Detection method of traditional Chinese medicine pills

Abstract

The invention discloses a detection method of traditional Chinese medicine pills. The detection method comprises the steps of character detection and thin-layer chromatography qualitative identification, wherein the thin-layer chromatography qualitative identification comprises the qualitative identification of semen cassia and coffee senna seed, the qualitative identification of radix bupleuri and Bupleurum longiradiarum and the qualitative identification of orange osmanthus in the traditional Chinese medicine pills. By virtue of the detection method, the blending of coffee senna seed and Bupleurum longiradiarum in the traditional Chinese medicine pills is effectively controlled, and meanwhile, the traditional Chinese medicine pills contain the components of semen cassia, radix bupleuri and angelica, so that the condition of medicinal materials few medicinal materials are added or even not added is effectively controlled, the quality of medicines is guaranteed, and the medication safety is guaranteed.

Description

technical field [0001] The invention relates to a method for identifying medicinal ingredients, in particular to a method for detecting traditional Chinese medicine pills. Background technique [0002] Xiongdan pill is a traditional Chinese medicine pill recorded in the second volume of traditional Chinese medicine preparations in the "Drug Standards of the Ministry of Health". Its standard number is WS3-B-0460-90. Mastiff, chrysanthemum, plantain seed (salt), cassia seed, bupleurum, windproof, scutellaria baicalensis, horsetail, coptis powder, menthol, rhubarb, borneol, bear bile, are capsules made of pure traditional Chinese medicine, which have the function of clearing away heat and dissipating heat. Wind, the effect of relieving pain and removing nebula. It is clinically used for the treatment of conjunctival congestion, swelling, pain, embarrassment and tears caused by wind-heat or liver meridian damp-heat. The drug standard was the earliest drug standard formulated b...

AI Technical Summary

Problems solved by technology

[0004] Bupleurum is used in the prescription, and its main effect is to reconcile Shaoyang, harmonize the stomach, strengthen the body and eliminate evil, but because Bupleurum is a commonly used medicine and used in large quantities, and the production of Bupleurum is limited, the counterfeit product Daye Bupleurum bupleurum has also been used intentionally or unintentionally. Bupleurum bupleurum contains bupleurum toxin and acetylbupleurum toxin, both of which are toxic substances. Poisoning phytotoxicity incidents, so it is necessary to control Daye Bupleurum

"Shandong Pharmaceutical Industry" published the article "Supplement to the Inspection Method of Bupleurum Radix in 2000 Edition of the Chinese Pharmacopoeia" in the fifth issue of Volume 22 in 2003. There are obvious deficiencies: 24 hours of storage, the detection time is too long, which is not conducive to the control of drug production process and drug quality supervision and inspection; because the content of Bupleurum toxin and acetyl Bupleurum toxin is relatively low, the sample is only 2 μl, and the sample volume is too small , which affects the accuracy of the test; because the content of Bupleurum toxin and acetylbupleurum toxin is relatively low, it is not good to observe under ultraviolet light without color development, and the more important thing is the prescription of Xiaochaihu granules. It contains many ingredients and complex ingredients, and other ingredients will cause confusion and interference. Therefore, it is urgent to find a better way to control Dayebupleurum