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A Multifunctional Regenerative Blood Purification System

A kind of blood purification and multi-functional technology, applied in dialysis system, blood circulation treatment, drug equipment and other directions, can solve the problems of high price of liver support system, adsorption of particles into the human body, loss of self-albumin, etc., to achieve reuse, The effect of shortening the treatment time and balancing the electrolyte concentration

Active Publication Date: 2018-06-12
黄昱
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, unreasonable design may lead to loss of self-albumin, adsorption of particles into the human body, low utilization rate of adsorbent, contamination of self-albumin by foreign albumin, etc., which will not only lead to expensive liver support system, but also cause toxin removal efficiency Low and potential safety hazard

Method used

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  • A Multifunctional Regenerative Blood Purification System
  • A Multifunctional Regenerative Blood Purification System
  • A Multifunctional Regenerative Blood Purification System

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 2

[0081] Used to remove toxins from the blood while requiring regeneration of toxin-bound albumin, see figure 1 , figure 2 with Figure 4 ;

[0082] Depend on Figure 4 It can be seen that in step (6) when removing excess water and water-soluble medium and small molecular toxins in the blood through the blood purification module, the B2 post-dilution mode is adopted, and the blood that has been adsorbed or not adsorbed to remove albumin-bound toxins can also be processed The third arterial jug 63 directly flows into the second high-flux dialyzer 72 to remove excess water and water-soluble small and medium molecular toxins in the blood, and then flows into the venous jug 64 while the dialysate replenishment mechanism replenishes the dialysate.

[0083] Other steps (1), step (2), step (3), step (4), and step (5) are the same as those in embodiment 1.

Embodiment 3

[0085] Used to remove toxins from the blood while requiring regeneration of toxin-bound albumin, see figure 1 , figure 2 , image 3 with Figure 4 .

[0086] Depend on image 3 with Figure 4 It can be seen that in step (6) when removing excess water and water-soluble medium and small molecular toxins in the blood through the blood purification module, the B1 pre-dilution mode and the B2 post-dilution mode are adopted at the same time, and the adsorption or non-adsorption removal is combined with albumin Toxic blood passes through the third arterial jug 63 and replenishes the dialysate through the dialysate replenishment mechanism, then flows into the second high-flux dialyzer 72 to remove excess water and water-soluble small and medium molecular toxins in the blood, and then flows into the venous jug 64 At the same time, the dialysate is replenished by the dialysate replenishment mechanism.

[0087] Other steps (1), step (2), step (3), step (4), and step (5) are the sa...

Embodiment 4

[0089] For blood purification only, without regeneration of toxin-bound albumin, see figure 1 , figure 2 with image 3 , dialysis check valve 21, replacement check valve 22, purification check valve 23, first drug intake check valve 25, bypass check valve 27, third drug intake check valve 29, waste liquid check valve 210, input The one-way valve 211 and the output one-way valve 212 are opened, and the working principle is as follows:

[0090] see figure 2 , after step (1) in Example 1, when it is not necessary to recover the albumin bound to the toxin, step (2) then the toxin-containing solution flows into the toxin adsorption device 9 through the second arterial pot 62, and in the toxin adsorption device In 9, the toxin in the toxin solution directly flows through without being adsorbed in the working mode in which the bypass check valve 27 is connected in series.

[0091] Other steps (1), step (3), step (4), step (5), and step (6) are the same as in embodiment 1.

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Abstract

The invention relates to a multifunctional regenerative blood purification system. The multifunctional regenerative blood purification system comprises a blood purification mechanism, a dialysate supplementing mechanism and a toxin adsorption mechanism and specifically comprises two high-throughput dialyzers, ultrafiltration pumps, power pumps, arterial pots, a vein pot, dialysis bags, an albumin container, a carbon absorption pillar, a resin absorption pillar and a waste liquid tank. During work, water-insoluble toxins combined with albumin in blood are cleared away through multiple adsorption across a fiber membrane, water-soluble medium molecule and micromolecule toxins in the blood are cleared away through continuous blood purification, electrolyte balance is effectively realized by means of a continuous blood purification technology, and regeneration and repeated use of an adsorbent (such as activated carbon and resin) are realized by the aid of desorption of the adsorbent. By means of the system, a few absorbents are consumed, a variety of toxins are cleared, electrolyte balance is rapid, the edema removal effect is good, the treatment time is short, the system cost is low, the safety is good, and personal treatment can be realized.

Description

technical field [0001] The invention belongs to the technical field of medical devices, and relates to a new type of liver function support system for acute and chronic liver failure and other diseases, that is, a system that can realize the regeneration and reuse of various adsorbents and increase the removal of toxins in the blood purification system Species, maintaining electrolyte balance in the body, eliminating human edema, improving blood purification efficiency, good biocompatibility, and the design of a new multifunctional regenerative blood purification system that can effectively prevent medical albumin and adsorbents from entering the human body. Background technique [0002] Liver failure has become a critical disease that threatens the health of our people, and its main causes are immune injury, virus invasion, drug abuse and long-term alcoholism. Liver transplantation is currently the most effective way to treat liver failure, but its clinical application is l...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61M1/16A61M1/36
CPCA61M1/1621A61M1/1656A61M1/3621A61M1/3635A61M1/3679A61M2202/0413A61M2202/0021A61M2202/0028
Inventor 丁卫平周晓明高大勇刘驰黄昱
Owner 黄昱
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