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A kind of antibacterial lotion and its preparation method and application

A technology of lotion and concentrate, applied in antibacterial drugs, pharmaceutical formulations, antifungal agents, etc., can solve the problems of adverse reactions of chemical drugs (allergic reactions, long development cycle of antibiotics, fast mutation speed of bacteria, etc.) Wound healing, low toxicity, less irritation effect

Active Publication Date: 2021-02-02
武汉赛景生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Prevention of wound infection and promotion of wound healing are basic surgical issues. Disinfectants and antibiotics have been widely used clinically. There are many problems such as high price, long development cycle of antibiotics, rapid mutation of bacteria, etc.

Method used

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  • A kind of antibacterial lotion and its preparation method and application
  • A kind of antibacterial lotion and its preparation method and application
  • A kind of antibacterial lotion and its preparation method and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] The present embodiment provides a kind of antibacterial lotion, by weight, this antibacterial lotion mainly comprises following raw material components:

[0038]

[0039] Wherein, the Chinese medicine extract is an extract concentrate with a relative density of 1.04-1.06, and the raw material of the medicine includes the following components:

[0040]

[0041] The antibacterial lotion of the present embodiment is prepared by the following method:

[0042] Use water to decoct and extract the raw materials of traditional Chinese medicine three times (the water here is not included in the raw material water of the antibacterial lotion, the same below), 1280L water for the first time, 800L water for the second time, 800L water for the third time, and 800L water for the first time Extract for 40 minutes, decoct and extract for 30 minutes each for the second and third times, let cool, filter, combine the filtrates and concentrate to obtain a concentrated solution (50°C)...

Embodiment 2

[0053] The present embodiment provides a kind of antibacterial lotion, by weight, this antibacterial lotion mainly comprises following raw material components:

[0054]

[0055] Wherein, the Chinese medicine extract is an extract concentrate with a relative density of 1.04-1.06, and the raw material of the medicine includes the following components:

[0056]

[0057] The antibacterial lotion of the present embodiment is prepared by the following method:

[0058] Use water to decoct and extract the raw materials of traditional Chinese medicine for three times, 1600L water for the first time, 1000L water for the second time, 1000L water for the third time, 40 minutes for the first extraction, 30 minutes for the second and third decoction extractions, Let cool, filter, combine the filtrates and concentrate to obtain a concentrated solution (50°C) with a relative density of 1.08-1.10;

[0059] Add 95% ethanol to the concentrated solution until the alcohol content of the con...

Embodiment 3

[0069] The present embodiment detects the effect of the antibacterial lotion obtained in Example 1 on promoting wound healing, and the specific methods are as follows:

[0070] 18 rabbits were shaved on the back. On the 1 / 3 of the head side of the back and 1.5 cm beside the spine, a rectangular wound with a size of 3 cm × 4 cm was designed symmetrically on the left and right, and the long axis was parallel to the spine. After local anesthesia with 1% procaine, the skin and superficial fascia were completely removed according to the design, until the superficial surface of the deep fascia, and the wound was wrapped with sterile dry gauze. They were randomly divided into 3 groups, namely normal control group (normal saline), positive control group (iodine) and antibacterial lotion group. Dosing twice a day, continuous administration until 95% of the wound surface is healed as the healing standard, and the healing days of each wound surface are recorded. The results are shown in...

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Abstract

The invention provides an antibacterial lotion. The antibacterial lotion mainly comprises the following raw materials and components in parts by weight: 200-300 parts of a traditional Chinese medicine extracting solution, 0.2-1.5 parts of chlorhexidine, 15-25 parts of tween-80, 30-40 parts of glycerinum, 0.5-3 parts of clove oil, and 150-200 parts of water, wherein the traditional Chinese medicine extracting solution is the extract condensate at relative density of 1.04-1.06; the traditional Chinese medicine comprises the following components in parts by weight: 40-50 parts of cortex phellodendri, 40-50 parts of rheum officinale, 30-50 parts of phemeranthus, and 40-50 parts of radix scutellariae. The invention also provides a preparation method and the application of the abovementioned antibacterial lotion. The antibacterial lotion is capable of treating gynecological disease, burn, scald, trauma and postoperative traumatic reaction; the traditional Chinese medicine extract is used as the main component of the antibacterial lotion, so that the irritation to skin, mucosa and wound is low; the anaphylaxis is hardly caused; the antibacterial lotion is low in toxicity and even free from toxicity.

Description

technical field [0001] The invention relates to an antibacterial lotion and its preparation method and application, belonging to the technical field of medicines. Background technique [0002] Gynecological diseases are the general term for common diseases of the female reproductive system. Gynecological diseases are common and frequently-occurring diseases of women. However, many people lack proper understanding of gynecological diseases, lack of physical health care, and various bad living habits. The gradual decline in physical health has caused some women to suffer from diseases that cannot be cured for a long time, which has brought great inconvenience to normal life. Most of the common gynecological diseases are caused by the growth of bacteria, and lotions are commonly used for sterilization. There are many types of lotions in the market, mainly western medicine lotions, which eliminate microorganisms on the surface or mucous membranes. , in order to achieve the purp...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/155A61K36/756A61K9/08A61K47/26A61P15/00A61P15/02A61P31/02A61P31/04A61P31/10A61P31/22
CPCA61K9/0014A61K9/08A61K31/155A61K36/185A61K36/539A61K36/61A61K36/708A61K36/756A61K47/26A61K2236/331A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 宫念樵
Owner 武汉赛景生物科技有限公司