Influenza vaccine nasal vaccination system

A flu vaccine, transnasal technology, applied in the direction of antibody medical ingredients, inorganic non-active ingredients, aerosol delivery, etc., to achieve strong immune induction, less side effects, and maintain antigenicity
CN106573045AActive Publication Date: 2017-04-19TOKO YAKUHIN IND CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
TOKO YAKUHIN IND CO LTD
Publication Date
2017-04-19

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Abstract

The present invention pertains to an influenza vaccine nasal vaccination system in which an influenza vaccine composition characterized by including a gel base that contains a carboxyvinyl polymer and an influenza virus deactivated full particle antigen, and including no adjuvants, is packed into a medical syringe for administration to the mucus membrane of the nasal cavity.
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Description

technical field

[0001] The present invention relates to a nasal vaccination system for use in conjunction with a medical syringe for administering an influenza vaccine composition to the nasal mucosa. Background technique

[0002] Influenza is an acute respiratory infection caused by influenza virus, especially in winter. Also, influenza sometimes causes widespread epidemics that are severe enough to kill people. For influenza, influenza vaccination is known to have a certain preventive effect and can be widely administered before the epidemic season.

[0003] The only influenza vaccine licensed in Japan is the inactivated protein component of the influenza virus antigen for subcutaneous inoculation, and its split vaccine is currently used as a seasonal influenza vaccine. This subcutaneously administered vaccine is highly effective in preventing severe influenza such as pneumonia, but has low antibody-inducing activity in the mucosa of the upper respiratory tract at the si...

Claims

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