Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Placenta extract biogel preparation for treating premature ovarian failure and preparation method thereof

A biological gel and premature ovarian failure technology, applied in the biological field, can solve problems affecting product efficacy and waste, avoid safety and immune rejection problems, treat premature ovarian failure, and improve the effect of premature ovarian failure

Active Publication Date: 2020-08-18
GUANGZHOU ZHUNYOU BIOLOGICAL TECH CO LTD
View PDF3 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] At present, the use of placenta is mostly in the form of oral administration, soup supplementation, capsules, freeze-dried powder, etc. However, due to the unique fishy smell of placenta, it will make users feel sick to a certain extent, and the way of taking it orally will affect it to a certain extent. The efficacy of the product is reduced, resulting in waste

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Placenta extract biogel preparation for treating premature ovarian failure and preparation method thereof
  • Placenta extract biogel preparation for treating premature ovarian failure and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0039] Embodiment 1 A kind of placenta extract biogel preparation

[0040] The placenta extract biogel preparation of this embodiment is prepared from placenta extract, carbomer, ethylparaben, propylene glycol, water-soluble azone, and triethanolamide. 98% of the volume of the gel preparation.

[0041] The preparation method of the placenta extract biogel preparation of the present embodiment comprises the following steps:

[0042] (1), select 100 mL of fresh healthy placenta tissue after selection;

[0043](2) Fully wash the placental tissue and cut it into small pieces, remove the blood vessels and mucosal tissue, put it in 100mL50mmoL / L acetic acid-sodium acetate buffer solution (pH4.0) for homogenization; place the homogenate at 4°C Incubate in a water bath for 2.5 hours, stirring occasionally during the period; after returning to room temperature, refrigerate and centrifuge (4°C, 6600r / min, 30min) to obtain a precipitate and about 150mL of supernatant;

[0044] (3), at...

Embodiment 2

[0051] Embodiment 2 A kind of placenta extract biogel preparation

[0052] The placenta extract biogel preparation of this example is prepared from placenta extract, gelatin, ethylparaben, propylene glycol, and water-soluble azone, and the volume of the placenta extract accounts for 95.2% of the volume of the biogel preparation.

[0053] The preparation method of the placenta extract biogel preparation of the present embodiment comprises the following steps:

[0054] Steps (1)-(7) are the same as in Example 1.

[0055] (8), take 12.6g of gelatin and add 100ml of placenta extract, and make water-hydrocolloid after fully swelling; take 0.15g of ethylparaben, dissolve it in 7.5ml of propylene glycol, and then add the solution to gelatin water -Add 0.75g of water-soluble azone to the hydrocolloid, then add the placenta extract to make up to 157.5ml, keep stirring until it forms a beige gel, and then divide it into gel tubes or capsules to obtain the desired preparation .

[005...

Embodiment 3

[0057] Embodiment 3 A kind of placenta extract biogel preparation

[0058] The placenta extract biogel preparation of this embodiment is prepared from placenta extract, sodium carboxymethylcellulose, ethylparaben, propylene glycol, water-soluble azone and aluminum chloride, and the volume of placenta extract accounts for 96.2% by volume of the biogel formulation.

[0059] The preparation method of the placenta extract biogel preparation of the present embodiment comprises the following steps:

[0060] Steps (1)-(7) are the same as in Example 1.

[0061] (8), get sodium carboxymethyl cellulose 3.12g, add 100ml placenta extract, make water-hydrocolloid after fully swelling; Get the ethylparaben of 0.45g, be dissolved in 6ml propylene glycol, then Add the solution to the sodium carboxymethylcellulose water-hydrocolloid, stir well, add 2.25g of water-soluble azone, then add the placenta extract to 156ml, add aluminum chloride drop by drop, and keep stirring until it turns beige ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
particle sizeaaaaaaaaaa
particle sizeaaaaaaaaaa
particle sizeaaaaaaaaaa
Login to View More

Abstract

A placental extract biological gel preparation for treating premature ovarian failure, and a method of preparing same. The placental extract biological gel preparation is obtained from a gel base and placental extract, said extract serving as the active ingredient. The preparation may be used to treat premature ovarian failure.

Description

technical field [0001] The invention belongs to the field of biotechnology, and more specifically, the invention relates to a placenta extract biogel preparation for treating premature ovarian failure and a preparation method thereof. Background technique [0002] Premature ovarian failure (POF) refers to a disease caused by various etiologies in which women under the age of 40 experience amenorrhea, decreased estrogen secretion, and increased gonadotropin levels due to ovarian failure. [0003] The incidence of POF is increasing year by year, and the proportion of POF in female infertility patients is also increasing year by year. The two major threats of POF to women's reproductive health are the decrease of estrogen level and the loss of fertility. The decrease of estrogen level increases the risk of osteoporosis and coronary heart disease in women. Women who are in the childbearing period have early amenorrhea and loss of fertility, which will lead to a series of psycho...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61K35/50A61K9/06A61P15/08
CPCA61K9/06A61K35/50A61K47/42
Inventor 吴道贫李文禄赖小华陶然
Owner GUANGZHOU ZHUNYOU BIOLOGICAL TECH CO LTD
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com