Methods for compensating long term sensitivity drift of electrochemical gas sensors exposed to nitric oxide

Abstract

Described are systems and methods for compensating long term sensitivity drift of catalytic type electrochemical gas sensors used in systems for delivering therapeutic nitric oxide (NO) gas to a patient by compensating for drift that may be specific to the sensors atypical use in systems for delivering therapeutic nitric oxide gas to LAa patient. In at least some instances, the long term sensitivity drift of catalytic type electrochemical gas sensors can be addressed using calibration schedules, which can factor in the absolute change in set dose of NO being delivered to the patient that can drive one or more baseline calibrations. The calibration schedules can be used reduce the amount of times the sensor goes offline. Systems and methods described may factor in in actions occurring at the delivery system and / or aspects of the surrounding environment, prior to performing a baseline calibration, and may postpone the calibration and / or rejected using the sensor's output for the calibration.

Description

technical field [0001] The present invention generally relates to systems and methods for compensating for long-term sensitivity drift of electrochemical gas sensors exposed to nitric oxide, eg, in a controlled environment. Background technique [0002] There are many variants of electrochemical sensors which, although they may look similar, function very differently. For example, some electrochemical sensors may be used to detect the presence of a particular gas, while other electrochemical sensors detect the concentration of a particular gas. Furthermore, some electrochemical sensors work with liquids and not with gases. Focusing on electrochemical gas sensors, some of these gas sensors use galvanic reactions, while others use catalytic reactions. Also, some of these gas sensors require electrical current to work, while others do not and in some cases, actually generate electrical current. Still further, among similar types of electrochemical sensors with the same elect...

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Problems solved by technology

[0004] In general, the use of this type of catalyzed electrochemical gas sensor in a system for delivering therapeutic nitric oxide gas to a patient is considered atypical and may exist when used in a more conventional manner (e.g. typical Toxic gas sensor applications) Issues not seen when using these sensors

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