Preparation method of directly orally-taken traditional Chinese medicinal decoction dendrobium powder

A technology of traditional Chinese medicine decoction pieces and Dendrobium candidum, which is applied in the direction of medical formula, medical preparations containing active ingredients, powder delivery, etc., can solve the problems of missing sterilization steps, high wall breaking rate, foreign bacteria, etc., to avoid the effective ingredients Evaporation, good solubility in water, and low moisture content

Active Publication Date: 2017-02-15
昆明斛之梦制药有限公司
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  • Abstract
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AI Technical Summary

Problems solved by technology

The ball milling method takes a long time and has low efficiency. The airflow milling method is a dry milling method, which is not suitable for Chinese herbal medicines with various volatile components; the vibration milling method has the characteristics of high wall breaking rate and low cost.
But no matter which method is used, in the process of making Herbal Dendrobium officinale, sterilization is always an important missing link
[0005] The invention patent with the application number 201410004825.0 discloses a preparation method of Dendrobium officinale containing chemical tablets, which uses mechanical crushing and ultrasonic wall breaking to process Dendrobium officinale, but the sterilization method for the decoction pieces of Dendrobium officinale is still missing
[0006] Dendrobium officinale contains a lot of nutrients, which can easily become a breeding ground for bacteria, and Dendrobium officinale powder without sterilization steps is more likely to bring foreign bacteria to the human body when it is taken orally, which is not worth the candle.
At the same time, because the sterilization effect of powdered Chinese herbal medicine will be simpler and more efficient, so in the industry, Dendrobium candidum is usually crushed first and then sterilized. However, because the powdered medicine is not easy to transfer, it is easy to sterilize A large amount of loss is caused in the step, which increases the production cost in a disguised form

Method used

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  • Preparation method of directly orally-taken traditional Chinese medicinal decoction dendrobium powder

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Embodiment 1

[0031] A kind of preparation method of the Chinese medicine decoction pieces Dendrobium candidum powder that can be directly taken orally of the present embodiment, comprises the steps:

[0032] (1) Sterilization: Put Dendrobium officinale in ozone water for ozone sterilization, the ozone concentration of the ozone water is 25mg / L, the water temperature is 5°C, and the ozone sterilization time is 0.5h;

[0033] (2) Pulverization: use high-pressure water jet equipment to pulverize Dendrobium officinale to obtain a slurry of Dendrobium candidum with a solid content of 20%. The nozzle aperture of the high-pressure water jet equipment is 2.5mm, and the jet water pressure is 10mPa;

[0034] (3) Filtration: vacuum filter the Dendrobium officinale slurry by using a filter screen to obtain a filter slurry, and the filter screen has a pore size of 100 μm;

[0035] (4) Concentration: Concentrating the filter slurry under reduced pressure in a vacuum to obtain a thick slurry with a water...

Embodiment 2

[0038] A kind of preparation method of the Chinese medicine decoction pieces Dendrobium candidum powder that can be directly taken orally of the present embodiment, comprises the steps:

[0039] (1) Sterilization: place Dendrobium candidum in a breathable environment, and use indirect natural light to dry Dendrobium candidum for 2-3 days. After drying, the water content of Dendrobium candidum is ≥ 70%, and then put Dendrobium candidum in ozone water for sterilization. Ozone sterilization, the ozone concentration of the ozone water is 35mg / L, the water temperature is 15°C, and the ozone sterilization time is 2.0h;

[0040](2) Pulverization: use high-pressure water jet equipment to pulverize Dendrobium officinale to obtain a slurry of Dendrobium candidum with a solid content of 25%. The nozzle aperture of the high-pressure water jet equipment is 3.5mm, and the jet water pressure is 20mPa;

[0041] (3) Filtration: vacuum filter the Dendrobium candidum slurry by using a filter scr...

Embodiment 3

[0045] A kind of preparation method of the Chinese medicine decoction pieces Dendrobium candidum powder that can be directly taken orally of the present embodiment, comprises the steps:

[0046] (1) Sterilization: place Dendrobium candidum in a breathable environment, and use non-direct natural light to dry Dendrobium candidum for 2.5 days. After drying, the water content of Dendrobium candidum is ≥ 70%, and then put Dendrobium candidum in ozone water for ozone sterilization Bacteria, the ozone concentration of the ozone water is 30mg / L, the water temperature is 10°C, and the ozone sterilization time is 1.3h;

[0047] (2) Pulverization: use high-pressure water jet equipment to pulverize Dendrobium officinale to obtain a slurry of Dendrobium candidum with a solid content of 30%. The nozzle aperture of the high-pressure water jet equipment is 3mm, and the jet water pressure is 15mPa;

[0048] (A) Ultra-high static pressure: transfer the Dendrobium officinale slurry to a high-pre...

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Abstract

The invention relates to the technical field of traditional Chinese medicinal material processing, in particular to a preparation method of directly orally-taken traditional Chinese medicinal decoction dendrobium powder. The preparation method comprises the following steps: (1) sterilizing: putting dendrobium into ozone water for performing ozone sterilization; (2) crushing: crushing the dendrobium by a wet crushing method to obtain a dendrobium slurry; (3) filtering: performing vacuum suction filtration on the dendrobium slurry by using a filter screen to obtain a filtrate slurry; (4) concentrating: performing vacuum reduced pressure concentration on the filtrate slurry to obtain a concentrated slurry; (5) drying: performing vacuum freeze drying on the concentrated slurry to obtain the dendrobium powder. A finished product prepared by the preparation method is extremely fine powder which is 100% broken, and has good water solubility; the sterilizing effect is good; active components are basically not destroyed; the finished product is high in active component polysaccharide content, low in moisture content, sterile and long in shelf life.

Description

technical field [0001] The invention relates to the technical field of processing traditional Chinese medicinal materials, in particular to a preparation method of dendrobium officinale powder which can be directly orally taken as a decoction piece of traditional Chinese medicine. Background technique [0002] The traditional decoction pieces of Dendrobium officinale are generally directly dry crushed by Fengdou dry product. First of all, the finished powder of this method is generally sterilized by radiation, and other methods are difficult to sterilize, and radiation sterilization will leave a small amount of radioactive substances that are harmful to human health. The active ingredients of the drug are not fully released, which reduces the absorption and utilization of the medicinal materials. Therefore, a kind of Chinese medicine broken wall decoction pieces gradually rises on the market. [0003] According to the definition of Guangdong's "Research Standards for the Q...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8984A61K9/19
CPCA61K9/0053A61K9/19A61K36/8984
Inventor 张春艳卢续贞欧汉啸
Owner 昆明斛之梦制药有限公司
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