharmaceutical composition comprises main materials and auxiliary materials. The main materials are composed of, by weight, 90-120 parts of glucosamine and 0.001-0.05 part of vitamin K. The glucosamine can stimulate chondrocytes to synthesize protein polysaccharide and collagen fiber so as to generate cartilage matrix and repair articular cartilage. Vitamin K controls bone and calcium metabolism such that effective mineral deposition and retention of calcium intake on bones are guaranteed, bone quality and bone mineral density are enhanced and repairing function of articular cartilage is effectively raised. By using glucosamine and vitamin K as the main material and controlling ratio of the two components within the above range, the two active components have a synergistic interaction so as to raise mechanical strength of bone tissues of a patent, effectively inhibit decline in bone mineral density of middle-aged and old people, completely improve symptoms of osteoarthritis and mitigate arthralgia. Therefore, bone health problems such as bone aging of middle-aged and old people are alleviated.

Description

technical field [0001] The invention relates to the field of medicine and health care, in particular to a pharmaceutical composition for improving bone and joint diseases, a disintegrating tablet and a preparation method thereof. Background technique [0002] Osteoarthritis is the most common joint disease, which is defined by the American College of Rheumatology as a heterogeneity of joint symptoms and signs caused by damage to the integrity of articular cartilage, subchondral bone plate and joint edge bone lesions Disease, that is, a chronic joint disease of degeneration of articular cartilage and secondary bone hyperplasia. Its main symptoms are pain and loss of function caused by the degeneration of articular cartilage. When a person enters middle age, the joint tissue begins to age slowly, and degenerative lesions appear, especially the weight-bearing knee and spinal joints are most vulnerable to damage. Among people aged 50 to 60, more than half suffer from osteoarth...

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Problems solved by technology

[0004] The main purpose of the present invention is to provide a pharmaceutical composition for improving bone and joint diseases, a disintegrating tablet and its preparation method, so as to solve the problem that the drugs for treating bone and joint diseases in the prior art cannot satisfy the diversification of related drugs or health products in the market. question of needs

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