A contact excitation light source for a fluorescence imaging detection system

Abstract

The invention discloses a contact-type excitation light source used for a fluorescence imaging detecting system, belonging to an auxiliary device capable of enhancing the imaging effect of the fluorescence detection device. According to the design, the contact-type excitation light source is in direct contact with the skin or the surface of the body tissue, therefore, exciting light reflected by the skin and the surface of the other body tissue can be shielded by the device, while the fluorescence generated by the exciting light penetrating through the skin or the other body tissue which irradiates the IGG can penetrate through an observation channel in the center of the device and be received by the fluorescence detection device. With the adoption of the device, the useless exciting light reflected back to the fluorescence detection device by the skin or the surface of the body tissue is well blocked, therefore, the influences of the large amount of reflected exciting light on the picture are eliminated, the signal to noise ratio of the picture is improved, and the effect of the picture is enhanced. The contact-type excitation light source can be widely applied to the technical fields of sentinel node biopsy, heart bypass surgery, venous flap detection and the like.

Description

technical field [0001] The invention relates to the field of optical medical auxiliary equipment, in particular to a contact excitation light source of a fluorescence imaging detection system and an auxiliary device capable of enhancing the fluorescence imaging effect of the fluorescence detection equipment. For biopsy of sentinel lymph nodes and enhancement of fluorescence under other body tissues. Background technique [0002] Sentinel lymph nodes are primary the tumor Special lymph nodes in the draining regional lymph nodes, which are primary the tumor The first batch of lymph nodes that lymph node metastasis must pass through. The clinical application of sentinel lymph node biopsy to make axillary lymph nodes without metastases breast cancer Patients avoid axillary lymph node dissection, thereby avoiding corresponding surgical complications such as upper limb lymphedema, which greatly improves the quality of life of patients, so it has attracted people's attention....

AI Technical Summary

Problems solved by technology

[0003] There are currently three methods to detect sentinel lymph nodes: (1) blue dye method, this method is relatively traditional, using blue dyes such as methylene blue, the effect is not good, and doctors need a long learning curve

(2) The nuclide detection method, because it involves radioactive elements, has a certain radiation effect on the human body, and at the same time it will pollute the environment, and it is more troublesome to use. It has not been promoted in clinical practice, and the equipment system is more expensive.

[0005] The currently published invention patent CN1976639B of "lymph node detection device", the invention patent of "minimally invasive surgery positioning and guiding equipment" 102988112B, and the equipment disclosed in CN 104274156A "equipment and method for detecting NIR fluorescence at sentinel lymph nodes" are in use Both of them need to be used at a distance of 5-30cm from the human body. After the excitation light irradiates the skin or other body tissues, part of the excitation light penetrates the skin and irradiates ICG, and part of it is reflected by the surface of the skin or other body tissues. A large amount of reflected excitation light is combined with ICG fluorescence. Received by infrared fluorescence detection equipment, the signal-to-noise ratio between ICG fluorescence and excitation light is not high, which will interfere with the image quality. Even if a high-performance filter (7) is used to block the excitation light received by the fluorescence detection equipment, it still cannot achieve a good Effect

For example, in sentinel lymph node biopsy surgery, the lymph nodes of most patients are relatively deep, and it is difficult to observe the specific location of lymph nodes using traditional fluorescence detection equipment under non-invasive conditions

As a result, multiple observations and estimation of the location of lymph nodes are required, resulting in cumbersome surgery and increasing the possibility of miscalculation

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