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Parasite control agent or parasiticide

A technology of parasites and repellents, applied in the direction of organic active ingredients, anti-infective drugs, active ingredients of amides, etc., can solve the problems of increasing internal parasites, etc.

Inactive Publication Date: 2016-12-14
NIPPON SODA CO LTD
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, the problem that drug-resistant internal parasites will increase if a single drug is continuously used is also pointed out

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0386] Next, the following test examples show that the compound of the present invention is useful as an active ingredient of a parasite control or repellant agent for treating parasitic diseases.

[0387] First, examples of the amide compound (I) are shown in Tables 1-4. Table 1 shows substituents in the compound represented by formula (a). Table 2 shows substituents in the compound represented by formula (b). Table 3 shows substituents in the compound represented by formula (c). Table 4 shows substituents in the compound represented by formula (d).

[0388] It should be noted that in the table, Me represents a methyl group, and Et represents an ethyl group, n Pr represents n-propyl, i Pr represents isopropyl, n Bu represents n-butyl, s Bu means sec-butyl, t Bu means tert-butyl, i Bu represents isobutyl.

[0389]

[0390] [Table 1]

[0391]

[0392] [Table 2]

[0393]

[0394] [table 3]

[0395]

[0396]

[0397] [Table 4]

[0398]

[0399] [tab...

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Abstract

A parasite control agent or parasiticide that has an exceptional effect for controlling or exterminating parasites, especially endoparasites, and that can be safely used contains as an active ingredient at least one selected from compounds represented by formula (I) or salts thereof. (In formula (I), Cy represents a heteroaryl group or the like; X represents a halogeno group or the like; n is any integer of 0-5; when n is 2 or higher, the X may be the same as or different from each other; R1 represents an optionally substituted C1-6 alkyl group or the like; A represents a nitrogen atom or the like; R2, R3, and R4 each independently represent a hydrogen atom, optionally substituted C1-6 alkyl group, or the like; and R5 represents an optionally substituted C6-10 aryl group, optionally substituted heteroaryl group, or the like.)

Description

technical field [0001] The present invention relates to a composition useful as medicine or animal medicine, and more specifically, to a parasite effective in treating parasitic diseases caused by internal parasites such as harmful nematodes, tapeworms, and flukes that parasitize humans, animals, and fish Preventive or repellant. [0002] this application claims priority based on Japanese Patent Application No. 2014-088059 for which it applied to Japan on April 22, 2014, and uses the content here. Background technique [0003] Internal parasites parasitize in the bodies of humans, animals, and fish as hosts, causing various parasitic diseases. Examples of these internal parasites include nematodes, tapeworms, trematodes and the like. In order to prevent their damage, agents are usually used to control or repel internal parasites. The above-mentioned chemical agents not only scatter in the body of the animal but also sometimes around the animal, requiring safety to the env...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/17A61K31/41A61K31/4196A61K31/426A61K31/44A61K31/4402A61K31/444A61K31/47A61K31/4709A61K31/505A61K31/506A61P33/00
CPCA61K31/41A61K31/4196A61K31/426A61K31/44A61K31/4402A61K31/444A61K31/47A61K31/4709A61K31/505A61K31/17A61K31/4965A61K31/415A61K31/53A61K31/506
Inventor 岩佐孝男
Owner NIPPON SODA CO LTD
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