A normalized correction factor acquisition and determination method and medical imaging method

A technology of correction factor and acquisition method, applied in the field of image processing, can solve problems such as poor consistency, response line conforming to efficiency fluctuation, inability to judge noise, etc., to achieve stability and accuracy improvement, statistical accuracy improvement, and elimination of statistical errors. Effect

Active Publication Date: 2021-02-26
RAYSOLUTION DIGITAL MEDICAL IMAGING CO LTD
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Problems solved by technology

This effect will be very obvious for low counts, when there are only a few tens or even a few samples on each LOR, we can't even tell whether these events are noise
Therefore, when using the existing normalization correction method to correct the scanned PET data, there are the following two problems: 1. The response line conforms to the efficiency fluctuation, and the consistency is poor after normalization correction according to the existing method; 2. At present, the amount of sampled data is insufficient, and it is difficult to form an accurate normalized correction factor

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  • A normalized correction factor acquisition and determination method and medical imaging method
  • A normalized correction factor acquisition and determination method and medical imaging method
  • A normalized correction factor acquisition and determination method and medical imaging method

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[0045] The invention discloses a method for obtaining a normalized correction factor. In one embodiment, obtaining the normalized correction factor includes the following steps:

[0046] S1: Acquisition of actual data at a specified time for a phantom with an initial uniform activity, the volume of which covers the target imaging field of view.

[0047] As a preferred solution, in step S1, a PET detection system is used to collect data on a cylindrical phantom with uniform activity, and the imaging field of view is the three-dimensional space (field of view (FOV for short), that is, the prosthesis cannot be smaller than the FOV used, the activity range is 0.01mCi-50mCi, and the scanning time is 1min-200min. The cylindrical phantom is a cylindrical shell, and the inner cavity can be injected with a PET tracer solution to be used as a radiation source for imaging; the scanning time refers to the time from the start of the PET scan to the end of the scan; the collected data stor...

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Abstract

The invention discloses a method for obtaining a normalized correction factor, which comprises the following steps: S1 collects actual data for a specified time on a prosthesis with an initial uniform activity, and the volume of the prosthesis covers the target imaging field of view; S2 is based on the collected actual data. Data, get the actual event count SR of the i-th single channel i ; S3 based on the same activity and sampling time, collect theoretical data for the same size of the prosthesis; S4 based on the collected theoretical data, obtain the corresponding theoretical event count ST of the i-th single channel i ; S5 determines the normalization factor NS of the i-th single channel i =ST i / SR i . The normalized correction factor determined by this method is statistically based on the count rate of a single channel, which has low data requirements and can better reflect the detector characteristics of the system.

Description

technical field [0001] The invention relates to the technical field of image processing, in particular to a method for acquiring a normalized correction factor and a medical imaging method. Background technique [0002] PET is the abbreviation of Positron Emission Tomography in English. The clinical imaging process is as follows: label the radionuclides (such as F-18, etc.) in the subject's body. Allow the subject to perform a PET scan within the effective field of view of the PET. The positrons emitted by the radionuclide move about 1 mm in the body and combine with the negative electrons in the tissue to produce annihilation radiation, producing two gamma photons with equal energy (511KeV) and opposite directions. The detection device of the PET system can detect the gamma photon pair, and then analyze the existence of positrons, and reconstruct the PET image reflecting the metabolism of various tissues of the organism, and obtain the concentration distribution of the t...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61B6/03
CPCA61B6/037A61B6/582
Inventor 李炳轩
Owner RAYSOLUTION DIGITAL MEDICAL IMAGING CO LTD
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