Feed additive for livestock and poultry, capable of resisting diseases and promoting growth, and preparation method

A feed additive and growth-promoting technology, applied in animal feed, animal husbandry, additional food elements, etc., can solve the problems of immiscibility, difficult absorption and utilization, strong volatility, etc., and achieve good gastrointestinal mucosal affinity, The implementation method is simple and the effect of good controlled release performance

Inactive Publication Date: 2018-05-29
ZHEJIANG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This processing technology has obvious disadvantages: since cinnamaldehyde and carvacrol are insoluble in water, they cannot be completely homogeneously miscible with chyme in the intestinal tract after they are added to feed and eaten by animals, and are not easy to absorb and utilize
Although cinnamaldehyde and carvacrol have many effects on intestinal health, because they are easily absorbed into the circulatory system in the front part of the digestive tract, it is difficult to reach the intestinal tract to play a role, which greatly limits their efficacy
In addition, they are highly volatile and easily oxidized. If unprotected cinnamaldehyde and carvacrol are used, the stability of their active ingredients cannot be guaranteed

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment l

[0031] 1) Add montmorillonite, together with sodium chloride equivalent to 15% of the weight of montmorillonite, add water and stir evenly to make a suspension slurry with a concentration of 10%, sodiumize it at room temperature for 15 hours, wash 5 times with water, and remake it with water Ore pulp with a concentration of 20%;

[0032] 2) slowly adding cetylpyridinium chloride equivalent to 15% by weight of montmorillonite into the slurry in step 1) under stirring, and continuously stirring and reacting at room temperature for 8 hours;

[0033] 3) Carvacrol equivalent to 10% of the weight of montmorillonite is slowly added to the slurry of step 2) under stirring, and the reaction is continuously stirred at room temperature for 5 hours, and then cinnamaldehyde equivalent to 10% of the weight of montmorillonite is added, Stir for 3 hours;

[0034] 4) The reaction solution in step 3) is filtered and dehydrated, and the obtained filter cake is dried and pulverized to obtain a f...

Embodiment 2

[0041] 1) Add montmorillonite, together with sodium chloride equivalent to 5% of the weight of montmorillonite, add water and stir evenly to make a suspension slurry with a concentration of 20%, sodiumize it at room temperature for 10 hours, wash it with water 3 times, and remake it with water Ore pulp with a concentration of 45%;

[0042] 2) Slowly add cetylpyridinium chloride equivalent to 10% by weight of montmorillonite into the slurry in step 1) under stirring, and continuously stir and react at room temperature for 4 hours;

[0043] 3) Carvacrol equivalent to 2% of the weight of montmorillonite was slowly added to the slurry of step 2) under stirring, continuously stirred and reacted at room temperature for 3 hours, and then cinnamaldehyde equivalent to 2% of the weight of montmorillonite was added, Stir for 1.5 hours;

[0044] 4) The reaction solution in step 3) is centrifuged and dehydrated, and the obtained filter cake is dried and pulverized to obtain a feed additiv...

Embodiment 3

[0047] 1) Add montmorillonite, together with sodium chloride equivalent to 10% of the weight of montmorillonite, add water and stir evenly to make a suspension slurry with a concentration of 12%, sodiumize it at room temperature for 12 hours, wash it with water 3 times, and remake it with water Ore pulp with a concentration of 30%;

[0048] 2) Slowly add cetylpyridinium chloride equivalent to 11% by weight of montmorillonite into the slurry in step 1) under stirring, and continuously stir and react at room temperature for 6 hours;

[0049] 3) Carvacrol equivalent to 7% of the weight of montmorillonite is slowly added to the slurry of step 2) under stirring, and the reaction is continuously stirred at room temperature for 4 hours, and then cinnamaldehyde equivalent to 7% of the weight of montmorillonite is added, Stir for 2 hours;

[0050] 4) The reaction solution in step 3) is filtered and dehydrated, and the obtained filter cake is dried and pulverized to obtain a feed addit...

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PUM

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Abstract

The invention discloses a preparation method of a feed additive for livestock and poultry, capable of resisting diseases and promoting growth. Montmorillonite modified with cetylpyridinium chloride isused for loading carvacrol and cinnamaldehyde, is used as a release-slow carrier, has the characteristics of being high in specific surface area, high in suction force/desorption force, high in stability, low in cost, and the like, and can protect digestive tract mucosa. The montmorilloniteis is modified with the cetylpyridinium chloride, so that the layer spacing/ specific surface area and the hydrophobic character of the montmorillonite are improved, and the adsorption rate of the montmorillonite for the carvacrol and the cinnamaldehyde is increased. The montmorillonite is loaded with the carvacrol and the cinnamaldehyde, so that release control on entire intestines is facilitated, and the effects of resisting bacteria, resisting inflammation and resisting oxidation can be effectively exerted. The feed additive has the synergistic effect and the synergism effect on antibacterial activity, and can reduce the toxicity of the carvacrol and the cinnamaldehyde. The adsorption quantity oninner toxins by the carvacrol and the cinnamaldehyde is 0. The adsorption quantity on bacterial endotoxin by the feed additive for livestock and poultry, capable of resisting diseases and promoting growth, is 91EU/mg.

Description

technical field [0001] The invention relates to a feed additive for disease resistance and growth promotion of livestock and poultry and a preparation method thereof. Background technique [0002] Feed antibiotics are widely used in livestock and poultry feed, which can effectively prevent livestock and poultry diseases, improve production performance, and reduce breeding costs. However, the long-term addition of antibiotics has caused a series of serious problems such as the emergence of drug resistance of pathogenic bacteria, the decline of animal immune function, the imbalance of flora in the body, residues in meat, eggs and milk, and environmental pollution. People are increasingly aware of the adverse consequences of long-term use of antibiotics. From the perspective of development, banning and restricting the use of antibiotic feed additives has become the consensus of the world and is the trend of the times. The European Union first banned the application of antibio...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23K20/105A23K20/195
CPCA23K20/105A23K20/195Y02A40/70
Inventor 胡彩虹王春春曹舒婷章倩晖吴焕焦乐飞
Owner ZHEJIANG UNIV
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