Gene sequencing instrument

Abstract

The invention discloses a gene sequencing instrument. The gene sequencing instrument comprises a machine base, a sequencing platform and a reagent supply device, wherein the sequencing platform is provided with a gene sequencing chip; the reagent supply device is used for supplying a gene sequencing reagent to the gene sequencing chip and comprises a rotary disc and a rotary driving component, the rotary driving component is used for driving the rotary disc to rotate, and a plurality of mounting stations for mounting testing reagent cylinders are distributed on the rotary disc along the circumferential direction; the testing reagent cylinders comprise cylinder bodies and piston rods, the cylinders are used for storing the gene sequencing reagent, and the piston rods are arranged in sliding and telescopic manners relative to the cylinder bodies; and the reagent supply device further comprises a liquid outlet base, the base is fixedly arranged on the machine base and is provided with a liquid outlet, and outlets of the testing reagent cylinders are driven by the rotation o the rotary disc so as to be alternately butted with the liquid outlet so as to be located at a liquid supply station. According to the gene sequencing instrument, the gene sequencing reagent can be rapidly and precisely loaded, the loading efficiency and the gene sequencing efficiency are greatly improved, and the whole gene sequencing cycle can be substantially shortened.

Description

technical field [0001] The invention relates to a gene sequencer. Background technique [0002] Gene sequencing is a new type of genetic testing technology, which can analyze and determine the full sequence of genes from blood or saliva, predict the possibility of suffering from various diseases, and the behavioral characteristics and behavior of individuals are reasonable. Gene sequencing technology can lock individual disease genes, prevent and treat them in advance. Since the development of gene sequencing technology, the corresponding gene sequencer has also undergone earth-shaking changes, and its throughput, sequencing accuracy, sequencing cycle, read length, etc. are constantly improving, and its application is becoming more and more extensive. Components also mainly rely on gene sequencing chips to complete. [0003] In recent years, most of the research on gene sequencing has been carried out around the development of gene chips, and has also achieved outstanding ...

AI Technical Summary

Problems solved by technology

[0003] In recent years, most of the research on gene sequencing has been carried out around the development of gene chips, and has also achieved outstanding achievements and development. However, the gene sequencers currently used in clinical or research basically still use large-scale factory-level chips. Or a desktop-level sequencer, which requires professional technicians to manually load samples and other operations, and the technical requirements are very high

The sample volume cannot be precisely controlled each time the sample is loaded, and the sample loading efficiency is extremely low. If it is necessary to sequence the complete gene chain of a certain biological sample, it usually takes at least one day to complete, and the sequencing cycle is long

Images