Bifidobacteria as probiotic foundation species of gut microbiota

A technology of bifidobacterium and mucosal lactobacillus, applied in the direction of bacteria, microorganisms, microorganisms, etc.

Pending Publication Date: 2018-03-27
PERFECT CHINA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0012] In other words, currently existing probiotics have many l

Method used

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  • Bifidobacteria as probiotic foundation species of gut microbiota
  • Bifidobacteria as probiotic foundation species of gut microbiota
  • Bifidobacteria as probiotic foundation species of gut microbiota

Examples

Experimental program
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Effect test

Embodiment 1

[0116] Example 1 Dietary relief of genetic and simple obesity

[0117] 1. Genetic and simple obesity alleviated by dietary intervention, and the biological clinical parameters of patients with simple or genetic obesity improved

[0118] The WTP diet (14) was used in this inpatient intervention study on morbidly obese children suffering from PWS or SO. The two groups (SO, n=21, average age 10.52 years (3-16 years); PWS, n=17, average age 9.26 years (5-16 years)) had no significant difference in age (data not shown). Both groups received hospital intervention for 30 days. Due to the parents' request, the PWS group continued to intervene for another 60 days. A volunteer (GD02) stayed in the hospital for 285 days. During the dietary intervention, compared with their pre-intervention diet, the total caloric intake of the two groups of children was reduced by about 30%. Protein intake is maintained at 13-14% of the total calories consumed. The carbohydrate intake of the PWS group in...

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Abstract

This invention relates to novel probiotic Bifidobacteria strains, particularly, a B. pseudocatenulatum strain, and its use as probiotic, and food products, feed products, dietary supplements and pharmaceutical formulations containing them. The bacteria are suitable for the treatment of obesity, diabetes (particularly Type 2 diabetes), and related conditions.

Description

Technical field [0001] The present invention relates to novel Bifidobacterium strains and their uses, to foods, feed products, dietary supplements and pharmaceutical preparations containing them, and to methods of preparing and using these compositions. Background technique [0002] Probiotics, generally understood to mean "live microorganisms that exert health benefits to the host when administered in sufficient amounts", have been widely used in the prevention and treatment of many diseases, and their effectiveness is powerful in certain clinical situations evidence of. For example, WO 2007 / 043933 describes the use of probiotics in the manufacture of food, feed products, and dietary supplements to control weight gain, prevent obesity, increase satiety, prolong satiety, reduce food intake, and reduce fat deposition , Improve energy metabolism, enhance insulin sensitivity, treat obesity and treat insulin resistance. [0003] WO 2009 / 024429 describes the use of a basic composition...

Claims

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Application Information

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IPC IPC(8): C12N1/20A61P3/04
CPCC12N1/20A61K2035/115A61K35/747A61K35/745A61P43/00A61P3/10C12R2001/01C12N1/205
Inventor 赵立平张晨虹吴欢吴国军
Owner PERFECT CHINA
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