Construction method and application of three-dimensional dose contribution distribution model with occlusion material

A distribution model, three-dimensional dose technology, applied in radiation therapy, X-ray/γ-ray/particle irradiation therapy, treatment, etc., can solve the problems of brachytherapy system error, inaccurate radiotherapy brachytherapy plan, etc., to improve the accuracy Effect

Inactive Publication Date: 2017-08-15
THE AFFILIATED HOSPITAL OF SOUTHWEST MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0006] However, in the traditional brachytherapy system, the three-dimensional dose distribution model constructed is aimed at the unshielded radiation source. Since the radiation source is shielded by the shielding material, the radiation will be absorbed by the shielding material and scattered, etc., and then use the original Some 3D dose distribution models will have large errors in the brachytherapy system, resulting in inaccurate brachytherapy planning. Therefore, it is necessary to construct a new 3D dose based on the new source applicator with shielding materials. distribution model

Method used

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  • Construction method and application of three-dimensional dose contribution distribution model with occlusion material
  • Construction method and application of three-dimensional dose contribution distribution model with occlusion material
  • Construction method and application of three-dimensional dose contribution distribution model with occlusion material

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Embodiment 1

[0052] This embodiment discloses a method for calculating the radiation dose contribution at the target point i when there is an occluding material between the radiation source j and the target point i, specifically including the following steps:

[0053] (1) Obtain calculation parameters, including the following:

[0054] Let radioactive source j be the origin of the coordinates, that is, the coordinates of radioactive source j are j(0, 0, 0), then the coordinates of target point i relative to radioactive source j are i(r i , θ i , );

[0055] Radiation time t is used as an independent variable of radiation dose contribution;

[0056] Shading material thickness L i , obtained according to the actual situation of the occlusion material;

[0057] The average attenuation coefficient of the occluding material for the radioactive source Based on the nature of the shielding material and the radioactive source;

[0058] The scattering ratio n of rays is obtained according t...

Embodiment 2

[0063] This implementation discloses a method for constructing a three-dimensional dose contribution distribution model with occlusion materials, including the following steps:

[0064] (A) Let the j coordinate of the radioactive source be (r j , θ j , ), then the coordinates of target point i relative to radioactive source j are (r ij , θ ij , );

[0065] (B) Suppose there are m target points i in the three-dimensional space where the radioactive source j is located, then the coordinates of the mth target point i are (r ijm , θ ijm , );

[0066] (C) According to the calculation method of the radiation dose contribution provided in claim 1, the radiation dose contribution of the radiation source j at the mth target point i is obtained:

[0067]

[0068] Where: S k is the air kerma intensity; ∧ is the dose rate constant; G(r, θ) is the geometric factor G (r, θ); g(r im , θ im ) is the radial dose function; F(r im , θ im ) is a directional function; all of th...

Embodiment 3

[0072] This embodiment discloses the application of a three-dimensional dose contribution distribution model with occlusion materials as an auxiliary tumor brachytherapy plan formulation, as follows:

[0073] The single-tube afterloading source applicator was used as the main treatment device of the cervical cancer afterloading radiotherapy plan, and lead was selected as the shielding material of the single-tube afterloading source applicator, and Ir192 was used as the radioactive source, and Matlab software was used to simulate the single-tube afterloading source applicator. Install the three-dimensional dose distribution model of the source applicator.

[0074] Through the ordinary post-loading radiotherapy plan, 12 dwell points are obtained, which are:

[0075] x=-8:0.25:8; y=x; z=x;

[0076] [x,y,z]=meshgrid(x);

[0077] x lr1 =0,y lr1 = 0, z lr1 = 0.5;

[0078] x lr2 =0,y lr2 = 0, z lr2 = 1;

[0079] x lr3 =0,y lr3 = 0, z lr3 = 1.5;

[0080] x lr4 =0,y lr4...

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Abstract

The invention discloses a radiation dose calculating method with an occlusion material. A three-dimensional dose distribution model is established according to the method, and the three-dimensional dose distribution model is used for assisting the establishment of a tumor close range radiotherapy program. The invention provides the radiation dose calculating method which can accurately acquire the radiation dose at any point behind the occlusion material. The radiation dose calculating method with the occlusion material is used to construct the three-dimensional dose contribution distribution model with the occlusion material. The three-dimensional dose contribution distribution model can accurately represent the radiation range and radiation intensity of a radioactive source at the rear of the occlusion material, and can be applied widely. The protection and construction of the three-dimensional dose contribution distribution model with the occlusion material are applied to radiotherapy, which improves the establishment accuracy of the close range program and brings hope to patients treated with a single-tube close range source applicator.

Description

technical field [0001] The invention relates to the technical field of intracavity radiotherapy, in particular to a method for constructing a three-dimensional dose contribution distribution model with shielding materials and its application. Background technique [0002] Radioactivity means that elements spontaneously emit radiation from unstable nuclei (such as alpha rays, beta rays, gamma rays, etc.) and decay to form stable elements and stop emitting (decay products). This phenomenon is called radioactivity. There are many fields where radiation can be applied, such as nuclear power generation in industry, eliminating static electricity, understanding fertilizer absorption and loss of insects in agriculture, archaeology can be used to identify the age of ancient objects, and the most important application is in medicine. Tumor treatment. [0003] Tumor radiotherapy is a local treatment method that uses radiation to treat tumors. It is mainly used for malignant tumors. ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61N5/10
CPCA61N5/1002A61N5/1031A61N5/1075
Inventor 庞皓文
Owner THE AFFILIATED HOSPITAL OF SOUTHWEST MEDICAL UNIV
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