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A composition for sensitive skin care of infants and its preparation method

A technology for infants and young children, the composition is applied to the composition and preparation of prickly heat and/or mosquito bites, and the field of treating eczema in infants and young children can solve the problems that infants and young children are not suitable for long-term use, easy to recur, dry skin, etc., and achieve maintenance Pharmacodynamic material basis and clinical efficacy, the effect of overcoming large side effects and definite curative effect

Active Publication Date: 2021-08-31
山东新稀宝股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For example, corticosteroids are prone to relapse after drug withdrawal, and are prone to side effects such as dry skin, atrophy, telangiectasia, and pigmentation. Infants and young children should not use them for a long time; there are also some disinfectant products that generally contain chlorhexidine, etc. Chemical disinfectants are irritating to the skin, especially the eyes; there are also some traditional Chinese medicine extract products, but the application effect is not ideal due to the single ingredient

Method used

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  • A composition for sensitive skin care of infants and its preparation method
  • A composition for sensitive skin care of infants and its preparation method
  • A composition for sensitive skin care of infants and its preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0039] Embodiment 1: the preparation of the gel for treating infantile eczema, prickly heat and / or mosquito bites

[0040] Recipe: 5 parts of purslane extract, 3 parts of Sophora flavescens extract, 2 parts of white fresh root bark extract, 1 part of Scutellaria baicalensis extract, 1 part of hyaluronic acid.

[0041] Excipients: Glycerin, Butylene Glycol, Trehalose, Carbomer, Arginine.

[0042] Preparation:

[0043] (1) Preparation of purslane extract: Pulverize the purslane medicinal material, adopt low-temperature extraction process (supercritical CO 2 extraction, the extraction pressure is 20MPa, the extraction time is 2h, and the entrainer is 95% ethanol), to obtain the purslane extract;

[0044] (2) Preparation of Sophora flavescens extract: crush Sophora flavescens, and use low-temperature extraction process (supercritical CO 2 extraction, the extraction pressure is 25MPa, the extraction time is 1.5h, and the entrainer is 95% ethanol), to obtain the Sophora flavescen...

Embodiment 2

[0049] Embodiment 2: the preparation of the spray for treating infantile eczema, prickly heat and / or mosquito bite

[0050] Recipe: 5 parts of purslane extract, 3 parts of Sophora flavescens extract, 2 parts of white fresh root bark extract, 1 part of Scutellaria baicalensis extract, 0.1 part of hyaluronic acid.

[0051] Excipients: Glycerin, Butylene Glycol.

[0052] Preparation:

[0053] Purslane extract, Sophora flavescens extract, white fresh root bark extract, and Scutellaria baicalensis extract are conventional commercially available products, obtained by purchase.

[0054] Add hyaluronic acid, glycerin, and butanediol into purified water, heat to 75-85°C, and stir until completely dissolved; when the temperature drops to 45°C, add purslane extract, Sophora flavescens extract, and white fresh root bark extract 1. Scutellaria baicalensis extract, stirred evenly; and then prepared into a spray by a conventional method.

Embodiment 3

[0055] Embodiment 3: the preparation of the lotion for the treatment of infant eczema, prickly heat and / or mosquito bites

[0056] Formula: 10 parts of purslane extract, 8 parts of Sophora flavescens extract, 6 parts of white fresh root bark extract, 2 parts of Scutellaria baicalensis extract, 0.1 part of hyaluronic acid.

[0057] Excipients: Glycerin, Butylene Glycol

[0058] Preparation method: the preparation of purslane extract, Sophora flavescens extract, white fresh root bark extract and Scutellaria baicalensis extract are the same as in Example 1;

[0059] Add hyaluronic acid to glycerin and butylene glycol for dispersion, heat to 75-85°C, stir until completely dissolved; when the temperature drops to 45°C, add Sophora flavescens extract, peony root extract and white fresh root bark extract, Stir evenly; then prepare lotion by conventional method.

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Abstract

The invention discloses a composition for nursing sensitive skin of infants, mainly aimed at infants and young children's eczema, prickly heat, mosquito bites and other diseases. 0.1-10 parts of root bark extract, 0.1-10 parts of root bark extract, 0.1-10 parts of Scutellaria baicalensis extract, and 0.01-1 part of hyaluronic acid. The composition of the present invention is developed and designed according to the pathogenesis of eczema and prickly heat in infants and young children. It has strong pertinence, high safety, and definite curative effect through clinical verification. . The hyaluronic acid component in the composition cooperates with other traditional Chinese medicine extract components, so that the composition can not only clear away heat and detoxify, dehumidify and relieve itching, antibacterial and anti-inflammatory effects, but also moisturize, promote tissue repair, and protect the skin barrier. role.

Description

technical field [0001] The invention relates to a composition for nursing sensitive skin of infants and a preparation method thereof, in particular to a composition for treating infant eczema, prickly heat and / or mosquito bites and a preparation method thereof. Background technique [0002] Infant eczema is called ringworm of milk, ringworm of fetus, and ringworm of milk in traditional Chinese medicine. It was first seen in "Theory of the Causes of Diseases": the clinical manifestation is that the baby's head and face are prone to occur, the shape is like corn, scattered or dense, hazel red, scratching white scales; or broken flow Body water, soaked into pieces is the characteristic. The former belongs to the predominance of wind and heat, while the latter emphasizes the predominance of damp and heat. Its pathogenesis is intolerance by nature, delicate skin, loss of spleen and stomach transportation and transformation, damp and hot fetal fire inside, and invasion by rheumat...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/75A61K47/36A61K8/97A61K8/73A61P17/00A61P17/02A61Q19/00A61Q17/02A61Q15/00A61K31/728
CPCA61K8/735A61K8/97A61K31/728A61K36/185A61K36/489A61K36/539A61K36/75A61Q15/00A61Q17/02A61Q19/00A61K2300/00
Inventor 张之梅林彦良袁晓菲
Owner 山东新稀宝股份有限公司
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