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Eye drop and preparation method and application thereof

A technology of eye drops and chrysanthemum, applied in the direction of medical formula, medical preparations containing active ingredients, medical raw materials derived from ferns/filamentous plants, etc., can solve problems such as ineffective treatment of cataracts, and avoid activation reactions The efficiency is too low, the operation steps are simple, and the effect of avoiding the loss of pearl active ingredients

Inactive Publication Date: 2016-08-24
HEERSEN JIANGSU PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] The first object of the present invention is to provide an eye drop, which can activate proteolytic enzymes in the lens, thereby decomposing and absorbing the turbid protease in the lens, restoring the transparency of the lens, and then treating cataracts, and can To solve the technical problem that cataracts cannot be effectively treated by externally applied drugs in the prior art, the eye drops of the present invention have the advantages of good curative effect, quick effect, no repetition and no side effects, etc.

Method used

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  • Eye drop and preparation method and application thereof
  • Eye drop and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0049] According to parts by weight, 100 parts of pearl powder, 5 parts of plum slices, 5 parts of cassia seeds, 4 parts of chrysanthemums, 4 parts of horsetail, 1 part of menthol, 2 parts of borax, 5 parts of sodium chloride, and 871 parts of water are weighed for each raw material.

[0050] Then, the pearl powder is added into the citric acid aqueous solution with a concentration of 2.5%, and the mixed solution is heated to 100° C. and kept warm. During the heating and heat preservation process, the mixed solution is continuously stirred to activate the pearl powder. After stirring and activating at a stirring speed of 60 r / min for 3 hours under heat preservation conditions, the mixed solution was left to cool at room temperature, and then the cooled solution was filtered to obtain activated pearl powder.

[0051] Next, mix chrysanthemum, horsetail and menthol, add water and boil for 5 minutes, then cool the resulting mixed solution at room temperature, then filter the cooled...

Embodiment 2

[0054] Each raw material is weighed according to parts by weight of 200 parts of pearl powder, 10 parts of plum slices, 10 parts of cassia seeds, 8 parts of chrysanthemums, 8 parts of horsetail, 5 parts of menthol, 5 parts of borax, 10 parts of sodium chloride and 750 parts of water.

[0055] Then, the pearl powder is added into the citric acid aqueous solution with a concentration of 2.5%, and the mixed solution is heated to 100° C. and kept warm. During the heating and heat preservation process, the mixed solution is continuously stirred to activate the pearl powder. After stirring and activating at a stirring speed of 60 r / min for 3 hours under heat preservation conditions, the mixed solution was left to cool at room temperature, and then the cooled solution was filtered to obtain activated pearl powder.

[0056] Next, mix chrysanthemum, horsetail and menthol, add water and boil for 5 minutes, then cool the resulting mixed solution at room temperature, then filter the cooled...

Embodiment 3

[0059] Each raw material is weighed according to parts by weight of 50 parts of pearl powder, 5 parts of plum slices, 5 parts of cassia seeds, 8 parts of chrysanthemum, 8 parts of horsetail, 5 parts of menthol, 5 parts of borax, 10 parts of sodium chloride and 904 parts of water.

[0060] Then, the pearl powder is added into the citric acid aqueous solution with a concentration of 2.5%, and the mixed solution is heated to 100° C. and kept warm. During the heating and heat preservation process, the mixed solution is continuously stirred to activate the pearl powder. After stirring and activating at a stirring speed of 60 r / min for 3 hours under heat preservation conditions, the mixed solution was left to cool at room temperature, and then the cooled solution was filtered to obtain activated pearl powder.

[0061] Next, mix chrysanthemum, horsetail and menthol, add water and boil for 5 minutes, then cool the resulting mixed solution at room temperature, then filter the cooled sol...

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Abstract

The invention provides an eye drop. The eye drop can be used for activating proteolytic enzymes in crystalline lenses and recovering the transparency of the crystalline lenses so as to treat cataract and has the advantages of good treatment effect, high effect taking speed, no recurrence, no side effect and the like. Simultaneously, the invention further provides a preparation method for the eye drop. The method comprises the steps of taking ingredients of the eye drop as raw materials, and carrying out steps, i.e., physical mixing and activating so as to prepare the eye drop. The method has the advantages that the preparation method is simple in operation, the prepared eye drop has a good treatment effect, and the like. Further, the invention also provides application of the eye drop provided by the invention. The eye drop provided by the invention can be used for effectively recovering the transparency of the crystalline lenses and treating the cataract; meanwhile, the eye drop provided by the invention also has a very good treatment effect on ocular hypertension and particularly the ocular hypertension induced by acute glaucoma.

Description

technical field [0001] The invention relates to the field of eye drops, in particular to an eye drop and its preparation method and application. Background technique [0002] Cataract is an eye disease with the highest morbidity and blindness rate in the world. The blindness caused by cataract in the elderly in my country accounts for more than 60% of the blindness of all elderly people. According to the calculation of experts based on epidemiological theoretical modeling, there are more than 60 million cataract patients in my country, ranking first in various eye diseases. [0003] There is no unified understanding of the pathogenic mechanism of cataract, but it is generally believed that cataract is closely related to lens protein degeneration. In the early stage of the disease, patients often experience eye fatigue, blurred vision, deformation, and photophobia, and then their vision gets worse and worse, and eventually they become blind. [0004] At present, surgery is ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/482A61K9/08A61P27/06A61P27/10A61P27/12A61K35/618A61K33/22A61K33/14A61K31/045
CPCA61K9/0048A61K9/08A61K31/045A61K33/14A61K33/22A61K35/618A61K36/11A61K36/287A61K36/482A61K2236/331A61K2300/00
Inventor 马思荣
Owner HEERSEN JIANGSU PHARMA CO LTD
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