Device for sound distinguishing of small animal and synchronous electrophysiological-signal recording

A technology of electrophysiological signals and recording devices, which is applied in animal houses, diagnostic recording/measurement, closed-circuit television systems, etc., can solve the problems of lack of sound discrimination ability, achieve accurate and efficient methods, less damage, and realize free activities Effect

Pending Publication Date: 2018-03-16
XUZHOU MEDICAL UNIV
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  • Application Information

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Problems solved by technology

However, there is currently no accurate, rapid, highly automated method that can simultaneously monitor the electrophysiological signals in the animal brain to detect the sound discrimination ability of animals.

Method used

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  • Device for sound distinguishing of small animal and synchronous electrophysiological-signal recording
  • Device for sound distinguishing of small animal and synchronous electrophysiological-signal recording
  • Device for sound distinguishing of small animal and synchronous electrophysiological-signal recording

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Embodiment Construction

[0025] The present invention will be further described below in conjunction with the accompanying drawings and specific embodiments.

[0026] Such as figure 1 , The present invention provides a sound discrimination and synchronous electrophysiological signal recording device for small animals, including an activity room for placing small animals, a sound stimulation device, an electrophysiological recording device, a water supply device and a microcomputer. The sound stimulation device gives sounds of different parameters (including frequency, intensity and time characteristics, etc.), and generates corresponding event signals, and transmits the event signals to the microcomputer; the electrophysiological recording device is Record the electrophysiological signals of small animals (single-cell discharge and local field potential signals in specific brain regions), and transmit the signals to a microcomputer; the water supply device is a training task for studying the discrimin...

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Abstract

Provided is a device for sound distinguishing of a small animal and synchronous electrophysiological-signal recording. The device comprises an activity chamber used for placement and activities of thesmall animal, a sound stimulation device, a water supply device, an electrophysiology recording device and a micro-control computer; the sound stimulation device is used for giving sound with different parameters to the trained small animal and training the small animal to distinguish sound stimulation with different intensity or different time phases; the electrophysiology recording device is used for recording electrophysiological signals of the small animal and sending the signals to the micro-control computer; the water supply device is a given award during the task of studying sound stimulation distinguishing of the small animal; the micro-control computer receives event signals, conducts data collection and analyzing treatment on the event signals and then transmits a result to a corresponding display device for display. By means of the device, the electrophysiological signals and movement track signals of the small animal in the process of sound distinguishing can be accuratelyrecorded, and then electrophysiological signals during different hearing disorders can be studied and recorded to learn about the states of auditory functions so that whether or not a disease relative to hearing happens can be judged.

Description

technical field [0001] The invention relates to a sound recognition and synchronous electrophysiological signal recording device for small animals. Background technique [0002] Hearing is an important sense in humans and animals and plays a key role in intra- and inter-species communication. At the same time, hearing is closely related to many brain diseases such as schizophrenia. The study of hearing in animals (such as rats and mice) in the laboratory not only helps to develop new treatments for hearing impairment, but also screens for drugs that may treat or improve hearing impairment-related brain diseases. However, there are currently only a few methods in the laboratory that can evaluate the auditory function of animals, and in the existing methods, either the test accuracy is not enough and the repeatability is poor, or it takes a long time to train before the sound discrimination can be performed. test. In addition, if the electrophysiological signals (including ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B5/0484A61B5/0478A61B5/12A01K1/03A01K29/00H04N7/18
CPCA01K1/031A01K29/00A01K29/005A61B5/123A61B5/6868A61B2503/40A61B2503/42A61B5/291A61B5/38H04N7/18
Inventor 李安安毛兴峰操田田
Owner XUZHOU MEDICAL UNIV
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